View in EDS

In vivo-measured Lewy body pathology is associated with neuropsychiatric symptoms across the Alzheimer's disease continuum.

Saved in:
Bibliographic Details
Title: In vivo-measured Lewy body pathology is associated with neuropsychiatric symptoms across the Alzheimer's disease continuum.
Authors: Leffa DT; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA. teixeiraleffad@upmc.edu., Povala G; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA., Ferreira PCL; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA., Ferrari-Souza JP; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, 2600 Ramiro Barcelos, Porto Alegre, RS, 90035-003, Brazil., Bauer-Negrini G; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA., Rodrigues MS; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA., Amaral L; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA., Lussier FZ; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA., Medeiros MS; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA.; Brain Institute of Rio Grande do Sul, Pontifical Catholic University of Rio Grande do Sul, 6690 Avenida Ipiranga, Porto Alegre, RS, 90035-003, Brazil., Soares C; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA., Aguzzoli CS; Brain Institute of Rio Grande do Sul, Pontifical Catholic University of Rio Grande do Sul, 6690 Avenida Ipiranga, Porto Alegre, RS, 90035-003, Brazil., Macedo AC; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, McConnell Brain Imaging Centre (BIC), Montreal Neurological Institute, Montreal Neurological Institute-Hospital, 3801 Rue University, Montréal, QC, H3A 2B4, Canada., Therriault J; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, McConnell Brain Imaging Centre (BIC), Montreal Neurological Institute, Montreal Neurological Institute-Hospital, 3801 Rue University, Montréal, QC, H3A 2B4, Canada., Rosa-Neto P; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, McConnell Brain Imaging Centre (BIC), Montreal Neurological Institute, Montreal Neurological Institute-Hospital, 3801 Rue University, Montréal, QC, H3A 2B4, Canada.; The Peter O'Donnell Jr. Brain Institute (OBI), University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75235, USA.; Institution: Douglas Hospital Research Centre, Centre intégré universitaire de santé et services sociaux de l'Ouest-de-l'Île-de-Montréal, Verdun, QC, H4H 1R3, Canada., Tudorascu DL; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA., Zimmer ER; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, 2600 Ramiro Barcelos, Porto Alegre, RS, 90035-003, Brazil.; Graduate Program in Biological Sciences: Pharmacology and Therapeutics, Department of Pharmacology, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos 2600, Porto Alegre, RS, 90050-170, Brazil.; Department of Pharmacology and Therapeutics, McGill University, 3655 Promenade Sir William Osler, Montréal, QC, H3G 1Y6, Canada.; Hospital Moinhos de Vento, Porto Alegre, Brazil., Bellaver B; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA., Pascoal TA; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA. pascoalt@upmc.edu.; Department of Neurology, University of Pittsburgh, 3471 Fifth Avenue, Pittsburgh, PA, 15213, USA. pascoalt@upmc.edu.
Source: Molecular psychiatry [Mol Psychiatry] 2026 May; Vol. 31 (5), pp. 2472-2480. Date of Electronic Publication: 2025 Dec 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41392092
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: In vivo-measured Lewy body pathology is associated with neuropsychiatric symptoms across the Alzheimer's disease continuum.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Leffa+DT%22">Leffa DT</searchLink>; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA. teixeiraleffad@upmc.edu.<br /><searchLink fieldCode="AU" term="%22Povala+G%22">Povala G</searchLink>; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA.<br /><searchLink fieldCode="AU" term="%22Ferreira+PCL%22">Ferreira PCL</searchLink>; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA.<br /><searchLink fieldCode="AU" term="%22Ferrari-Souza+JP%22">Ferrari-Souza JP</searchLink>; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, 2600 Ramiro Barcelos, Porto Alegre, RS, 90035-003, Brazil.<br /><searchLink fieldCode="AU" term="%22Bauer-Negrini+G%22">Bauer-Negrini G</searchLink>; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA.<br /><searchLink fieldCode="AU" term="%22Rodrigues+MS%22">Rodrigues MS</searchLink>; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA.<br /><searchLink fieldCode="AU" term="%22Amaral+L%22">Amaral L</searchLink>; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA.<br /><searchLink fieldCode="AU" term="%22Lussier+FZ%22">Lussier FZ</searchLink>; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA.<br /><searchLink fieldCode="AU" term="%22Medeiros+MS%22">Medeiros MS</searchLink>; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA.; Brain Institute of Rio Grande do Sul, Pontifical Catholic University of Rio Grande do Sul, 6690 Avenida Ipiranga, Porto Alegre, RS, 90035-003, Brazil.<br /><searchLink fieldCode="AU" term="%22Soares+C%22">Soares C</searchLink>; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA.