Diagnosis and Management of Food Protein-Induced Allergic Proctocolitis in the pediatric age: A position paper from the Italian Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the Italian Society for Pediatric Allergy and Immunology.

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Title: Diagnosis and Management of Food Protein-Induced Allergic Proctocolitis in the pediatric age: A position paper from the Italian Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the Italian Society for Pediatric Allergy and Immunology.
Authors: Coppola S; Pediatric Allergy Program at the Department of Translational Medical Science, University of Naples 'Federico II', Naples, Italy.; NutriTechLab at CEINGE Advanced Biotechnologies, University of Naples 'Federico II', Naples, Italy.; European Laboratory for the Investigation of Food-Induced Diseases, University of Naples 'Federico II', Naples, Italy.; Task Force for Microbiome Studies, University of Naples 'Federico II', Naples, Italy., Carucci L; Pediatric Allergy Program at the Department of Translational Medical Science, University of Naples 'Federico II', Naples, Italy.; NutriTechLab at CEINGE Advanced Biotechnologies, University of Naples 'Federico II', Naples, Italy.; European Laboratory for the Investigation of Food-Induced Diseases, University of Naples 'Federico II', Naples, Italy.; Task Force for Microbiome Studies, University of Naples 'Federico II', Naples, Italy., Anania C; Department of Maternal, Infantile and Urological Science, Sapienza University of Rome, Rome, Italy., Auricchio R; Pediatric Allergy Program at the Department of Translational Medical Science, University of Naples 'Federico II', Naples, Italy.; European Laboratory for the Investigation of Food-Induced Diseases, University of Naples 'Federico II', Naples, Italy., Baldassarre M; Department of Interdisciplinary Medicine, Neonatology and NICU Section, University of Bari, Bari, Italy., Calvani M; Operative Unit of Pediatrics, S. Camillo-Forlanini Hospital, Rome, Italy., Cecere G; Pediatric Allergy Program at the Department of Translational Medical Science, University of Naples 'Federico II', Naples, Italy., D'Auria E; Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy.; Allergy Unit-Department of Pediatrics, Buzzi Children's Hospital, Milan, Italy., Decimo F; Department of Woman, Child and of General and Specialized Surgery, University of Campania Luigi, Vanvitelli, Naples, Italy., Malamisura M; Gastroenterology and Nutrition Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy., Arasi S; Allergy Unit - Area of Translational Research in Pediatric Specialties, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy., Borrelli O; Division of Neurogastroenterology and Motility, Department of Pediatric Gastroenterology, University College London (UCL) Institute of Child Health and Great Ormond Street Hospital, London, UK., Brunese FP; Primary Care Pediatrics, ASL Caserta, Caserta, Italy., Cuomo B; Central Operative Unit of Pediatrics and Allergy Center for Children and Adults, Santa Rosa Hospital, Viterbo, Italy., Giorgio V; UOSD Spina Bifida e Altre Branche Specialistiche, Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario 'A. Gemelli' IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy., Indolfi C; Department of Woman, Child and of General and Specialized Surgery, University of Campania Luigi, Vanvitelli, Naples, Italy., Martinelli M; Pediatric Allergy Program at the Department of Translational Medical Science, University of Naples 'Federico II', Naples, Italy., Pensabene L; Pediatric Unit, Department of Medical and Surgical Sciences, University 'Magna Graecia' of Catanzaro, Catanzaro, Italy., Salvatore S; Department of Pediatrics Department of Medicine and Technical Innovation, 'F. Del Ponte' Hospital, University of Insubria, Varese, Italy., Tambucci R; Gastroenterology and Nutrition Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy., Klain A; Department of Woman, Child and of General and Specialized Surgery, University of Campania Luigi, Vanvitelli, Naples, Italy., Marasco G; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Miraglia Del Giudice M; Department of Woman, Child and of General and Specialized Surgery, University of Campania Luigi, Vanvitelli, Naples, Italy., Romano C; Pediatric Gastroenterology and Cystic Fibrosis Unit, Department of Human Pathology in Adulthood and Childhood 'G. Barresi', University of Messina, Messina, Italy., Berni Canani R; Pediatric Allergy Program at the Department of Translational Medical Science, University of Naples 'Federico II', Naples, Italy.; NutriTechLab at CEINGE Advanced Biotechnologies, University of Naples 'Federico II', Naples, Italy.; European Laboratory for the Investigation of Food-Induced Diseases, University of Naples 'Federico II', Naples, Italy.; Task Force for Microbiome Studies, University of Naples 'Federico II', Naples, Italy.
Source: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology [Pediatr Allergy Immunol] 2025 Dec; Vol. 36 (12), pp. e70264.
Publication Type: Journal Article; Practice Guideline
Journal Info: Publisher: Blackwell Publishing Country of Publication: England NLM ID: 9106718 Publication Model: Print Cited Medium: Internet ISSN: 1399-3038 (Electronic) Linking ISSN: 09056157 NLM ISO Abbreviation: Pediatr Allergy Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Diagnosis and Management of Food Protein-Induced Allergic Proctocolitis in the pediatric age: A position paper from the Italian Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the Italian Society for Pediatric Allergy and Immunology.
