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Tissue-specific mutagenesis from endogenous guanine damage is suppressed by Polκ and DNA repair.

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Title: Tissue-specific mutagenesis from endogenous guanine damage is suppressed by Polκ and DNA repair.
Authors: Jiang Y; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands., Przybilla M; Wellcome Sanger Institute, Hinxton, UK., Bakker L; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands., Jacobs FC; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., Mckeon D; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., van der Sluijs R; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands., Sato K; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands., Wezenbeek J; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands., van Strien J; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands., Willems J; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands., Verkennis AEE; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands., Barnett J; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands., Ortega AB; Wellcome Sanger Institute, Hinxton, UK., Abascal F; Wellcome Sanger Institute, Hinxton, UK., Villalta PW; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., Knipscheer P; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands., Martincorena I; Wellcome Sanger Institute, Hinxton, UK., Balbo S; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., Garaycoechea J; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands. juan.g@hubrecht.eu.
Source: Nature communications [Nat Commun] 2025 Dec 12; Vol. 17 (1), pp. 436. Date of Electronic Publication: 2025 Dec 12.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Tissue-specific mutagenesis from endogenous guanine damage is suppressed by Polκ and DNA repair.
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  Data: <searchLink fieldCode="AU" term="%22Jiang+Y%22">Jiang Y</searchLink>; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Przybilla+M%22">Przybilla M</searchLink>; Wellcome Sanger Institute, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Bakker+L%22">Bakker L</searchLink>; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Jacobs+FC%22">Jacobs FC</searchLink>; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Mckeon+D%22">Mckeon D</searchLink>; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22van+der+Sluijs+R%22">van der Sluijs R</searchLink>; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Sato+K%22">Sato K</searchLink>; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Wezenbeek+J%22">Wezenbeek J</searchLink>; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Strien+J%22">van Strien J</searchLink>; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Willems+J%22">Willems J</searchLink>; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Verkennis+AEE%22">Verkennis AEE</searchLink>; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Barnett+J%22">Barnett J</searchLink>; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ortega+AB%22">Ortega AB</searchLink>; Wellcome Sanger Institute, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Abascal+F%22">Abascal F</searchLink>; Wellcome Sanger Institute, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Villalta+PW%22">Villalta PW</searchLink>; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Knipscheer+P%22">Knipscheer P</searchLink>; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Martincorena+I%22">Martincorena I</searchLink>; Wellcome Sanger Institute, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Balbo+S%22">Balbo S</searchLink>; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Garaycoechea+J%22">Garaycoechea J</searchLink>; Hubrecht Institute - KNAW and University Medical Center Utrecht, Utrecht, The Netherlands. juan.g@hubrecht.eu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Dec 12; Vol. 17 (1), pp. 436. <i>Date of Electronic Publication: </i>2025 Dec 12.
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