<br /><searchLink fieldCode="AU" term="%22Aguzzoli+CS%22">Aguzzoli CS</searchLink>; Brain Institute of Rio Grande do Sul, Pontifical Catholic University of Rio Grande do Sul, 6690 Avenida Ipiranga, Porto Alegre, RS, 90035-003, Brazil.<br /><searchLink fieldCode="AU" term="%22Macedo+AC%22">Macedo AC</searchLink>; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, McConnell Brain Imaging Centre (BIC), Montreal Neurological Institute, Montreal Neurological Institute-Hospital, 3801 Rue University, Montréal, QC, H3A 2B4, Canada.<br /><searchLink fieldCode="AU" term="%22Therriault+J%22">Therriault J</searchLink>; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, McConnell Brain Imaging Centre (BIC), Montreal Neurological Institute, Montreal Neurological Institute-Hospital, 3801 Rue University, Montréal, QC, H3A 2B4, Canada.<br /><searchLink fieldCode="AU" term="%22Rosa-Neto+P%22">Rosa-Neto P</searchLink>; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, McConnell Brain Imaging Centre (BIC), Montreal Neurological Institute, Montreal Neurological Institute-Hospital, 3801 Rue University, Montréal, QC, H3A 2B4, Canada.; The Peter O'Donnell Jr. Brain Institute (OBI), University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75235, USA.; Institution: Douglas Hospital Research Centre, Centre intégré universitaire de santé et services sociaux de l'Ouest-de-l'Île-de-Montréal, Verdun, QC, H4H 1R3, Canada.<br /><searchLink fieldCode="AU" term="%22Tudorascu+DL%22">Tudorascu DL</searchLink>; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA.<br /><searchLink fieldCode="AU" term="%22Zimmer+ER%22">Zimmer ER</searchLink>; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, 2600 Ramiro Barcelos, Porto Alegre, RS, 90035-003, Brazil.; Graduate Program in Biological Sciences: Pharmacology and Therapeutics, Department of Pharmacology, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos 2600, Porto Alegre, RS, 90050-170, Brazil.; Department of Pharmacology and Therapeutics, McGill University, 3655 Promenade Sir William Osler, Montréal, QC, H3G 1Y6, Canada.; Hospital Moinhos de Vento, Porto Alegre, Brazil.<br /><searchLink fieldCode="AU" term="%22Bellaver+B%22">Bellaver B</searchLink>; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA.<br /><searchLink fieldCode="AU" term="%22Pascoal+TA%22">Pascoal TA</searchLink>; Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA, 15213, USA. pascoalt@upmc.edu.; Department of Neurology, University of Pittsburgh, 3471 Fifth Avenue, Pittsburgh, PA, 15213, USA. pascoalt@upmc.edu.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%229607835%22">Molecular psychiatry</searchLink> [Mol Psychiatry] 2026 May; Vol. 31 (5), pp. 2472-2480. <i>Date of Electronic Publication: </i>2025 Dec 14.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+Specialist+Journals%22">Nature Publishing Group Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9607835 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5578 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213594184%22">13594184 </searchLink><i>NLM ISO Abbreviation: </i>Mol Psychiatry <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41392092
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41380-025-03400-7
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 2472
    Titles:
      – TitleFull: In vivo-measured Lewy body pathology is associated with neuropsychiatric symptoms across the Alzheimer's disease continuum.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Leffa DT
      – PersonEntity:
          Name:
            NameFull: Povala G
      – PersonEntity:
          Name:
            NameFull: Ferreira PCL
      – PersonEntity:
          Name:
            NameFull: Ferrari-Souza JP
      – PersonEntity:
          Name:
            NameFull: Bauer-Negrini G
      – PersonEntity:
          Name:
            NameFull: Rodrigues MS
      – PersonEntity:
          Name:
            NameFull: Amaral L
      – PersonEntity:
          Name:
            NameFull: Lussier FZ
      – PersonEntity:
          Name:
            NameFull: Medeiros MS
      – PersonEntity:
          Name:
            NameFull: Soares C
      – PersonEntity:
          Name:
            NameFull: Aguzzoli CS
      – PersonEntity:
          Name:
            NameFull: Macedo AC
      – PersonEntity:
          Name:
            NameFull: Therriault J
      – PersonEntity:
          Name:
            NameFull: Rosa-Neto P
      – PersonEntity:
          Name:
            NameFull: Tudorascu DL
      – PersonEntity:
          Name:
            NameFull: Zimmer ER
      – PersonEntity:
          Name:
            NameFull: Bellaver B
      – PersonEntity:
          Name:
            NameFull: Pascoal TA
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 05
              Text: 2026 May
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1476-5578
          Numbering:
            – Type: volume
              Value: 31
            – Type: issue
              Value: 5
          Titles:
            – TitleFull: Molecular psychiatry
              Type: main
ResultId 1