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Biofilms in clinical infection: pathophysiology, diagnosis, and the evolving therapeutic landscape.

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Title: Biofilms in clinical infection: pathophysiology, diagnosis, and the evolving therapeutic landscape.
Authors: Domouchtsidou A; Microbiology Department, 'Saint Savvas' Oncology Hospital, Athens, Greece., Ioannou P; School of Medicine, University of Crete, Heraklion, Greece., Lianou A; Neonatal Intensive Care Unit, 'Agios Panteleimon' General Hospital of Nikea, Piraeus, Greece., Tsante KA; Department of Biomedical Sciences, University of West Attica, Athens, Greece., Tsakri D; Department of Microbiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece., Bonova E; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Baliou S; Laboratory of Toxicology, School of Medicine, University of Crete, Heraklion, Greece., Fortis SP; Laboratory of Reliability and Quality Control in Laboratory Hematology (HemQcR), Department of Biomedical Sciences, School of Health & Caring Sciences, University of West Attica, Athens, Greece., Chaldoupis AE; Laboratory of Haematology and Blood Bank Unit, School of Medicine, 'Attiko' Hospital, National and Kapodistrian University of Athens, Athens, Greece., Samonis G; School of Medicine, University of Crete, Heraklion, Greece.; First Department of Medical Oncology, Metropolitan Hospital of Neon Faliron, Athens, Greece., Koutserimpas C; School of Rehabilitation Health Sciences, University of Patras, Patras, Greece., Sokou R; Neonatal Department, Aretaieio Hospital, National and Kapodistrian University of Athens, Athens, Greece., Papadopoulos DV; Second Department of Orthopaedic Surgery, School of Medicine, Konstantopouleio General Hospital, National and Kapodistrian University of Athens, Athens, Greece., Tsantes AG; Microbiology Department, 'Saint Savvas' Oncology Hospital, Athens, Greece.; Laboratory of Haematology and Blood Bank Unit, School of Medicine, 'Attiko' Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Source: Journal of clinical microbiology [J Clin Microbiol] 2026 Mar 11; Vol. 64 (3), pp. e0104225. Date of Electronic Publication: 2025 Dec 17.
Publication Type: Journal Article; Review
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 7505564 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-660X (Electronic) Linking ISSN: 00951137 NLM ISO Abbreviation: J Clin Microbiol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Domouchtsidou+A%22">Domouchtsidou A</searchLink>; Microbiology Department, 'Saint Savvas' Oncology Hospital, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Ioannou+P%22">Ioannou P</searchLink>; School of Medicine, University of Crete, Heraklion, Greece.<br /><searchLink fieldCode="AU" term="%22Lianou+A%22">Lianou A</searchLink>; Neonatal Intensive Care Unit, 'Agios Panteleimon' General Hospital of Nikea, Piraeus, Greece.<br /><searchLink fieldCode="AU" term="%22Tsante+KA%22">Tsante KA</searchLink>; Department of Biomedical Sciences, University of West Attica, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Tsakri+D%22">Tsakri D</searchLink>; Department of Microbiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Bonova+E%22">Bonova E</searchLink>; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Baliou+S%22">Baliou S</searchLink>; Laboratory of Toxicology, School of Medicine, University of Crete, Heraklion, Greece.<br /><searchLink fieldCode="AU" term="%22Fortis+SP%22">Fortis SP</searchLink>; Laboratory of Reliability and Quality Control in Laboratory Hematology (HemQcR), Department of Biomedical Sciences, School of Health & Caring Sciences, University of West Attica, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Chaldoupis+AE%22">Chaldoupis AE</searchLink>; Laboratory of Haematology and Blood Bank Unit, School of Medicine, 'Attiko' Hospital, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Samonis+G%22">Samonis G</searchLink>; School of Medicine, University of Crete, Heraklion, Greece.; First Department of Medical Oncology, Metropolitan Hospital of Neon Faliron, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Koutserimpas+C%22">Koutserimpas C</searchLink>; School of Rehabilitation Health Sciences, University of Patras, Patras, Greece.<br /><searchLink fieldCode="AU" term="%22Sokou+R%22">Sokou R</searchLink>; Neonatal Department, Aretaieio Hospital, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Papadopoulos+DV%22">Papadopoulos DV</searchLink>; Second Department of Orthopaedic Surgery, School of Medicine, Konstantopouleio General Hospital, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Tsantes+AG%22">Tsantes AG</searchLink>; Microbiology Department, 'Saint Savvas' Oncology Hospital, Athens, Greece.; Laboratory of Haematology and Blood Bank Unit, School of Medicine, 'Attiko' Hospital, National and Kapodistrian University of Athens, Athens, Greece.
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