View in EDS

Evaluating transportability of in vitro cellular models to in vivo human phenotypes using gene perturbation data.

Saved in:
Bibliographic Details
Title: Evaluating transportability of in vitro cellular models to in vivo human phenotypes using gene perturbation data.
Authors: Howe LJ; GSK, Gunnels Wood Road, Stevenage, United Kingdom. laurence.x.howe@gsk.com., Aulchenko YS; GSK, Gunnels Wood Road, Stevenage, United Kingdom., Davey Smith G; MRC-IEU, University of Bristol, Bristol, UK., Davies NM; Division of Psychiatry, University College London, London, UK., Esparza-Gordillo J; GSK, Calle Severo Ochoa, Tres Cantos, Spain., Johnson T; GSK, Gunnels Wood Road, Stevenage, United Kingdom., Liu JZ; GSK, Collegeville, Collegeville, Pennsylvania, USA., Richardson TG; GSK, Gunnels Wood Road, Stevenage, United Kingdom., Sanseau P; GSK, Gunnels Wood Road, Stevenage, United Kingdom., Scott RA; GSK, Gunnels Wood Road, Stevenage, United Kingdom., Seaton DD; GSK, Gunnels Wood Road, Stevenage, United Kingdom., Sharma A; GSK, Gunnels Wood Road, Stevenage, United Kingdom., Cortes A; GSK, Meyerhofstrasse 1, Heidelberg, Germany.
Source: Nature communications [Nat Commun] 2025 Dec 13; Vol. 17 (1), pp. 513. Date of Electronic Publication: 2025 Dec 13.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41390353
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Evaluating transportability of in vitro cellular models to in vivo human phenotypes using gene perturbation data.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Howe+LJ%22">Howe LJ</searchLink>; GSK, Gunnels Wood Road, Stevenage, United Kingdom. laurence.x.howe@gsk.com.<br /><searchLink fieldCode="AU" term="%22Aulchenko+YS%22">Aulchenko YS</searchLink>; GSK, Gunnels Wood Road, Stevenage, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Davey+Smith+G%22">Davey Smith G</searchLink>; MRC-IEU, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Davies+NM%22">Davies NM</searchLink>; Division of Psychiatry, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Esparza-Gordillo+J%22">Esparza-Gordillo J</searchLink>; GSK, Calle Severo Ochoa, Tres Cantos, Spain.<br /><searchLink fieldCode="AU" term="%22Johnson+T%22">Johnson T</searchLink>; GSK, Gunnels Wood Road, Stevenage, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Liu+JZ%22">Liu JZ</searchLink>; GSK, Collegeville, Collegeville, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Richardson+TG%22">Richardson TG</searchLink>; GSK, Gunnels Wood Road, Stevenage, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Sanseau+P%22">Sanseau P</searchLink>; GSK, Gunnels Wood Road, Stevenage, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Scott+RA%22">Scott RA</searchLink>; GSK, Gunnels Wood Road, Stevenage, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Seaton+DD%22">Seaton DD</searchLink>; GSK, Gunnels Wood Road, Stevenage, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Sharma+A%22">Sharma A</searchLink>; GSK, Gunnels Wood Road, Stevenage, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Cortes+A%22">Cortes A</searchLink>; GSK, Meyerhofstrasse 1, Heidelberg, Germany.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Dec 13; Vol. 17 (1), pp. 513. <i>Date of Electronic Publication: </i>2025 Dec 13.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41390353
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41467-025-67199-1
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 513
    Titles:
      – TitleFull: Evaluating transportability of in vitro cellular models to in vivo human phenotypes using gene perturbation data.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Howe LJ
      – PersonEntity:
          Name:
            NameFull: Aulchenko YS
      – PersonEntity:
          Name:
            NameFull: Davey Smith G
      – PersonEntity:
          Name:
            NameFull: Davies NM
      – PersonEntity:
          Name:
            NameFull: Esparza-Gordillo J
      – PersonEntity:
          Name:
            NameFull: Johnson T
      – PersonEntity:
          Name:
            NameFull: Liu JZ
      – PersonEntity:
          Name:
            NameFull: Richardson TG
      – PersonEntity:
          Name:
            NameFull: Sanseau P
      – PersonEntity:
          Name:
            NameFull: Scott RA
      – PersonEntity:
          Name:
            NameFull: Seaton DD
      – PersonEntity:
          Name:
            NameFull: Sharma A
      – PersonEntity:
          Name:
            NameFull: Cortes A
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 13
              M: 12
              Text: 2025 Dec 13
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
          Numbering:
            – Type: volume
              Value: 17
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature communications
              Type: main
ResultId 1