Novel immunotheranostic FAP-inhibitor target modules for imaging and elimination of FAP-positive cells by UniCAR T-cells.

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Title: Novel immunotheranostic FAP-inhibitor target modules for imaging and elimination of FAP-positive cells by UniCAR T-cells.
Authors: Boutier H; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany., Kogler J; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; TUD Dresden University of Technology, School of Science, Faculty of Chemistry and Food Chemistry, Dresden, Germany., Loureiro LR; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany., Neuber C; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany., Berndt N; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany., Arndt C; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; Mildred Scheel Early Career Center, Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany., Stadlbauer S; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; TUD Dresden University of Technology, School of Science, Faculty of Chemistry and Food Chemistry, Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden, Germany., Stephan H; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany., Feldmann A; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden, Germany.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology & Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Germany., Kopka K; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; TUD Dresden University of Technology, School of Science, Faculty of Chemistry and Food Chemistry, Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden, Germany.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology & Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Germany., Hagemeyer CE; Australian Centre for Blood Diseases, School of Translational Medicine, Monash University, Melbourne, Victoria, Australia., Bachmann M; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden, Germany.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology & Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Germany.; Faculty of Medicine and University Hospital Carl Gustav Carus, TUD, Dresden, Germany.
Source: Oncoimmunology [Oncoimmunology] 2025 Dec 31; Vol. 14 (1), pp. 2598908. Date of Electronic Publication: 2025 Dec 15.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101570526 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2162-402X (Electronic) Linking ISSN: 21624011 NLM ISO Abbreviation: Oncoimmunology Subsets: MEDLINE
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  Data: Novel immunotheranostic FAP-inhibitor target modules for imaging and elimination of FAP-positive cells by UniCAR T-cells.
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  Data: <searchLink fieldCode="AU" term="%22Boutier+H%22">Boutier H</searchLink>; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Kogler+J%22">Kogler J</searchLink>; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; TUD Dresden University of Technology, School of Science, Faculty of Chemistry and Food Chemistry, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Loureiro+LR%22">Loureiro LR</searchLink>; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Neuber+C%22">Neuber C</searchLink>; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Berndt+N%22">Berndt N</searchLink>; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Arndt+C%22">Arndt C</searchLink>; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; Mildred Scheel Early Career Center, Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Stadlbauer+S%22">Stadlbauer S</searchLink>; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; TUD Dresden University of Technology, School of Science, Faculty of Chemistry and Food Chemistry, Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Stephan+H%22">Stephan H</searchLink>; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Feldmann+A%22">Feldmann A</searchLink>; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden, Germany.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology & Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Germany.<br /><searchLink fieldCode="AU" term="%22Kopka+K%22">Kopka K</searchLink>; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; TUD Dresden University of Technology, School of Science, Faculty of Chemistry and Food Chemistry, Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden, Germany.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology & Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Germany.<br /><searchLink fieldCode="AU" term="%22Hagemeyer+CE%22">Hagemeyer CE</searchLink>; Australian Centre for Blood Diseases, School of Translational Medicine, Monash University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Bachmann+M%22">Bachmann M</searchLink>; Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden, Germany.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology & Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Germany.; Faculty of Medicine and University Hospital Carl Gustav Carus, TUD, Dresden, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101570526%22">Oncoimmunology</searchLink> [Oncoimmunology] 2025 Dec 31; Vol. 14 (1), pp. 2598908. <i>Date of Electronic Publication: </i>2025 Dec 15.
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