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Hypoxia-activated HSP90AA1/STUB1 axis promotes acute pancreatitis via necroptosis protein stabilization.

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Title: Hypoxia-activated HSP90AA1/STUB1 axis promotes acute pancreatitis via necroptosis protein stabilization.
Authors: Song TJ; Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, China; Department of Emergency, Fujian Provincial Hospital, Fuzhou, 350001, China; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China; Fujian Provincial Key Laboratory of Emergency Medicine, Fuzhou, 350001, China., Zhu CS; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China., Luo JQ; The Graduate School of Fujian Medical University (Jin nan Branch of Jinjiang Hospital), Jin jiang, 362241, China., Chen H; Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, China; Department of Emergency, Fujian Provincial Hospital, Fuzhou, 350001, China; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China; Fujian Provincial Key Laboratory of Emergency Medicine, Fuzhou, 350001, China., Chen LX; Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, China; Department of Emergency, Fujian Provincial Hospital, Fuzhou, 350001, China; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China; Fujian Provincial Key Laboratory of Emergency Medicine, Fuzhou, 350001, China., Chen HY; Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, China; Department of Emergency, Fujian Provincial Hospital, Fuzhou, 350001, China; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China; Fujian Provincial Key Laboratory of Emergency Medicine, Fuzhou, 350001, China., Ke J; Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, China; Department of Emergency, Fujian Provincial Hospital, Fuzhou, 350001, China; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China; Fujian Provincial Key Laboratory of Emergency Medicine, Fuzhou, 350001, China. Electronic address: drkejun@fjmu.edu.cn., Lin SR; Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, China; Department of Emergency, Fujian Provincial Hospital, Fuzhou, 350001, China; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China; Fujian Provincial Key Laboratory of Emergency Medicine, Fuzhou, 350001, China. Electronic address: leopard862@fjmu.edu.cn., Chen F; Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, China; Department of Emergency, Fujian Provincial Hospital, Fuzhou, 350001, China; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China; Fujian Provincial Key Laboratory of Emergency Medicine, Fuzhou, 350001, China. Electronic address: drchenfeng@fjmu.edu.cn.
Source: Life sciences [Life Sci] 2026 Feb 01; Vol. 386, pp. 124149. Date of Electronic Publication: 2025 Dec 12.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Hypoxia-activated HSP90AA1/STUB1 axis promotes acute pancreatitis via necroptosis protein stabilization.
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  Data: <searchLink fieldCode="AU" term="%22Song+TJ%22">Song TJ</searchLink>; Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, China; Department of Emergency, Fujian Provincial Hospital, Fuzhou, 350001, China; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China; Fujian Provincial Key Laboratory of Emergency Medicine, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Zhu+CS%22">Zhu CS</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Luo+JQ%22">Luo JQ</searchLink>; The Graduate School of Fujian Medical University (Jin nan Branch of Jinjiang Hospital), Jin jiang, 362241, China.<br /><searchLink fieldCode="AU" term="%22Chen+H%22">Chen H</searchLink>; Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, China; Department of Emergency, Fujian Provincial Hospital, Fuzhou, 350001, China; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China; Fujian Provincial Key Laboratory of Emergency Medicine, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Chen+LX%22">Chen LX</searchLink>; Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, China; Department of Emergency, Fujian Provincial Hospital, Fuzhou, 350001, China; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China; Fujian Provincial Key Laboratory of Emergency Medicine, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Chen+HY%22">Chen HY</searchLink>; Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, China; Department of Emergency, Fujian Provincial Hospital, Fuzhou, 350001, China; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China; Fujian Provincial Key Laboratory of Emergency Medicine, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Ke+J%22">Ke J</searchLink>; Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, China; Department of Emergency, Fujian Provincial Hospital, Fuzhou, 350001, China; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China; Fujian Provincial Key Laboratory of Emergency Medicine, Fuzhou, 350001, China. Electronic address: drkejun@fjmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Lin+SR%22">Lin SR</searchLink>; Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, China; Department of Emergency, Fujian Provincial Hospital, Fuzhou, 350001, China; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China; Fujian Provincial Key Laboratory of Emergency Medicine, Fuzhou, 350001, China. Electronic address: leopard862@fjmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Chen+F%22">Chen F</searchLink>; Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, China; Department of Emergency, Fujian Provincial Hospital, Fuzhou, 350001, China; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China; Fujian Provincial Key Laboratory of Emergency Medicine, Fuzhou, 350001, China. Electronic address: drchenfeng@fjmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%220375521%22">Life sciences</searchLink> [Life Sci] 2026 Feb 01; Vol. 386, pp. 124149. <i>Date of Electronic Publication: </i>2025 Dec 12.
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        Value: 10.1016/j.lfs.2025.124149
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        Text: English
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      – TitleFull: Hypoxia-activated HSP90AA1/STUB1 axis promotes acute pancreatitis via necroptosis protein stabilization.
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              Text: 2026 Feb 01
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              Y: 2026
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