View in EDS HTML Full Text PDF Full Text

Mitochondrial RNA cytosolic leakage drives the SASP.

Saved in:
Bibliographic Details
Title: Mitochondrial RNA cytosolic leakage drives the SASP.
Authors: Victorelli S; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA. Victorelli.Stella@mayo.edu.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA. Victorelli.Stella@mayo.edu., Eppard M; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Martini H; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Woo SH; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Everts SPA; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Lee G; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Pirius N; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Han N; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.; Molecular Pharmacology and Experimental Therapeutics Graduate Program, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN, USA., Liang EY; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.; Mayo Clinic Medical Scientist Training Program, Mayo Clinic, Rochester, MN, USA., Franco AC; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Han Y; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Saul D; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.; Robert Bosch Center for Tumor Diseases, Stuttgart, Germany., Nóvoa E; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.; CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Santiago de Compostela, Spain., Nogueiras R; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.; CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Santiago de Compostela, Spain.; Galicia Agency of Innovation (GAIN), Xunta de Galicia, Santiago de Compostela, Spain., Splinter PL; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., O'Hara SP; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Morgenthaler O; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Valenzuela-Pérez L; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Kim Lee HS; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Jurk D; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., LaRusso NF; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Hirsova P; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Passos JF; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA. passos.joao@mayo.edu.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA. passos.joao@mayo.edu.
Source: Nature communications [Nat Commun] 2025 Dec 15; Vol. 16 (1), pp. 10992. Date of Electronic Publication: 2025 Dec 15.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41398033
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Mitochondrial RNA cytosolic leakage drives the SASP.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Victorelli+S%22">Victorelli S</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA. Victorelli.Stella@mayo.edu.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA. Victorelli.Stella@mayo.edu.<br /><searchLink fieldCode="AU" term="%22Eppard+M%22">Eppard M</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Martini+H%22">Martini H</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Woo+SH%22">Woo SH</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Everts+SPA%22">Everts SPA</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Lee+G%22">Lee G</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Pirius+N%22">Pirius N</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Han+N%22">Han N</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.; Molecular Pharmacology and Experimental Therapeutics Graduate Program, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Liang+EY%22">Liang EY</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.; Mayo Clinic Medical Scientist Training Program, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Franco+AC%22">Franco AC</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Han+Y%22">Han Y</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Saul+D%22">Saul D</searchLink>; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.; Robert Bosch Center for Tumor Diseases, Stuttgart, Germany.<br /><searchLink fieldCode="AU" term="%22Nóvoa+E%22">Nóvoa E</searchLink>; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.; CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22Nogueiras+R%22">Nogueiras R</searchLink>; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.; CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Santiago de Compostela, Spain.; Galicia Agency of Innovation (GAIN), Xunta de Galicia, Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22Splinter+PL%22">Splinter PL</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22O'Hara+SP%22">O'Hara SP</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Morgenthaler+O%22">Morgenthaler O</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Valenzuela-Pérez+L%22">Valenzuela-Pérez L</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Kim+Lee+HS%22">Kim Lee HS</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Jurk+D%22">Jurk D</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22LaRusso+NF%22">LaRusso NF</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Hirsova+P%22">Hirsova P</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Passos+JF%22">Passos JF</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA. passos.joao@mayo.edu.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA. passos.joao@mayo.edu.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Dec 15; Vol. 16 (1), pp. 10992. <i>Date of Electronic Publication: </i>2025 Dec 15.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41398033
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41467-025-66159-z
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 10992
    Titles:
      – TitleFull: Mitochondrial RNA cytosolic leakage drives the SASP.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Victorelli S
      – PersonEntity:
          Name:
            NameFull: Eppard M
      – PersonEntity:
          Name:
            NameFull: Martini H
      – PersonEntity:
          Name:
            NameFull: Woo SH
      – PersonEntity:
          Name:
            NameFull: Everts SPA
      – PersonEntity:
          Name:
            NameFull: Lee G
      – PersonEntity:
          Name:
            NameFull: Pirius N
      – PersonEntity:
          Name:
            NameFull: Han N
      – PersonEntity:
          Name:
            NameFull: Liang EY
      – PersonEntity:
          Name:
            NameFull: Franco AC
      – PersonEntity:
          Name:
            NameFull: Han Y
      – PersonEntity:
          Name:
            NameFull: Saul D
      – PersonEntity:
          Name:
            NameFull: Nóvoa E
      – PersonEntity:
          Name:
            NameFull: Nogueiras R
      – PersonEntity:
          Name:
            NameFull: Splinter PL
      – PersonEntity:
          Name:
            NameFull: O'Hara SP
      – PersonEntity:
          Name:
            NameFull: Morgenthaler O
      – PersonEntity:
          Name:
            NameFull: Valenzuela-Pérez L
      – PersonEntity:
          Name:
            NameFull: Kim Lee HS
      – PersonEntity:
          Name:
            NameFull: Jurk D
      – PersonEntity:
          Name:
            NameFull: LaRusso NF
      – PersonEntity:
          Name:
            NameFull: Hirsova P
      – PersonEntity:
          Name:
            NameFull: Passos JF
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 15
              M: 12
              Text: 2025 Dec 15
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
          Numbering:
            – Type: volume
              Value: 16
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature communications
              Type: main
ResultId 1