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Model-informed development of bacteriophage therapy: bridging in vitro and in vivo efficacy against multidrug-resistant Pseudomonas aeruginosa.

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Title: Model-informed development of bacteriophage therapy: bridging in vitro and in vivo efficacy against multidrug-resistant Pseudomonas aeruginosa.
Authors: Cha JS; Department of Pharmacology, Yonsei University, Seodaemun-gu, Seoul, Republic of Korea.; Department of Pharmacology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seodaemun-gu, Seoul, Republic of Korea., Kim K; Microbiotix Co., Ltd, Seoul, Republic of Korea., You HJ; Microbiotix Co., Ltd, Seoul, Republic of Korea., Kim D; Microbiotix Co., Ltd, Seoul, Republic of Korea., Park HH; Microbiotix Co., Ltd, Seoul, Republic of Korea., Heo S; Microbiotix Co., Ltd, Seoul, Republic of Korea., Kim CO; Department of Clinical Pharmacology, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea., Jin BH; Department of Clinical Pharmacology, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea., Yong D; Microbiotix Co., Ltd, Seoul, Republic of Korea.; Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Republic of Korea., Chae D; Department of Pharmacology, Yonsei University, Seodaemun-gu, Seoul, Republic of Korea.; Microbiotix Co., Ltd, Seoul, Republic of Korea.
Source: MSystems [mSystems] 2025 Dec 17; Vol. 10 (12), pp. e0138425. Date of Electronic Publication: 2025 Nov 13.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101680636 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2379-5077 (Electronic) Linking ISSN: 23795077 NLM ISO Abbreviation: mSystems Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Cha+JS%22">Cha JS</searchLink>; Department of Pharmacology, Yonsei University, Seodaemun-gu, Seoul, Republic of Korea.; Department of Pharmacology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seodaemun-gu, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+K%22">Kim K</searchLink>; Microbiotix Co., Ltd, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22You+HJ%22">You HJ</searchLink>; Microbiotix Co., Ltd, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+D%22">Kim D</searchLink>; Microbiotix Co., Ltd, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+HH%22">Park HH</searchLink>; Microbiotix Co., Ltd, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Heo+S%22">Heo S</searchLink>; Microbiotix Co., Ltd, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+CO%22">Kim CO</searchLink>; Department of Clinical Pharmacology, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jin+BH%22">Jin BH</searchLink>; Department of Clinical Pharmacology, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yong+D%22">Yong D</searchLink>; Microbiotix Co., Ltd, Seoul, Republic of Korea.; Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chae+D%22">Chae D</searchLink>; Department of Pharmacology, Yonsei University, Seodaemun-gu, Seoul, Republic of Korea.; Microbiotix Co., Ltd, Seoul, Republic of Korea.
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              Text: 2025 Dec 17
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