Evaluating transportability of in vitro cellular models to in vivo human phenotypes using gene perturbation data.

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Bibliographic Details
Title: Evaluating transportability of in vitro cellular models to in vivo human phenotypes using gene perturbation data.
Authors: Howe LJ; GSK, Gunnels Wood Road, Stevenage, United Kingdom. laurence.x.howe@gsk.com., Aulchenko YS; GSK, Gunnels Wood Road, Stevenage, United Kingdom., Davey Smith G; MRC-IEU, University of Bristol, Bristol, UK., Davies NM; Division of Psychiatry, University College London, London, UK., Esparza-Gordillo J; GSK, Calle Severo Ochoa, Tres Cantos, Spain., Johnson T; GSK, Gunnels Wood Road, Stevenage, United Kingdom., Liu JZ; GSK, Collegeville, Collegeville, Pennsylvania, USA., Richardson TG; GSK, Gunnels Wood Road, Stevenage, United Kingdom., Sanseau P; GSK, Gunnels Wood Road, Stevenage, United Kingdom., Scott RA; GSK, Gunnels Wood Road, Stevenage, United Kingdom., Seaton DD; GSK, Gunnels Wood Road, Stevenage, United Kingdom., Sharma A; GSK, Gunnels Wood Road, Stevenage, United Kingdom., Cortes A; GSK, Meyerhofstrasse 1, Heidelberg, Germany.
Source: Nature communications [Nat Commun] 2025 Dec 13; Vol. 17 (1), pp. 513. Date of Electronic Publication: 2025 Dec 13.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-025-67199-1