Comparative Analysis of Artificial Intelligence-Based Quantification versus Visual Rating of Enlarged Perivascular Spaces in the Multi-Ethnic Study of Atherosclerosis Cohort.

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Title: Comparative Analysis of Artificial Intelligence-Based Quantification versus Visual Rating of Enlarged Perivascular Spaces in the Multi-Ethnic Study of Atherosclerosis Cohort.
Authors: Torres MF; From the Neuroimage Analytics Laboratory (NAL), Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), University of Texas Health Science Center at San Antonio, San Antonio, Texas., Charisis S; From the Neuroimage Analytics Laboratory (NAL), Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), University of Texas Health Science Center at San Antonio, San Antonio, Texas.; Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, Texas., Rashid T; From the Neuroimage Analytics Laboratory (NAL), Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), University of Texas Health Science Center at San Antonio, San Antonio, Texas., Brandigampala SR; From the Neuroimage Analytics Laboratory (NAL), Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), University of Texas Health Science Center at San Antonio, San Antonio, Texas., Hiatt KD; Department of Radiology (K.D.H., C.T.W.), Wake Forest School of Medicine, Winston-Salem, North Carolina., Ware JB; Department of Radiology (J.B.W., I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Whitlow CT; Department of Radiology (K.D.H., C.T.W.), Wake Forest School of Medicine, Winston-Salem, North Carolina., Nasrallah IM; Department of Radiology (J.B.W., I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.; Center of Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Romero JR; Department of Neurology (J.R.R.), Boston University School of Medicine, Boston, Massachusetts., Tanley JE; Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, North Carolina., Seshadri S; From the Neuroimage Analytics Laboratory (NAL), Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), University of Texas Health Science Center at San Antonio, San Antonio, Texas.; Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, Texas., Hohman TJ; Vanderbilt Memory and Alzheimer's Center (T.J.H.), Vanderbilt University Medical Center, Nashville, Tennessee., Heckbert SR; Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of Washington, Seattle, Washington., Davatzikos C; Department of Radiology (J.B.W., I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.; Center of Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Hughes TM; Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, North Carolina., Habes M; From the Neuroimage Analytics Laboratory (NAL), Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), University of Texas Health Science Center at San Antonio, San Antonio, Texas habes@uthscsa.edu.
Source: AJNR. American journal of neuroradiology [AJNR Am J Neuroradiol] 2026 May 04; Vol. 47 (5), pp. 1259-1265. Date of Electronic Publication: 2026 May 04.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: American Society of Neuroradiology Country of Publication: United States NLM ID: 8003708 Publication Model: Electronic Cited Medium: Internet ISSN: 1936-959X (Electronic) Linking ISSN: 01956108 NLM ISO Abbreviation: AJNR Am J Neuroradiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Comparative Analysis of Artificial Intelligence-Based Quantification versus Visual Rating of Enlarged Perivascular Spaces in the Multi-Ethnic Study of Atherosclerosis Cohort.
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  Data: <searchLink fieldCode="AU" term="%22Torres+MF%22">Torres MF</searchLink>; From the Neuroimage Analytics Laboratory (NAL), Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), University of Texas Health Science Center at San Antonio, San Antonio, Texas.<br /><searchLink fieldCode="AU" term="%22Charisis+S%22">Charisis S</searchLink>; From the Neuroimage Analytics Laboratory (NAL), Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), University of Texas Health Science Center at San Antonio, San Antonio, Texas.; Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, Texas.<br /><searchLink fieldCode="AU" term="%22Rashid+T%22">Rashid T</searchLink>; From the Neuroimage Analytics Laboratory (NAL), Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), University of Texas Health Science Center at San Antonio, San Antonio, Texas.<br /><searchLink fieldCode="AU" term="%22Brandigampala+SR%22">Brandigampala SR</searchLink>; From the Neuroimage Analytics Laboratory (NAL), Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), University of Texas Health Science Center at San Antonio, San Antonio, Texas.<br /><searchLink fieldCode="AU" term="%22Hiatt+KD%22">Hiatt KD</searchLink>; Department of Radiology (K.D.H., C.T.W.), Wake Forest School of Medicine, Winston-Salem, North Carolina.<br /><searchLink fieldCode="AU" term="%22Ware+JB%22">Ware JB</searchLink>; Department of Radiology (J.B.W., I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Whitlow+CT%22">Whitlow CT</searchLink>; Department of Radiology (K.D.H., C.T.W.), Wake Forest School of Medicine, Winston-Salem, North Carolina.<br /><searchLink fieldCode="AU" term="%22Nasrallah+IM%22">Nasrallah IM</searchLink>; Department of Radiology (J.B.W., I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.; Center of Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Romero+JR%22">Romero JR</searchLink>; Department of Neurology (J.R.R.), Boston University School of Medicine, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Tanley+JE%22">Tanley JE</searchLink>; Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, North Carolina.<br /><searchLink fieldCode="AU" term="%22Seshadri+S%22">Seshadri S</searchLink>; From the Neuroimage Analytics Laboratory (NAL), Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), University of Texas Health Science Center at San Antonio, San Antonio, Texas.; Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, Texas.<br /><searchLink fieldCode="AU" term="%22Hohman+TJ%22">Hohman TJ</searchLink>; Vanderbilt Memory and Alzheimer's Center (T.J.H.), Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Heckbert+SR%22">Heckbert SR</searchLink>; Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of Washington, Seattle, Washington.<br /><searchLink fieldCode="AU" term="%22Davatzikos+C%22">Davatzikos C</searchLink>; Department of Radiology (J.B.W., I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.; Center of Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Hughes+TM%22">Hughes TM</searchLink>; Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, North Carolina.<br /><searchLink fieldCode="AU" term="%22Habes+M%22">Habes M</searchLink>; From the Neuroimage Analytics Laboratory (NAL), Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), University of Texas Health Science Center at San Antonio, San Antonio, Texas habes@uthscsa.edu.
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