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Effect of Interventions Aimed at Reducing or Modifying Saturated Fat Intake on Cholesterol, Mortality, and Major Cardiovascular Events : A Risk Stratified Systematic Review of Randomized Trials.

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Title: Effect of Interventions Aimed at Reducing or Modifying Saturated Fat Intake on Cholesterol, Mortality, and Major Cardiovascular Events : A Risk Stratified Systematic Review of Randomized Trials.
Authors: Steen JP; Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada (J.P.S.)., Klatt KC; Department of Nutrition Sciences and Toxicology, University of California, Berkeley, California; and Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada (K.C.K.)., Chang Y; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada (Y.C.)., Guyatt GH; Department of Health Research Methods, Evidence, and Impact and Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada; and MAGIC Evidence Ecosystem Foundation, Oslo, Norway (G.H.G.)., Zhu H; School of Public Health and NHC Key Laboratory of Health Technology Assessment, Fudan University, Shanghai, China (H.Z.)., Swierz MJ; Department of Hygiene and Dietetics, Chair of Epidemiology and Preventive Medicine, Faculty of Medicine, and Systematic Reviews Unit, Jagiellonian University Medical College, Kraków, Poland (M.J.S., D.S., M.M.B.)., Storman D; Department of Hygiene and Dietetics, Chair of Epidemiology and Preventive Medicine, Faculty of Medicine, and Systematic Reviews Unit, Jagiellonian University Medical College, Kraków, Poland (M.J.S., D.S., M.M.B.)., Sun M; School of Nursing, Peking University, Beijing, China (M.S.)., Zhao Y; Department of Geriatric Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China (Y.Z.)., Ge L; Department of Health Policy and Health Management, School of Public Health, Lanzhou University, Lanzhou, China (L.G.)., Thabane L; Department of Health Research Methods, Evidence, and Impact, McMaster University, and Research Institute of St. Joe's Hamilton, St. Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada; and Faculty of Health Sciences, University of Johannesburg, Johannesburg, South Africa (L.T.)., Ghosh NR; Department of Nutrition, College of Agriculture and Life Sciences, Texas A&M University, College Station, Texas (N.R.G.)., Karam G; Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada (G.K.)., Alonso-Coello P; Institut de Recerca Sant Pau (IR Sant Pau) and Iberoamerican Cochrane Center, Hospital de la Santa Creu i Sant Pau, Barcelona, and CIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (P.A.-C.)., Bala MM; Department of Hygiene and Dietetics, Chair of Epidemiology and Preventive Medicine, Faculty of Medicine, and Systematic Reviews Unit, Jagiellonian University Medical College, Kraków, Poland (M.J.S., D.S., M.M.B.)., Johnston BC; Department of Nutrition, College of Agriculture and Life Sciences, and Department of Epidemiology and Biostatistics, School of Public Health, Texas A&M University, College Station, Texas (B.C.J.).
Source: Annals of internal medicine [Ann Intern Med] 2026 Feb; Vol. 179 (2), pp. 242-255. Date of Electronic Publication: 2025 Dec 16.
Publication Type: Journal Article; Systematic Review; Review
Journal Info: Publisher: American College of Physicians--American Society of Internal Medicine Country of Publication: United States NLM ID: 0372351 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1539-3704 (Electronic) Linking ISSN: 00034819 NLM ISO Abbreviation: Ann Intern Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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