Higher HLA-DRB1 Evolutionary Divergence Is Associated with Reduced Relapse and Improved Survival after Matched Unrelated Hematopoietic Cell Transplantation.

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Title: Higher HLA-DRB1 Evolutionary Divergence Is Associated with Reduced Relapse and Improved Survival after Matched Unrelated Hematopoietic Cell Transplantation.
Authors: Saultz JN; Division of Hematology/Oncology, Oregon Health & Sciences University Portland, Oregon. Electronic address: saultzje@ohsu.edu., Bolon YT; Center for International Blood and Marrow Transplant Research, NMDP, Minneapolis, Minnesota., Wang T; Division of Biostatistics, Data Science Institute, Medical College of Wisconsin, Milwaukee, Wisconsin; Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, Wisconsin., Spellman SR; Center for International Blood and Marrow Transplant Research, NMDP, Minneapolis, Minnesota., Lee SJ; Fred Hutchinson Cancer Center, Seattle, Washington., He M; Center for International Blood and Marrow Transplant Research, NMDP, Minneapolis, Minnesota., Camacho-Bydume C; Hackensack University Medical Center, Hackensack, New Jersey., Krishna C; Broad Institute of MIT, Harvard Cambridge, Massachusetts., Chowell D; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York., Shaffer BC; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York; Weill Cornell Medical College, New York, New York., Hsu KC; Weill Cornell Medical College, New York, New York; Immunology Program, Sloan Kettering Institute for Cancer Research, New York, New York., Paczesny S; Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina., Gadalla SM; Division of Cancer Epidemiology and Genetics, National Institutes of Health, National Cancer Institute, Clinical Genetics Branch, Rockville, Maryland., Marsh SGE; University College London Cancer Institute, Royal Free Campus, London, United Kingdom., Betts BC; Roswell Park Cancer Institute, Buffalo, New York., Arrieta-Bolaños E; Institute for Experimental Cellular Therapy, University Hospital Essen, Essen, Germany.
Source: Transplantation and cellular therapy [Transplant Cell Ther] 2026 Apr; Vol. 32 (4), pp. 434.e1-434.e11. Date of Electronic Publication: 2025 Dec 13.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101774629 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-6367 (Electronic) Linking ISSN: 26666367 NLM ISO Abbreviation: Transplant Cell Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Higher HLA-DRB1 Evolutionary Divergence Is Associated with Reduced Relapse and Improved Survival after Matched Unrelated Hematopoietic Cell Transplantation.
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  Data: <searchLink fieldCode="AU" term="%22Saultz+JN%22">Saultz JN</searchLink>; Division of Hematology/Oncology, Oregon Health & Sciences University Portland, Oregon. Electronic address: saultzje@ohsu.edu.<br /><searchLink fieldCode="AU" term="%22Bolon+YT%22">Bolon YT</searchLink>; Center for International Blood and Marrow Transplant Research, NMDP, Minneapolis, Minnesota.<br /><searchLink fieldCode="AU" term="%22Wang+T%22">Wang T</searchLink>; Division of Biostatistics, Data Science Institute, Medical College of Wisconsin, Milwaukee, Wisconsin; Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Spellman+SR%22">Spellman SR</searchLink>; Center for International Blood and Marrow Transplant Research, NMDP, Minneapolis, Minnesota.<br /><searchLink fieldCode="AU" term="%22Lee+SJ%22">Lee SJ</searchLink>; Fred Hutchinson Cancer Center, Seattle, Washington.<br /><searchLink fieldCode="AU" term="%22He+M%22">He M</searchLink>; Center for International Blood and Marrow Transplant Research, NMDP, Minneapolis, Minnesota.<br /><searchLink fieldCode="AU" term="%22Camacho-Bydume+C%22">Camacho-Bydume C</searchLink>; Hackensack University Medical Center, Hackensack, New Jersey.<br /><searchLink fieldCode="AU" term="%22Krishna+C%22">Krishna C</searchLink>; Broad Institute of MIT, Harvard Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Chowell+D%22">Chowell D</searchLink>; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Shaffer+BC%22">Shaffer BC</searchLink>; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York; Weill Cornell Medical College, New York, New York.<br /><searchLink fieldCode="AU" term="%22Hsu+KC%22">Hsu KC</searchLink>; Weill Cornell Medical College, New York, New York; Immunology Program, Sloan Kettering Institute for Cancer Research, New York, New York.<br /><searchLink fieldCode="AU" term="%22Paczesny+S%22">Paczesny S</searchLink>; Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina.<br /><searchLink fieldCode="AU" term="%22Gadalla+SM%22">Gadalla SM</searchLink>; Division of Cancer Epidemiology and Genetics, National Institutes of Health, National Cancer Institute, Clinical Genetics Branch, Rockville, Maryland.<br /><searchLink fieldCode="AU" term="%22Marsh+SGE%22">Marsh SGE</searchLink>; University College London Cancer Institute, Royal Free Campus, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Betts+BC%22">Betts BC</searchLink>; Roswell Park Cancer Institute, Buffalo, New York.<br /><searchLink fieldCode="AU" term="%22Arrieta-Bolaños+E%22">Arrieta-Bolaños E</searchLink>; Institute for Experimental Cellular Therapy, University Hospital Essen, Essen, Germany.
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