Is there a role for anticoagulation with dabigatran in S. aureus bacteremia? Protocol for the adjunctive treatment domain of the Staphylococcus aureus Network Adaptive Platform (SNAP) randomised controlled trial.

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Title: Is there a role for anticoagulation with dabigatran in S. aureus bacteremia? Protocol for the adjunctive treatment domain of the Staphylococcus aureus Network Adaptive Platform (SNAP) randomised controlled trial.
Authors: McDonald EG; Department of Medicine, McGill University Health Centre, Montreal, Québec, Canada emily.mcdonald@mcgill.ca., Cheng MP; McGill University, Montreal, Québec, Canada., Davis JS; The University of Newcastle School of Medicine and Public Health, Callaghan, New South Wales, Australia., Goodman AL; Centre for Clinical Infection and Diagnostics Research, Guy's and Saint Thomas' NHS Foundation Trust, London, UK.; King's College London Faculty of Life Sciences and Medicine, London, UK., Lawler PR; Department of Cardiology, McGill University Health Centre, Montreal, Québec, Canada., Marsh J; The University of Western Australia - Perth Campus, Perth, Western Australia, Australia., Mertz D; Department of Medicine, McMaster University, Hamilton, Ontario, Canada., Paul M; Technion Israel Institute of Technology, Haifa, Israel., Rodriguez-Baño J; Hospital Universitario Virgen Macarena, Seville, Spain., Siegal DM; Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada.; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Tong SY; Department of Infectious Diseases, University of Melbourne, Melbourne, Victoria, Australia., Walls G; Middlemore Hosp, Middlemore, UK., Lee TC; McGill University Health Centre, Montreal, Québec, Canada.
Corporate Authors: SNAP Global Trial Steering Committee
Source: BMJ open [BMJ Open] 2025 Dec 12; Vol. 15 (12), pp. e107493. Date of Electronic Publication: 2025 Dec 12.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2044-6055
DOI:10.1136/bmjopen-2025-107493