Effect of Systemic Hydrocortisone in Ventilated Infants Born Preterm: Mortality and 5.5-Year Neurodevelopmental Outcomes of a Randomized Clinical Trial.

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Title: Effect of Systemic Hydrocortisone in Ventilated Infants Born Preterm: Mortality and 5.5-Year Neurodevelopmental Outcomes of a Randomized Clinical Trial.
Authors: de Baat T; Department of Neonatology, Emma Children's Hospital, Amsterdam UMC, Amsterdam, The Netherlands; Amsterdam Reproduction & Development research institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands. Electronic address: t.debaat@amsterdamumc.nl., van de Loo M; Department of Neonatology, Emma Children's Hospital, Amsterdam UMC, Amsterdam, The Netherlands; Amsterdam Reproduction & Development research institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Aarnoudse-Moens CSH; Department of Neonatology, Emma Children's Hospital, Amsterdam UMC, Amsterdam, The Netherlands; Amsterdam Reproduction & Development research institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands; Amsterdam UMC location University of Amsterdam, Emma Children's Hospital, Child and Adolescent Psychiatry & Psychosocial Care, Amsterdam, The Netherlands; Amsterdam Reproduction and Development, Child Development and Pregnancy & Birth, Amsterdam Public Health, Mental Health and Societal Participation & Health, Amsterdam, The Netherlands., Halbmeijer NM; Department of Neonatology, Emma Children's Hospital, Amsterdam UMC, Amsterdam, The Netherlands; Amsterdam Reproduction & Development research institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Onland W; Department of Neonatology, Emma Children's Hospital, Amsterdam UMC, Amsterdam, The Netherlands; Amsterdam Reproduction & Development research institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., van Kaam AH; Department of Neonatology, Emma Children's Hospital, Amsterdam UMC, Amsterdam, The Netherlands; Amsterdam Reproduction & Development research institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Koopman C; Department of Neonatology, University Medical Center Utrecht, Utrecht, The Netherlands., Swarte RMC; Division of Neonatology, Department of Paediatric and Neonatal Intensive Care, Erasmus University Medical Centre-Sophia Children's Hospital, Rotterdam, The Netherlands., Mulder-de Tollenaer SM; Department of Neonatology, Isala Medical Center, Zwolle, The Netherlands., van Stuijvenberg M; Department of Neonatology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Tan RNGB; Department of Neonatology, Leiden University Medical Center, Leiden, The Netherlands., de Kort E; Department of Neonatology, Máxima Medical Center, Veldhoven, The Netherlands., Bruneel E; Department of Neonatology, Ziekenhuis Oost-Limburg, Genk, Belgium., Cools F; Department of Neonatology, Universitair Ziekenhuis Brussel, Brussels, Belgium., Steiner K; Department of Neonatology, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands., Debeer A; Department of Neonatology, Universitair Ziekenhuis Leuven, Leuven, Belgium., Van Mechelen K; Department of Neonatology, MosaKids Children's Hospital, Maastricht University Medical Center, Maastricht, The Netherlands., Blom H; Department of Neonatology, Universitair Ziekenhuis Antwerpen, Antwerp, Belgium., Maréchal Y; Department of Neonatology, Centre Hospitalier Universitaire de Charleroi, Charleroi, Belgium., Plaskie K; Department of Neonatology, St Augustinus Ziekenhuis, Antwerp, Belgium., Leemhuis AG; Department of Neonatology, Emma Children's Hospital, Amsterdam UMC, Amsterdam, The Netherlands; Amsterdam Reproduction & Development research institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Corporate Authors: SToP-BPD Trial Collaborators
Source: The Journal of pediatrics [J Pediatr] 2026 Mar; Vol. 290, pp. 114954. Date of Electronic Publication: 2025 Dec 13.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 0375410 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6833 (Electronic) Linking ISSN: 00223476 NLM ISO Abbreviation: J Pediatr Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effect of Systemic Hydrocortisone in Ventilated Infants Born Preterm: Mortality and 5.5-Year Neurodevelopmental Outcomes of a Randomized Clinical Trial.
