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Detection of TDP-43 seeds in CSF of presymptomatic and symptomatic genetic FTD/ALS.

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Title: Detection of TDP-43 seeds in CSF of presymptomatic and symptomatic genetic FTD/ALS.
Authors: Dellarole IL; SSD Laboratory Medicine-Laboratory of Clinical Pathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Aprea V; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Catania M; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Battipaglia C; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Romeo A; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Villa C; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Burato A; Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore Di Studi Avanzati (SISSA), Trieste, Italy., Celauro L; Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore Di Studi Avanzati (SISSA), Trieste, Italy., Bella ED; Neurology 3 - Neuroalgology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Riva N; Neurology 3 - Neuroalgology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Salvi E; Data Science Center and Computational multi-Omics of Neurological Disorders (MIND) Lab, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Rossi G; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Fede GD; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Legname G; Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore Di Studi Avanzati (SISSA), Trieste, Italy., De Houwer JFH; Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre (Erasmus MC), Rotterdam, The Netherlands., Alberici A; Department of Continuity of Care and Frailty, ASST Spedali Civili Brescia Hospital, Brescia, Italy., Borroni B; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy., Seelaar H; Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre (Erasmus MC), Rotterdam, The Netherlands., van Swieten JC; Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre (Erasmus MC), Rotterdam, The Netherlands., Moda F; SSD Laboratory Medicine-Laboratory of Clinical Pathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy., Caroppo P; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Dec; Vol. 21 (12), pp. e70989.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Detection of TDP-43 seeds in CSF of presymptomatic and symptomatic genetic FTD/ALS.
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  Data: <searchLink fieldCode="AU" term="%22Dellarole+IL%22">Dellarole IL</searchLink>; SSD Laboratory Medicine-Laboratory of Clinical Pathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Aprea+V%22">Aprea V</searchLink>; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Catania+M%22">Catania M</searchLink>; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Battipaglia+C%22">Battipaglia C</searchLink>; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Romeo+A%22">Romeo A</searchLink>; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Villa+C%22">Villa C</searchLink>; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Burato+A%22">Burato A</searchLink>; Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore Di Studi Avanzati (SISSA), Trieste, Italy.<br /><searchLink fieldCode="AU" term="%22Celauro+L%22">Celauro L</searchLink>; Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore Di Studi Avanzati (SISSA), Trieste, Italy.<br /><searchLink fieldCode="AU" term="%22Bella+ED%22">Bella ED</searchLink>; Neurology 3 - Neuroalgology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Riva+N%22">Riva N</searchLink>; Neurology 3 - Neuroalgology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Salvi+E%22">Salvi E</searchLink>; Data Science Center and Computational multi-Omics of Neurological Disorders (MIND) Lab, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Rossi+G%22">Rossi G</searchLink>; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Fede+GD%22">Fede GD</searchLink>; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Legname+G%22">Legname G</searchLink>; Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore Di Studi Avanzati (SISSA), Trieste, Italy.<br /><searchLink fieldCode="AU" term="%22De+Houwer+JFH%22">De Houwer JFH</searchLink>; Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre (Erasmus MC), Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Alberici+A%22">Alberici A</searchLink>; Department of Continuity of Care and Frailty, ASST Spedali Civili Brescia Hospital, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Borroni+B%22">Borroni B</searchLink>; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Seelaar+H%22">Seelaar H</searchLink>; Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre (Erasmus MC), Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Swieten+JC%22">van Swieten JC</searchLink>; Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre (Erasmus MC), Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Moda+F%22">Moda F</searchLink>; SSD Laboratory Medicine-Laboratory of Clinical Pathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Caroppo+P%22">Caroppo P</searchLink>; Neurology 8 - Dementias and degenerative diseases of CNS Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons%2C+Ltd%22">John Wiley & Sons, Ltd </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101231978 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1552-5279 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215525260%22">15525260 </searchLink><i>NLM ISO Abbreviation: </i>Alzheimers Dement <i>Subsets: </i>MEDLINE
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