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The pathogenesis of therapy-related myeloid neoplasms from TP53-mutant clonal hematopoiesis.

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Title: The pathogenesis of therapy-related myeloid neoplasms from TP53-mutant clonal hematopoiesis.
Authors: Fullin J; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland., Topçu E; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland., Zielińska KA; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland., Schimmer RR; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland., Klemm N; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland., Koch C; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland., Caiado F; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland., Lock M; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland., Doerdelmann C; Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland., Bühler MM; Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland., Tchinda J; Laboratory for Oncology, Children's Hospital Zurich, Zurich, Switzerland., Kurppa KJ; Institute of Biomedicine and Medicity Research Laboratories, University of Turku, Turku, Finland., Borsig L; Department of Physiology, University of Zurich, Zurich, Switzerland., Jones PH; Wellcome Sanger Institute, Hinxton, UK.; Department of Oncology, University of Cambridge, Hutchinson Research Centre, Cambridge Biomedical Campus, Cambridge, UK., Lopes M; Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland., Manz MG; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.; Comprehensive Cancer Center Zurich, Zurich, Switzerland., Boettcher S; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland. steffen.boettcher@usz.ch.; Comprehensive Cancer Center Zurich, Zurich, Switzerland. steffen.boettcher@usz.ch.
Source: Leukemia [Leukemia] 2026 Feb; Vol. 40 (2), pp. 279-292. Date of Electronic Publication: 2025 Dec 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE
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  Data: The pathogenesis of therapy-related myeloid neoplasms from TP53-mutant clonal hematopoiesis.
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  Data: <searchLink fieldCode="AU" term="%22Fullin+J%22">Fullin J</searchLink>; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Topçu+E%22">Topçu E</searchLink>; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Zielińska+KA%22">Zielińska KA</searchLink>; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schimmer+RR%22">Schimmer RR</searchLink>; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Klemm+N%22">Klemm N</searchLink>; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Koch+C%22">Koch C</searchLink>; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Caiado+F%22">Caiado F</searchLink>; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lock+M%22">Lock M</searchLink>; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Doerdelmann+C%22">Doerdelmann C</searchLink>; Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bühler+MM%22">Bühler MM</searchLink>; Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Tchinda+J%22">Tchinda J</searchLink>; Laboratory for Oncology, Children's Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kurppa+KJ%22">Kurppa KJ</searchLink>; Institute of Biomedicine and Medicity Research Laboratories, University of Turku, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Borsig+L%22">Borsig L</searchLink>; Department of Physiology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Jones+PH%22">Jones PH</searchLink>; Wellcome Sanger Institute, Hinxton, UK.; Department of Oncology, University of Cambridge, Hutchinson Research Centre, Cambridge Biomedical Campus, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Lopes+M%22">Lopes M</searchLink>; Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Manz+MG%22">Manz MG</searchLink>; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.; Comprehensive Cancer Center Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Boettcher+S%22">Boettcher S</searchLink>; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland. steffen.boettcher@usz.ch.; Comprehensive Cancer Center Zurich, Zurich, Switzerland. steffen.boettcher@usz.ch.
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  Data: <searchLink fieldCode="JN" term="%228704895%22">Leukemia</searchLink> [Leukemia] 2026 Feb; Vol. 40 (2), pp. 279-292. <i>Date of Electronic Publication: </i>2025 Dec 17.
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