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  Data: <searchLink fieldCode="AU" term="%22Coppola+S%22">Coppola S</searchLink>; Pediatric Allergy Program at the Department of Translational Medical Science, University of Naples 'Federico II', Naples, Italy.; NutriTechLab at CEINGE Advanced Biotechnologies, University of Naples 'Federico II', Naples, Italy.; European Laboratory for the Investigation of Food-Induced Diseases, University of Naples 'Federico II', Naples, Italy.; Task Force for Microbiome Studies, University of Naples 'Federico II', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Carucci+L%22">Carucci L</searchLink>; Pediatric Allergy Program at the Department of Translational Medical Science, University of Naples 'Federico II', Naples, Italy.; NutriTechLab at CEINGE Advanced Biotechnologies, University of Naples 'Federico II', Naples, Italy.; European Laboratory for the Investigation of Food-Induced Diseases, University of Naples 'Federico II', Naples, Italy.; Task Force for Microbiome Studies, University of Naples 'Federico II', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Anania+C%22">Anania C</searchLink>; Department of Maternal, Infantile and Urological Science, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Auricchio+R%22">Auricchio R</searchLink>; Pediatric Allergy Program at the Department of Translational Medical Science, University of Naples 'Federico II', Naples, Italy.; European Laboratory for the Investigation of Food-Induced Diseases, University of Naples 'Federico II', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Baldassarre+M%22">Baldassarre M</searchLink>; Department of Interdisciplinary Medicine, Neonatology and NICU Section, University of Bari, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Calvani+M%22">Calvani M</searchLink>; Operative Unit of Pediatrics, S. Camillo-Forlanini Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Cecere+G%22">Cecere G</searchLink>; Pediatric Allergy Program at the Department of Translational Medical Science, University of Naples 'Federico II', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22D'Auria+E%22">D'Auria E</searchLink>; Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy.; Allergy Unit-Department of Pediatrics, Buzzi Children's Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Decimo+F%22">Decimo F</searchLink>; Department of Woman, Child and of General and Specialized Surgery, University of Campania Luigi, Vanvitelli, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Malamisura+M%22">Malamisura M</searchLink>; Gastroenterology and Nutrition Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Arasi+S%22">Arasi S</searchLink>; Allergy Unit - Area of Translational Research in Pediatric Specialties, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Borrelli+O%22">Borrelli O</searchLink>; Division of Neurogastroenterology and Motility, Department of Pediatric Gastroenterology, University College London (UCL) Institute of Child Health and Great Ormond Street Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Brunese+FP%22">Brunese FP</searchLink>; Primary Care Pediatrics, ASL Caserta, Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Cuomo+B%22">Cuomo B</searchLink>; Central Operative Unit of Pediatrics and Allergy Center for Children and Adults, Santa Rosa Hospital, Viterbo, Italy.<br /><searchLink fieldCode="AU" term="%22Giorgio+V%22">Giorgio V</searchLink>; UOSD Spina Bifida e Altre Branche Specialistiche, Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario 'A. Gemelli' IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Indolfi+C%22">Indolfi C</searchLink>; Department of Woman, Child and of General and Specialized Surgery, University of Campania Luigi, Vanvitelli, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Martinelli+M%22">Martinelli M</searchLink>; Pediatric Allergy Program at the Department of Translational Medical Science, University of Naples 'Federico II', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Pensabene+L%22">Pensabene L</searchLink>; Pediatric Unit, Department of Medical and Surgical Sciences, University 'Magna Graecia' of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Salvatore+S%22">Salvatore S</searchLink>; Department of Pediatrics Department of Medicine and Technical Innovation, 'F. Del Ponte' Hospital, University of Insubria, Varese, Italy.<br /><searchLink fieldCode="AU" term="%22Tambucci+R%22">Tambucci R</searchLink>; Gastroenterology and Nutrition Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Klain+A%22">Klain A</searchLink>; Department of Woman, Child and of General and Specialized Surgery, University of Campania Luigi, Vanvitelli, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Marasco+G%22">Marasco G</searchLink>; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Miraglia+Del+Giudice+M%22">Miraglia Del Giudice M</searchLink>; Department of Woman, Child and of General and Specialized Surgery, University of Campania Luigi, Vanvitelli, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Romano+C%22">Romano C</searchLink>; Pediatric Gastroenterology and Cystic Fibrosis Unit, Department of Human Pathology in Adulthood and Childhood 'G. Barresi', University of Messina, Messina, Italy.<br /><searchLink fieldCode="AU" term="%22Berni+Canani+R%22">Berni Canani R</searchLink>; Pediatric Allergy Program at the Department of Translational Medical Science, University of Naples 'Federico II', Naples, Italy.; NutriTechLab at CEINGE Advanced Biotechnologies, University of Naples 'Federico II', Naples, Italy.; European Laboratory for the Investigation of Food-Induced Diseases, University of Naples 'Federico II', Naples, Italy.; Task Force for Microbiome Studies, University of Naples 'Federico II', Naples, Italy.
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