NRAV promotes HCC stemness via the m6A-regulated let-7c-5p/LIN28B axis.

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Title: NRAV promotes HCC stemness via the m6A-regulated let-7c-5p/LIN28B axis.
Authors: Chen Y; Department of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China., Dai S; Department of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China., Zhuang L; Department of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China., Cai W; Department of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China., Chen H; Department of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China., Zhao J; Department of Oncology, Shaoxing Central Hospital, Shaoxing, China.; Department of Oncology, The Central Affiliated Hospital, Shaoxing University, Shaoxing, China., Zhang F; Oncology Department of Integrated Traditional Chinese and Western Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, China.; Graduate School of Anhui University of Traditional Chinese Medicine, Hefei, China., Chen L; Department of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai, China. lianyu-chen@alu.fudan.edu.cn.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. lianyu-chen@alu.fudan.edu.cn., Cheng CS; Department of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai, China. natcheng@connect.hku.hk.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. natcheng@connect.hku.hk.
Source: Cancer gene therapy [Cancer Gene Ther] 2026 Feb; Vol. 33 (2), pp. 171-185. Date of Electronic Publication: 2025 Dec 12.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9432230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5500 (Electronic) Linking ISSN: 09291903 NLM ISO Abbreviation: Cancer Gene Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5500
DOI:10.1038/s41417-025-00995-5