View in EDS HTML Full Text PDF Full Text

Complete structures of the YenTc holotoxin prepore and pore reveal the evolutionary basis for chitinase incorporation into ABC toxins.

Saved in:
Bibliographic Details
Title: Complete structures of the YenTc holotoxin prepore and pore reveal the evolutionary basis for chitinase incorporation into ABC toxins.
Authors: Low YS; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia., Roche SG; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia., Aleksandrova NA; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia., Foley G; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia., Low JK; School of Life and Environmental Sciences, University of Sydney, Camperdown, NSW, Australia., Box JK; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia., Croll TI; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.; Altos Labs, Cambridge, UK., Chassagnon IR; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.; Servatus Biopharmaceuticals, Coolum Beach, QLD, Australia., Lott JS; School of Biological Sciences, University of Auckland, Auckland, New Zealand., Deplazes E; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia., Bodén M; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia., Hurst MR; Bioeconomy Science Institute, AgResearch, Lincoln Research Centre, Christchurch, New Zealand., Piper SJ; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia. sarah.piper@monash.edu.au.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia. sarah.piper@monash.edu.au.; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia. sarah.piper@monash.edu.au.; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, Australia. sarah.piper@monash.edu.au., Landsberg MJ; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia. m.landsberg@uq.edu.au.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia. m.landsberg@uq.edu.au.; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, Australia. m.landsberg@uq.edu.au.
Source: Nature communications [Nat Commun] 2025 Dec 15; Vol. 16 (1), pp. 11121. Date of Electronic Publication: 2025 Dec 15.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41397958
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Complete structures of the YenTc holotoxin prepore and pore reveal the evolutionary basis for chitinase incorporation into ABC toxins.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Low+YS%22">Low YS</searchLink>; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Roche+SG%22">Roche SG</searchLink>; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Aleksandrova+NA%22">Aleksandrova NA</searchLink>; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Foley+G%22">Foley G</searchLink>; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Low+JK%22">Low JK</searchLink>; School of Life and Environmental Sciences, University of Sydney, Camperdown, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Box+JK%22">Box JK</searchLink>; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Croll+TI%22">Croll TI</searchLink>; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.; Altos Labs, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Chassagnon+IR%22">Chassagnon IR</searchLink>; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.; Servatus Biopharmaceuticals, Coolum Beach, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Lott+JS%22">Lott JS</searchLink>; School of Biological Sciences, University of Auckland, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Deplazes+E%22">Deplazes E</searchLink>; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Bodén+M%22">Bodén M</searchLink>; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Hurst+MR%22">Hurst MR</searchLink>; Bioeconomy Science Institute, AgResearch, Lincoln Research Centre, Christchurch, New Zealand.<br /><searchLink fieldCode="AU" term="%22Piper+SJ%22">Piper SJ</searchLink>; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia. sarah.piper@monash.edu.au.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia. sarah.piper@monash.edu.au.; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia. sarah.piper@monash.edu.au.; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, Australia. sarah.piper@monash.edu.au.<br /><searchLink fieldCode="AU" term="%22Landsberg+MJ%22">Landsberg MJ</searchLink>; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia. m.landsberg@uq.edu.au.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia. m.landsberg@uq.edu.au.; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, Australia. m.landsberg@uq.edu.au.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Dec 15; Vol. 16 (1), pp. 11121. <i>Date of Electronic Publication: </i>2025 Dec 15.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41397958
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41467-025-66050-x
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 11121
    Titles:
      – TitleFull: Complete structures of the YenTc holotoxin prepore and pore reveal the evolutionary basis for chitinase incorporation into ABC toxins.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Low YS
      – PersonEntity:
          Name:
            NameFull: Roche SG
      – PersonEntity:
          Name:
            NameFull: Aleksandrova NA
      – PersonEntity:
          Name:
            NameFull: Foley G
      – PersonEntity:
          Name:
            NameFull: Low JK
      – PersonEntity:
          Name:
            NameFull: Box JK
      – PersonEntity:
          Name:
            NameFull: Croll TI
      – PersonEntity:
          Name:
            NameFull: Chassagnon IR
      – PersonEntity:
          Name:
            NameFull: Lott JS
      – PersonEntity:
          Name:
            NameFull: Deplazes E
      – PersonEntity:
          Name:
            NameFull: Bodén M
      – PersonEntity:
          Name:
            NameFull: Hurst MR
      – PersonEntity:
          Name:
            NameFull: Piper SJ
      – PersonEntity:
          Name:
            NameFull: Landsberg MJ
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 15
              M: 12
              Text: 2025 Dec 15
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
          Numbering:
            – Type: volume
              Value: 16
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature communications
              Type: main
ResultId 1