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Functional and therapeutic effects of Glabrescione B delivery by liposomes on Hedgehog-dependent tumors.

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Title: Functional and therapeutic effects of Glabrescione B delivery by liposomes on Hedgehog-dependent tumors.
Authors: Infante P; Department of Molecular Medicine, Sapienza University, Rome, Italy., Daniele R; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy., Bottero M; Department of Molecular Medicine, Sapienza University, Rome, Italy., Longo M; Department of Molecular Medicine, Sapienza University, Rome, Italy., Bufalieri F; Department of Molecular Medicine, Sapienza University, Rome, Italy., Lospinoso Severini L; Department of Molecular Medicine, Sapienza University, Rome, Italy., Pesce C; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy., Fragassi A; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy., Gabbia D; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy., Navacci S; Department of Molecular Medicine, Sapienza University, Rome, Italy., Basili I; Institut Curie, PSL Research University, INSERMU1330/CNRS EMR 8001. Children's Oncology Research Unit (CONCERT), Paris, France.; CNRS EMR 8001. Children's Oncology Research Unit (CONCERT), Université Paris Sud, Université Paris-Saclay, INSERMU1330, Paris, France.; Istituto Pasteur-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy., Adabbo G; Department of Molecular Medicine, Sapienza University, Rome, Italy., Cammarone S; Dipartimento Di Chimica E Tecnologie del Farmaco, Sapienza University, Rome, Italy., Cianfoni G; Dipartimento Di Chimica E Tecnologie del Farmaco, Sapienza University, Rome, Italy., Ghirga F; Dipartimento Di Chimica E Tecnologie del Farmaco, Sapienza University, Rome, Italy., Mori M; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100, Siena, Italy., De Martin S; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy., Mancuso M; Division of Biotechnologies, Italian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA), 00123, Rome, Italy., Caliceti P; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy., Pazzaglia S; Division of Biotechnologies, Italian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA), 00123, Rome, Italy., Salmaso S; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy. stefano.salmaso@unipd.it., Di Marcotullio L; Department of Molecular Medicine, Sapienza University, Rome, Italy. lucia.dimarcotullio@uniroma1.it.; Istituto Pasteur-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy. lucia.dimarcotullio@uniroma1.it.
Source: Drug delivery and translational research [Drug Deliv Transl Res] 2026 Jul; Vol. 16 (7), pp. 2439-2455. Date of Electronic Publication: 2025 Dec 16.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101540061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2190-3948 (Electronic) Linking ISSN: 2190393X NLM ISO Abbreviation: Drug Deliv Transl Res Subsets: MEDLINE
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  Data: Functional and therapeutic effects of Glabrescione B delivery by liposomes on Hedgehog-dependent tumors.
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  Data: <searchLink fieldCode="AU" term="%22Infante+P%22">Infante P</searchLink>; Department of Molecular Medicine, Sapienza University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Daniele+R%22">Daniele R</searchLink>; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Bottero+M%22">Bottero M</searchLink>; Department of Molecular Medicine, Sapienza University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Longo+M%22">Longo M</searchLink>; Department of Molecular Medicine, Sapienza University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Bufalieri+F%22">Bufalieri F</searchLink>; Department of Molecular Medicine, Sapienza University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Lospinoso+Severini+L%22">Lospinoso Severini L</searchLink>; Department of Molecular Medicine, Sapienza University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Pesce+C%22">Pesce C</searchLink>; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Fragassi+A%22">Fragassi A</searchLink>; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Gabbia+D%22">Gabbia D</searchLink>; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Navacci+S%22">Navacci S</searchLink>; Department of Molecular Medicine, Sapienza University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Basili+I%22">Basili I</searchLink>; Institut Curie, PSL Research University, INSERMU1330/CNRS EMR 8001. Children's Oncology Research Unit (CONCERT), Paris, France.; CNRS EMR 8001. Children's Oncology Research Unit (CONCERT), Université Paris Sud, Université Paris-Saclay, INSERMU1330, Paris, France.; Istituto Pasteur-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Adabbo+G%22">Adabbo G</searchLink>; Department of Molecular Medicine, Sapienza University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Cammarone+S%22">Cammarone S</searchLink>; Dipartimento Di Chimica E Tecnologie del Farmaco, Sapienza University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Cianfoni+G%22">Cianfoni G</searchLink>; Dipartimento Di Chimica E Tecnologie del Farmaco, Sapienza University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ghirga+F%22">Ghirga F</searchLink>; Dipartimento Di Chimica E Tecnologie del Farmaco, Sapienza University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Mori+M%22">Mori M</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22De+Martin+S%22">De Martin S</searchLink>; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Mancuso+M%22">Mancuso M</searchLink>; Division of Biotechnologies, Italian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA), 00123, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Caliceti+P%22">Caliceti P</searchLink>; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Pazzaglia+S%22">Pazzaglia S</searchLink>; Division of Biotechnologies, Italian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA), 00123, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Salmaso+S%22">Salmaso S</searchLink>; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy. stefano.salmaso@unipd.it.<br /><searchLink fieldCode="AU" term="%22Di+Marcotullio+L%22">Di Marcotullio L</searchLink>; Department of Molecular Medicine, Sapienza University, Rome, Italy. lucia.dimarcotullio@uniroma1.it.; Istituto Pasteur-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy. lucia.dimarcotullio@uniroma1.it.
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  Data: <searchLink fieldCode="JN" term="%22101540061%22">Drug delivery and translational research</searchLink> [Drug Deliv Transl Res] 2026 Jul; Vol. 16 (7), pp. 2439-2455. <i>Date of Electronic Publication: </i>2025 Dec 16.
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