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Lipoic Acid for Treatment of Progressive Multiple Sclerosis: A Phase 2 Randomized Clinical Trial.

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Title: Lipoic Acid for Treatment of Progressive Multiple Sclerosis: A Phase 2 Randomized Clinical Trial.
Authors: Spain RI; Department of VA, VA Portland Health Care System, OR.; Department of Neurology, Oregon Health & Science University, Portland, OR., Paz Soldán MM; Department of Veterans Affairs, VA Salt Lake City Health Care System, UT.; Department of Neurology, University of Utah, Salt Lake City., Freedman MS; Department of Medicine and the Ottawa Hospital Research Institute, University of Ottawa, ON, Canada., Repovic P; Department of Neurology, Swedish Medical Center, Seattle, WA., Solomon AJ; Larner College of Medicine, University of Vermont, Burlington., Rinker JR; Department of Neurology, University of Alabama at Birmingham., Wallin MT; Department of Veterans Affairs, VA Washington DC Medical Center.; School of Medicine, University of Maryland, Baltimore, MD., Haselkorn JK; Department of Veterans Affairs, VA Puget Sound Health Care System, Seattle, WA.; Rehabilitation Medicine, University of Washington.; Department of Epidemiology, University of Washington, Seattle., Stuve O; Department of Veterans Affairs, North Texas Health Care System-Dallas.; Department of Neurology, University of Texas Southwestern Medical Center, Dallas.; Peter O'Donnell Brain Institute, University of Texas Southwestern Medical Center, Dallas., Gross RH; Department of Neurology, University of Colorado Anschutz Medical Campus, Aurora, CO., Waslo CS; Department of VA, VA Portland Health Care System, OR.; Department of Neurology, Oregon Health & Science University, Portland, OR., Hildebrand A; Biostatistics & Design Program, Oregon Health & Science University, Portland., Morris CD; Oregon Clinical and Translational Research Institute, Oregon Health & Science University, Portland; and., Mitchell J; Oregon Clinical and Translational Research Institute, Oregon Health & Science University, Portland; and., Turner AP; Department of Veterans Affairs, VA Puget Sound Health Care System, Seattle, WA.; Rehabilitation Medicine, University of Washington., Schwartz DL; Department of Neurology, Oregon Health & Science University, Portland, OR.; Advanced Imaging Research Center, Oregon Health & Science University, Portland., Metz J; Oregon Clinical and Translational Research Institute, Oregon Health & Science University, Portland; and., Rooney W; Advanced Imaging Research Center, Oregon Health & Science University, Portland.
Source: Neurology [Neurology] 2026 Jan 13; Vol. 106 (1), pp. e214454. Date of Electronic Publication: 2025 Dec 15.
Publication Type: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0401060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-632X (Electronic) Linking ISSN: 00283878 NLM ISO Abbreviation: Neurology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Lipoic Acid for Treatment of Progressive Multiple Sclerosis: A Phase 2 Randomized Clinical Trial.
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  Data: <searchLink fieldCode="AU" term="%22Spain+RI%22">Spain RI</searchLink>; Department of VA, VA Portland Health Care System, OR.; Department of Neurology, Oregon Health & Science University, Portland, OR.<br /><searchLink fieldCode="AU" term="%22Paz+Soldán+MM%22">Paz Soldán MM</searchLink>; Department of Veterans Affairs, VA Salt Lake City Health Care System, UT.; Department of Neurology, University of Utah, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Freedman+MS%22">Freedman MS</searchLink>; Department of Medicine and the Ottawa Hospital Research Institute, University of Ottawa, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Repovic+P%22">Repovic P</searchLink>; Department of Neurology, Swedish Medical Center, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Solomon+AJ%22">Solomon AJ</searchLink>; Larner College of Medicine, University of Vermont, Burlington.<br /><searchLink fieldCode="AU" term="%22Rinker+JR%22">Rinker JR</searchLink>; Department of Neurology, University of Alabama at Birmingham.<br /><searchLink fieldCode="AU" term="%22Wallin+MT%22">Wallin MT</searchLink>; Department of Veterans Affairs, VA Washington DC Medical Center.; School of Medicine, University of Maryland, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Haselkorn+JK%22">Haselkorn JK</searchLink>; Department of Veterans Affairs, VA Puget Sound Health Care System, Seattle, WA.; Rehabilitation Medicine, University of Washington.; Department of Epidemiology, University of Washington, Seattle.<br /><searchLink fieldCode="AU" term="%22Stuve+O%22">Stuve O</searchLink>; Department of Veterans Affairs, North Texas Health Care System-Dallas.; Department of Neurology, University of Texas Southwestern Medical Center, Dallas.; Peter O'Donnell Brain Institute, University of Texas Southwestern Medical Center, Dallas.<br /><searchLink fieldCode="AU" term="%22Gross+RH%22">Gross RH</searchLink>; Department of Neurology, University of Colorado Anschutz Medical Campus, Aurora, CO.<br /><searchLink fieldCode="AU" term="%22Waslo+CS%22">Waslo CS</searchLink>; Department of VA, VA Portland Health Care System, OR.; Department of Neurology, Oregon Health & Science University, Portland, OR.<br /><searchLink fieldCode="AU" term="%22Hildebrand+A%22">Hildebrand A</searchLink>; Biostatistics & Design Program, Oregon Health & Science University, Portland.<br /><searchLink fieldCode="AU" term="%22Morris+CD%22">Morris CD</searchLink>; Oregon Clinical and Translational Research Institute, Oregon Health & Science University, Portland; and.<br /><searchLink fieldCode="AU" term="%22Mitchell+J%22">Mitchell J</searchLink>; Oregon Clinical and Translational Research Institute, Oregon Health & Science University, Portland; and.<br /><searchLink fieldCode="AU" term="%22Turner+AP%22">Turner AP</searchLink>; Department of Veterans Affairs, VA Puget Sound Health Care System, Seattle, WA.; Rehabilitation Medicine, University of Washington.<br /><searchLink fieldCode="AU" term="%22Schwartz+DL%22">Schwartz DL</searchLink>; Department of Neurology, Oregon Health & Science University, Portland, OR.; Advanced Imaging Research Center, Oregon Health & Science University, Portland.<br /><searchLink fieldCode="AU" term="%22Metz+J%22">Metz J</searchLink>; Oregon Clinical and Translational Research Institute, Oregon Health & Science University, Portland; and.<br /><searchLink fieldCode="AU" term="%22Rooney+W%22">Rooney W</searchLink>; Advanced Imaging Research Center, Oregon Health & Science University, Portland.
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  Data: <searchLink fieldCode="JN" term="%220401060%22">Neurology</searchLink> [Neurology] 2026 Jan 13; Vol. 106 (1), pp. e214454. <i>Date of Electronic Publication: </i>2025 Dec 15.
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  Data: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial; Multicenter Study
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott+Williams+%26+Wilkins%22">Lippincott Williams & Wilkins </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0401060 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1526-632X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200283878%22">00283878 </searchLink><i>NLM ISO Abbreviation: </i>Neurology <i>Subsets: </i>MEDLINE
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