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  Data: <searchLink fieldCode="AU" term="%22de+Baat+T%22">de Baat T</searchLink>; Department of Neonatology, Emma Children's Hospital, Amsterdam UMC, Amsterdam, The Netherlands; Amsterdam Reproduction & Development research institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands. Electronic address: t.debaat@amsterdamumc.nl.<br /><searchLink fieldCode="AU" term="%22van+de+Loo+M%22">van de Loo M</searchLink>; Department of Neonatology, Emma Children's Hospital, Amsterdam UMC, Amsterdam, The Netherlands; Amsterdam Reproduction & Development research institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Aarnoudse-Moens+CSH%22">Aarnoudse-Moens CSH</searchLink>; Department of Neonatology, Emma Children's Hospital, Amsterdam UMC, Amsterdam, The Netherlands; Amsterdam Reproduction & Development research institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands; Amsterdam UMC location University of Amsterdam, Emma Children's Hospital, Child and Adolescent Psychiatry & Psychosocial Care, Amsterdam, The Netherlands; Amsterdam Reproduction and Development, Child Development and Pregnancy & Birth, Amsterdam Public Health, Mental Health and Societal Participation & Health, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Halbmeijer+NM%22">Halbmeijer NM</searchLink>; Department of Neonatology, Emma Children's Hospital, Amsterdam UMC, Amsterdam, The Netherlands; Amsterdam Reproduction & Development research institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Onland+W%22">Onland W</searchLink>; Department of Neonatology, Emma Children's Hospital, Amsterdam UMC, Amsterdam, The Netherlands; Amsterdam Reproduction & Development research institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Kaam+AH%22">van Kaam AH</searchLink>; Department of Neonatology, Emma Children's Hospital, Amsterdam UMC, Amsterdam, The Netherlands; Amsterdam Reproduction & Development research institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Koopman+C%22">Koopman C</searchLink>; Department of Neonatology, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Swarte+RMC%22">Swarte RMC</searchLink>; Division of Neonatology, Department of Paediatric and Neonatal Intensive Care, Erasmus University Medical Centre-Sophia Children's Hospital, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Mulder-de+Tollenaer+SM%22">Mulder-de Tollenaer SM</searchLink>; Department of Neonatology, Isala Medical Center, Zwolle, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Stuijvenberg+M%22">van Stuijvenberg M</searchLink>; Department of Neonatology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Tan+RNGB%22">Tan RNGB</searchLink>; Department of Neonatology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Kort+E%22">de Kort E</searchLink>; Department of Neonatology, Máxima Medical Center, Veldhoven, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bruneel+E%22">Bruneel E</searchLink>; Department of Neonatology, Ziekenhuis Oost-Limburg, Genk, Belgium.<br /><searchLink fieldCode="AU" term="%22Cools+F%22">Cools F</searchLink>; Department of Neonatology, Universitair Ziekenhuis Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Steiner+K%22">Steiner K</searchLink>; Department of Neonatology, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Debeer+A%22">Debeer A</searchLink>; Department of Neonatology, Universitair Ziekenhuis Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Van+Mechelen+K%22">Van Mechelen K</searchLink>; Department of Neonatology, MosaKids Children's Hospital, Maastricht University Medical Center, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Blom+H%22">Blom H</searchLink>; Department of Neonatology, Universitair Ziekenhuis Antwerpen, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Maréchal+Y%22">Maréchal Y</searchLink>; Department of Neonatology, Centre Hospitalier Universitaire de Charleroi, Charleroi, Belgium.<br /><searchLink fieldCode="AU" term="%22Plaskie+K%22">Plaskie K</searchLink>; Department of Neonatology, St Augustinus Ziekenhuis, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Leemhuis+AG%22">Leemhuis AG</searchLink>; Department of Neonatology, Emma Children's Hospital, Amsterdam UMC, Amsterdam, The Netherlands; Amsterdam Reproduction & Development research institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%220375410%22">The Journal of pediatrics</searchLink> [J Pediatr] 2026 Mar; Vol. 290, pp. 114954. <i>Date of Electronic Publication: </i>2025 Dec 13.
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