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Anti-inflammatory activity of α-tomatine via inhibition of the MAPK and NF-κB signaling pathway in vitro and ex vivo.

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Title: Anti-inflammatory activity of α-tomatine via inhibition of the MAPK and NF-κB signaling pathway in vitro and ex vivo.
Authors: Chen CW; Department of Physical Education, Health, and Recreation, Teachers College, National Chiayi University, Chiayi, Taiwan, ROC., Hsieh CC; Institutes of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Hsieh YT; Institutes of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC., Lin MJ; Department of Physical Education, Health, and Recreation, Teachers College, National Chiayi University, Chiayi, Taiwan, ROC., Chiu PH; Department of Educational Management, National Taipei University of Education, Taipei, Taiwan, ROC., Juan CC; Institutes of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC.; Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC., Lieu FK; Department of Physical Medicine and Rehabilitation, Cheng Hsin General Hospital, Taipei, Taiwan, ROC., Wang SW; Department of Physiology and Pharmacology, College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC., Wang PS; Institutes of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC.; Medical Center of Aging Research, China Medical University Hospital, Taichung, Taiwan, ROC.
Source: International journal of medical sciences [Int J Med Sci] 2026 Jan 01; Vol. 23 (1), pp. 194-203. Date of Electronic Publication: 2026 Jan 01 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101213954 Publication Model: eCollection Cited Medium: Internet ISSN: 1449-1907 (Electronic) Linking ISSN: 14491907 NLM ISO Abbreviation: Int J Med Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Chen+CW%22">Chen CW</searchLink>; Department of Physical Education, Health, and Recreation, Teachers College, National Chiayi University, Chiayi, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Hsieh+CC%22">Hsieh CC</searchLink>; Institutes of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Hsieh+YT%22">Hsieh YT</searchLink>; Institutes of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Lin+MJ%22">Lin MJ</searchLink>; Department of Physical Education, Health, and Recreation, Teachers College, National Chiayi University, Chiayi, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Chiu+PH%22">Chiu PH</searchLink>; Department of Educational Management, National Taipei University of Education, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Juan+CC%22">Juan CC</searchLink>; Institutes of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC.; Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Lieu+FK%22">Lieu FK</searchLink>; Department of Physical Medicine and Rehabilitation, Cheng Hsin General Hospital, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Wang+SW%22">Wang SW</searchLink>; Department of Physiology and Pharmacology, College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Wang+PS%22">Wang PS</searchLink>; Institutes of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC.; Medical Center of Aging Research, China Medical University Hospital, Taichung, Taiwan, ROC.
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        Value: 10.7150/ijms.118250
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              Text: 2026 Jan 01
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