Detection of TDP-43 seeds in CSF of presymptomatic and symptomatic genetic FTD/ALS.

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Title: Detection of TDP-43 seeds in CSF of presymptomatic and symptomatic genetic FTD/ALS.
Authors: Dellarole IL; SSD Laboratory Medicine-Laboratory of Clinical Pathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Aprea V; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Catania M; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Battipaglia C; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Romeo A; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Villa C; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Burato A; Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore Di Studi Avanzati (SISSA), Trieste, Italy., Celauro L; Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore Di Studi Avanzati (SISSA), Trieste, Italy., Bella ED; Neurology 3 - Neuroalgology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Riva N; Neurology 3 - Neuroalgology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Salvi E; Data Science Center and Computational multi-Omics of Neurological Disorders (MIND) Lab, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Rossi G; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Fede GD; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Legname G; Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore Di Studi Avanzati (SISSA), Trieste, Italy., De Houwer JFH; Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre (Erasmus MC), Rotterdam, The Netherlands., Alberici A; Department of Continuity of Care and Frailty, ASST Spedali Civili Brescia Hospital, Brescia, Italy., Borroni B; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy., Seelaar H; Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre (Erasmus MC), Rotterdam, The Netherlands., van Swieten JC; Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre (Erasmus MC), Rotterdam, The Netherlands., Moda F; SSD Laboratory Medicine-Laboratory of Clinical Pathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy., Caroppo P; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Dec; Vol. 21 (12), pp. e70989.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1552-5279
DOI:10.1002/alz.70989