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A clinical-stage oncology compound selectively targets drug-resistant cancers.

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Title: A clinical-stage oncology compound selectively targets drug-resistant cancers.
Authors: Long K; Stanford University School of Medicine, Stanford, California 94305, USA., Bhattacharjee D; Stanford University School of Medicine, Stanford, California 94305, USA., Newman-Stonebraker SH; Yale University School of Medicine, New Haven, Connecticut 06511, USA., Suhr S; Yale University School of Medicine, New Haven, Connecticut 06511, USA., Mercado BQ; Yale University School of Medicine, New Haven, Connecticut 06511, USA., Scheib E; Laboratory of Membrane Biology and Biophysics, The Rockefeller University, New York, NY 10065, USA., Tighe A; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Cancer Research Centre, 555 Wilmslow Road, Manchester M20 4GJ, UK., Romero L; Yale University School of Medicine, New Haven, Connecticut 06511, USA., Thompson SL; Stanford University School of Medicine, Stanford, California 94305, USA., Sausville EL; Yale University School of Medicine, New Haven, Connecticut 06511, USA., John KM; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA., Julian L; Yale University School of Medicine, New Haven, Connecticut 06511, USA., Mishra S; Stanford University School of Medicine, Stanford, California 94305, USA., Klingbeil O; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.; Laboratory for Functional Genomics and Gene Regulation, Center for Cancer Biology, VIB, Leuven, Belgium.; Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Gupta P; Stanford University School of Medicine, Stanford, California 94305, USA., Bhatt U; University Hospital Zurich, 8032 Zürich, CH., Gao AC; University of California Davis, Sacramento, California 95817, USA., Ricardo S; Applied Molecular Biosciences Unit (UCIBIO), Toxicologic Pathology Research Laboratory, Institute of Health Sciences (IUCS), Cooperativa de Ensino Superior Politécnico e Universitário (CESPU), 4585-116 Gandra, Portugal.; Associate Laboratory i4HB, Institute for Health and Bioeconomy, University Institute of Health Sciences (IUCS), University Polytechnic Higher Education Cooperative (CESPU), CRL, 4585-116 Gandra, Portugal., Vakoc CR; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA., Bornhauser BC; University Hospital Zurich, 8032 Zürich, CH., Corsello SM; Stanford University School of Medicine, Stanford, California 94305, USA., Taylor SS; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Cancer Research Centre, 555 Wilmslow Road, Manchester M20 4GJ, UK., Chen J; Laboratory of Membrane Biology and Biophysics, The Rockefeller University, New York, NY 10065, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA., Holland PL; Yale University School of Medicine, New Haven, Connecticut 06511, USA., Sheltzer JM; Stanford University School of Medicine, Stanford, California 94305, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Feb 03. Date of Electronic Publication: 2026 Feb 03.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
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DbLabel: MEDLINE Ultimate
An: 41394735
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: A clinical-stage oncology compound selectively targets drug-resistant cancers.
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  Data: <searchLink fieldCode="AU" term="%22Long+K%22">Long K</searchLink>; Stanford University School of Medicine, Stanford, California 94305, USA.<br /><searchLink fieldCode="AU" term="%22Bhattacharjee+D%22">Bhattacharjee D</searchLink>; Stanford University School of Medicine, Stanford, California 94305, USA.<br /><searchLink fieldCode="AU" term="%22Newman-Stonebraker+SH%22">Newman-Stonebraker SH</searchLink>; Yale University School of Medicine, New Haven, Connecticut 06511, USA.<br /><searchLink fieldCode="AU" term="%22Suhr+S%22">Suhr S</searchLink>; Yale University School of Medicine, New Haven, Connecticut 06511, USA.<br /><searchLink fieldCode="AU" term="%22Mercado+BQ%22">Mercado BQ</searchLink>; Yale University School of Medicine, New Haven, Connecticut 06511, USA.<br /><searchLink fieldCode="AU" term="%22Scheib+E%22">Scheib E</searchLink>; Laboratory of Membrane Biology and Biophysics, The Rockefeller University, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Tighe+A%22">Tighe A</searchLink>; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Cancer Research Centre, 555 Wilmslow Road, Manchester M20 4GJ, UK.<br /><searchLink fieldCode="AU" term="%22Romero+L%22">Romero L</searchLink>; Yale University School of Medicine, New Haven, Connecticut 06511, USA.<br /><searchLink fieldCode="AU" term="%22Thompson+SL%22">Thompson SL</searchLink>; Stanford University School of Medicine, Stanford, California 94305, USA.<br /><searchLink fieldCode="AU" term="%22Sausville+EL%22">Sausville EL</searchLink>; Yale University School of Medicine, New Haven, Connecticut 06511, USA.<br /><searchLink fieldCode="AU" term="%22John+KM%22">John KM</searchLink>; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.<br /><searchLink fieldCode="AU" term="%22Julian+L%22">Julian L</searchLink>; Yale University School of Medicine, New Haven, Connecticut 06511, USA.<br /><searchLink fieldCode="AU" term="%22Mishra+S%22">Mishra S</searchLink>; Stanford University School of Medicine, Stanford, California 94305, USA.<br /><searchLink fieldCode="AU" term="%22Klingbeil+O%22">Klingbeil O</searchLink>; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.; Laboratory for Functional Genomics and Gene Regulation, Center for Cancer Biology, VIB, Leuven, Belgium.; Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Gupta+P%22">Gupta P</searchLink>; Stanford University School of Medicine, Stanford, California 94305, USA.<br /><searchLink fieldCode="AU" term="%22Bhatt+U%22">Bhatt U</searchLink>; University Hospital Zurich, 8032 Zürich, CH.<br /><searchLink fieldCode="AU" term="%22Gao+AC%22">Gao AC</searchLink>; University of California Davis, Sacramento, California 95817, USA.<br /><searchLink fieldCode="AU" term="%22Ricardo+S%22">Ricardo S</searchLink>; Applied Molecular Biosciences Unit (UCIBIO), Toxicologic Pathology Research Laboratory, Institute of Health Sciences (IUCS), Cooperativa de Ensino Superior Politécnico e Universitário (CESPU), 4585-116 Gandra, Portugal.; Associate Laboratory i4HB, Institute for Health and Bioeconomy, University Institute of Health Sciences (IUCS), University Polytechnic Higher Education Cooperative (CESPU), CRL, 4585-116 Gandra, Portugal.<br /><searchLink fieldCode="AU" term="%22Vakoc+CR%22">Vakoc CR</searchLink>; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.<br /><searchLink fieldCode="AU" term="%22Bornhauser+BC%22">Bornhauser BC</searchLink>; University Hospital Zurich, 8032 Zürich, CH.<br /><searchLink fieldCode="AU" term="%22Corsello+SM%22">Corsello SM</searchLink>; Stanford University School of Medicine, Stanford, California 94305, USA.<br /><searchLink fieldCode="AU" term="%22Taylor+SS%22">Taylor SS</searchLink>; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Cancer Research Centre, 555 Wilmslow Road, Manchester M20 4GJ, UK.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Laboratory of Membrane Biology and Biophysics, The Rockefeller University, New York, NY 10065, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.<br /><searchLink fieldCode="AU" term="%22Holland+PL%22">Holland PL</searchLink>; Yale University School of Medicine, New Haven, Connecticut 06511, USA.<br /><searchLink fieldCode="AU" term="%22Sheltzer+JM%22">Sheltzer JM</searchLink>; Stanford University School of Medicine, Stanford, California 94305, USA.
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