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Transforming Amino Acids into Serotonin 5-HT2A Receptor Ligands Using Photochemistry.

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Title: Transforming Amino Acids into Serotonin 5-HT2A Receptor Ligands Using Photochemistry.
Authors: Beckett JOS; Department of Chemistry, University of California, Davis, California 95616, United States.; Institute for Psychedelics and Neurotherapeutics, University of California, Davis, California 95616, United States., Buzdygon R; HepatoChem Inc., 100 Cummings Center, Suite 360B Beverly, Massachusetts 01915, United States., Nguyen S; HepatoChem Inc., 100 Cummings Center, Suite 360B Beverly, Massachusetts 01915, United States., Clark AA; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States., Schalk SS; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States., Svanholm LEH; Department of Chemistry, University of California, Davis, California 95616, United States., Brasher TJ; Department of Chemistry, University of California, Davis, California 95616, United States.; Pharmacology and Toxicology Graduate Group, University of California, Davis, California 95616, United States.; Institute for Psychedelics and Neurotherapeutics, University of California, Davis, California 95616, United States., Bazin M; HepatoChem Inc., 100 Cummings Center, Suite 360B Beverly, Massachusetts 01915, United States., Cuccurazzu B; Department of Psychiatry, University of California San Diego, La Jolla, California 92093, United States., Halberstadt AL; Department of Psychiatry, University of California San Diego, La Jolla, California 92093, United States., McCorvy JD; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.; Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.; Cancer Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States., Mascal M; Department of Chemistry, University of California, Davis, California 95616, United States.; Pharmacology and Toxicology Graduate Group, University of California, Davis, California 95616, United States.
Source: Journal of the American Chemical Society [J Am Chem Soc] 2025 Dec 31; Vol. 147 (52), pp. 48400-48415. Date of Electronic Publication: 2025 Dec 16.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE
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  Data: Transforming Amino Acids into Serotonin 5-HT<subscript>2A</subscript> Receptor Ligands Using Photochemistry.
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  Data: <searchLink fieldCode="AU" term="%22Beckett+JOS%22">Beckett JOS</searchLink>; Department of Chemistry, University of California, Davis, California 95616, United States.; Institute for Psychedelics and Neurotherapeutics, University of California, Davis, California 95616, United States.<br /><searchLink fieldCode="AU" term="%22Buzdygon+R%22">Buzdygon R</searchLink>; HepatoChem Inc., 100 Cummings Center, Suite 360B Beverly, Massachusetts 01915, United States.<br /><searchLink fieldCode="AU" term="%22Nguyen+S%22">Nguyen S</searchLink>; HepatoChem Inc., 100 Cummings Center, Suite 360B Beverly, Massachusetts 01915, United States.<br /><searchLink fieldCode="AU" term="%22Clark+AA%22">Clark AA</searchLink>; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.<br /><searchLink fieldCode="AU" term="%22Schalk+SS%22">Schalk SS</searchLink>; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.<br /><searchLink fieldCode="AU" term="%22Svanholm+LEH%22">Svanholm LEH</searchLink>; Department of Chemistry, University of California, Davis, California 95616, United States.<br /><searchLink fieldCode="AU" term="%22Brasher+TJ%22">Brasher TJ</searchLink>; Department of Chemistry, University of California, Davis, California 95616, United States.; Pharmacology and Toxicology Graduate Group, University of California, Davis, California 95616, United States.; Institute for Psychedelics and Neurotherapeutics, University of California, Davis, California 95616, United States.<br /><searchLink fieldCode="AU" term="%22Bazin+M%22">Bazin M</searchLink>; HepatoChem Inc., 100 Cummings Center, Suite 360B Beverly, Massachusetts 01915, United States.<br /><searchLink fieldCode="AU" term="%22Cuccurazzu+B%22">Cuccurazzu B</searchLink>; Department of Psychiatry, University of California San Diego, La Jolla, California 92093, United States.<br /><searchLink fieldCode="AU" term="%22Halberstadt+AL%22">Halberstadt AL</searchLink>; Department of Psychiatry, University of California San Diego, La Jolla, California 92093, United States.<br /><searchLink fieldCode="AU" term="%22McCorvy+JD%22">McCorvy JD</searchLink>; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.; Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.; Cancer Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.<br /><searchLink fieldCode="AU" term="%22Mascal+M%22">Mascal M</searchLink>; Department of Chemistry, University of California, Davis, California 95616, United States.; Pharmacology and Toxicology Graduate Group, University of California, Davis, California 95616, United States.
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  Data: <searchLink fieldCode="JN" term="%227503056%22">Journal of the American Chemical Society</searchLink> [J Am Chem Soc] 2025 Dec 31; Vol. 147 (52), pp. 48400-48415. <i>Date of Electronic Publication: </i>2025 Dec 16.
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              Text: 2025 Dec 31
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