Association between carotid-femoral pulse wave velocity and cardiovascular disease in individuals with moderate blood pressure: a systematic review and individual participant meta-analysis.

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Title: Association between carotid-femoral pulse wave velocity and cardiovascular disease in individuals with moderate blood pressure: a systematic review and individual participant meta-analysis.
Authors: Pavey H; Division of Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, Cambridge, UK hp409@cam.ac.uk.; Institute of Health Economics, Medical University of Innsbruck, Innsbruck, Austria.; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK., Wood A; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Cambridge Centre of Artifical Intelligence in Medicine, University of Cambridge, Cambridge, UK., Mceniery CM; Division of Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, Cambridge, UK., AlGhatrif M; Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.; Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA., Arshi B; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Brunner E; Institute of Epidemiology and Health Care, University College London, London, UK., Chen CH; School of Medicine, National Yang-Ming University, Taipei, Taiwan., Cheng HM; PhD Program of Interdisciplinary Medicine (PIM), National Yang Ming Chiao Tung University College of Medicine, Tapei, Taiwan.; Division of Faculty Development, Taipei Veterans General Hospital, Taipei, Taiwan.; Center for Evidence-based Medicine, Taipei Veterans General Hospital, Taipai, Taiwan., Hansen TW; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Steno Diabetes Center Copenhagen, Herlev, Capital Region of Denmark, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Ikram MK; Department of Epidemiology and Neurology, Erasmus MC, Rotterdam, The Netherlands., Kavousi M; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Kuh D; MRC Unit for Lifelong Health and Ageing at UCL, London, UK., Kuipers AL; Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Lakatta EG; Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA., Linneberg A; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Mattace Raso F; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Mitchell GF; Cardiovascular Engineering Inc, Norwood, Massachusetts, USA., Maldonado J; Clinica de Aveleira, Instituto de Investigação e Formação Cardiovascular, Coimbra, Portugal., Newman AB; Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Pereira T; Department of Tecnologia, Polytechnic University of Coimbra, Coimbra, Portugal., Maki-Petaja K; Division of Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, Cambridge, UK., Shipley M; Institute of Epidemiology and Health Care, University College London, London, UK., Vasan RS; Department of Medicine, Boston University, Boston, Massachusetts, USA.; University of Texas Health Science Center, San Antonio, Texas, USA.; NHLBI FHS, Framingham, Massachusetts, USA., Wong A; MRC Unit for Lifelong Health and Ageing at UCL, London, UK., Ben-Shlomo Y; Population Health Sciences, University of Bristol, Bristol, UK., Wilkinson IB; Division of Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, Cambridge, UK.; Cambridge Clinical Trials Unit, Cambridge, UK.
Source: BMJ open [BMJ Open] 2025 Dec 15; Vol. 15 (12), pp. e101368. Date of Electronic Publication: 2025 Dec 15.
Publication Type: Journal Article; Systematic Review; Meta-Analysis
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
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  Data: Association between carotid-femoral pulse wave velocity and cardiovascular disease in individuals with moderate blood pressure: a systematic review and individual participant meta-analysis.
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  Data: <searchLink fieldCode="AU" term="%22Pavey+H%22">Pavey H</searchLink>; Division of Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, Cambridge, UK hp409@cam.ac.uk.; Institute of Health Economics, Medical University of Innsbruck, Innsbruck, Austria.; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Wood+A%22">Wood A</searchLink>; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Cambridge Centre of Artifical Intelligence in Medicine, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Mceniery+CM%22">Mceniery CM</searchLink>; Division of Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22AlGhatrif+M%22">AlGhatrif M</searchLink>; Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.; Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Arshi+B%22">Arshi B</searchLink>; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Brunner+E%22">Brunner E</searchLink>; Institute of Epidemiology and Health Care, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Chen+CH%22">Chen CH</searchLink>; School of Medicine, National Yang-Ming University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Cheng+HM%22">Cheng HM</searchLink>; PhD Program of Interdisciplinary Medicine (PIM), National Yang Ming Chiao Tung University College of Medicine, Tapei, Taiwan.; Division of Faculty Development, Taipei Veterans General Hospital, Taipei, Taiwan.; Center for Evidence-based Medicine, Taipei Veterans General Hospital, Taipai, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hansen+TW%22">Hansen TW</searchLink>; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Steno Diabetes Center Copenhagen, Herlev, Capital Region of Denmark, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Ikram+MK%22">Ikram MK</searchLink>; Department of Epidemiology and Neurology, Erasmus MC, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kavousi+M%22">Kavousi M</searchLink>; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kuh+D%22">Kuh D</searchLink>; MRC Unit for Lifelong Health and Ageing at UCL, London, UK.<br /><searchLink fieldCode="AU" term="%22Kuipers+AL%22">Kuipers AL</searchLink>; Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Lakatta+EG%22">Lakatta EG</searchLink>; Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Linneberg+A%22">Linneberg A</searchLink>; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Mattace+Raso+F%22">Mattace Raso F</searchLink>; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Mitchell+GF%22">Mitchell GF</searchLink>; Cardiovascular Engineering Inc, Norwood, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Maldonado+J%22">Maldonado J</searchLink>; Clinica de Aveleira, Instituto de Investigação e Formação Cardiovascular, Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Newman+AB%22">Newman AB</searchLink>; Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Pereira+T%22">Pereira T</searchLink>; Department of Tecnologia, Polytechnic University of Coimbra, Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Maki-Petaja+K%22">Maki-Petaja K</searchLink>; Division of Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Shipley+M%22">Shipley M</searchLink>; Institute of Epidemiology and Health Care, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Vasan+RS%22">Vasan RS</searchLink>; Department of Medicine, Boston University, Boston, Massachusetts, USA.; University of Texas Health Science Center, San Antonio, Texas, USA.; NHLBI FHS, Framingham, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Wong+A%22">Wong A</searchLink>; MRC Unit for Lifelong Health and Ageing at UCL, London, UK.<br /><searchLink fieldCode="AU" term="%22Ben-Shlomo+Y%22">Ben-Shlomo Y</searchLink>; Population Health Sciences, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Wilkinson+IB%22">Wilkinson IB</searchLink>; Division of Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, Cambridge, UK.; Cambridge Clinical Trials Unit, Cambridge, UK.
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