View in EDS

Endogenous Osteocyte-Osteoclast Signaling Enables Growth Factor-Free Bone Remodeling, Drug Response, and Cancer Invasion in a Nanoscale Calcified Bone-on-a-Chip Model.

Saved in:
Bibliographic Details
Title: Endogenous Osteocyte-Osteoclast Signaling Enables Growth Factor-Free Bone Remodeling, Drug Response, and Cancer Invasion in a Nanoscale Calcified Bone-on-a-Chip Model.
Authors: Sousa MGC; Knight Cancer Precision Biofabrication Hub, Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.; Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA., Athirasala A; Knight Cancer Precision Biofabrication Hub, Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.; Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA., Roth DM; Knight Cancer Precision Biofabrication Hub, Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.; Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA., Fraga MAA; Department of Restorative Dentistry, Faculdade de Odontologia de Piracicaba (FOP), Universidade Estadual de Campinas, Piracicaba, São Paulo, Brazil., Vignolo SM; Knight Cancer Precision Biofabrication Hub, Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.; Division of Oncological Sciences, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.; Department of Biomedical Engineering, School of Medicine, Oregon Health & Science University, Portland, Oregon, USA., Doe A; Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA., Lee J; Precision oncology, Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon, USA., Romanowicz GE; Knight Campus for Accelerating Scientific Impact, University of Oregon, Eugene, Oregon, USA., Nguyen JV; Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA., Lin ASP; Department of Restorative Dentistry, Faculdade de Odontologia de Piracicaba (FOP), Universidade Estadual de Campinas, Piracicaba, São Paulo, Brazil., Franca CM; Knight Cancer Precision Biofabrication Hub, Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.; Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA., Guldberg RE; Knight Campus for Accelerating Scientific Impact, University of Oregon, Eugene, Oregon, USA., Bertassoni LE; Knight Cancer Precision Biofabrication Hub, Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.; Division of Oncological Sciences, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.; Center for Regenerative Medicine, School of Medicine, Oregon Health & Science University, Portland, Oregon, USA.; Department of Biomedical Engineering, School of Medicine, Oregon Health & Science University, Portland, Oregon, USA.; Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Dec 11. Date of Electronic Publication: 2025 Dec 11.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41409144
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Endogenous Osteocyte-Osteoclast Signaling Enables Growth Factor-Free Bone Remodeling, Drug Response, and Cancer Invasion in a Nanoscale Calcified Bone-on-a-Chip Model.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Sousa+MGC%22">Sousa MGC</searchLink>; Knight Cancer Precision Biofabrication Hub, Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.; Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Athirasala+A%22">Athirasala A</searchLink>; Knight Cancer Precision Biofabrication Hub, Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.; Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Roth+DM%22">Roth DM</searchLink>; Knight Cancer Precision Biofabrication Hub, Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.; Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Fraga+MAA%22">Fraga MAA</searchLink>; Department of Restorative Dentistry, Faculdade de Odontologia de Piracicaba (FOP), Universidade Estadual de Campinas, Piracicaba, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Vignolo+SM%22">Vignolo SM</searchLink>; Knight Cancer Precision Biofabrication Hub, Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.; Division of Oncological Sciences, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.; Department of Biomedical Engineering, School of Medicine, Oregon Health & Science University, Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Doe+A%22">Doe A</searchLink>; Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Precision oncology, Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Romanowicz+GE%22">Romanowicz GE</searchLink>; Knight Campus for Accelerating Scientific Impact, University of Oregon, Eugene, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+JV%22">Nguyen JV</searchLink>; Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Lin+ASP%22">Lin ASP</searchLink>; Department of Restorative Dentistry, Faculdade de Odontologia de Piracicaba (FOP), Universidade Estadual de Campinas, Piracicaba, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Franca+CM%22">Franca CM</searchLink>; Knight Cancer Precision Biofabrication Hub, Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.; Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Guldberg+RE%22">Guldberg RE</searchLink>; Knight Campus for Accelerating Scientific Impact, University of Oregon, Eugene, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Bertassoni+LE%22">Bertassoni LE</searchLink>; Knight Cancer Precision Biofabrication Hub, Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.; Division of Oncological Sciences, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.; Center for Regenerative Medicine, School of Medicine, Oregon Health & Science University, Portland, Oregon, USA.; Department of Biomedical Engineering, School of Medicine, Oregon Health & Science University, Portland, Oregon, USA.; Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2025 Dec 11. <i>Date of Electronic Publication: </i>2025 Dec 11.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Preprint
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41409144
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.64898/2025.12.08.693047
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Endogenous Osteocyte-Osteoclast Signaling Enables Growth Factor-Free Bone Remodeling, Drug Response, and Cancer Invasion in a Nanoscale Calcified Bone-on-a-Chip Model.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Sousa MGC
      – PersonEntity:
          Name:
            NameFull: Athirasala A
      – PersonEntity:
          Name:
            NameFull: Roth DM
      – PersonEntity:
          Name:
            NameFull: Fraga MAA
      – PersonEntity:
          Name:
            NameFull: Vignolo SM
      – PersonEntity:
          Name:
            NameFull: Doe A
      – PersonEntity:
          Name:
            NameFull: Lee J
      – PersonEntity:
          Name:
            NameFull: Romanowicz GE
      – PersonEntity:
          Name:
            NameFull: Nguyen JV
      – PersonEntity:
          Name:
            NameFull: Lin ASP
      – PersonEntity:
          Name:
            NameFull: Franca CM
      – PersonEntity:
          Name:
            NameFull: Guldberg RE
      – PersonEntity:
          Name:
            NameFull: Bertassoni LE
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 11
              M: 12
              Text: 2025 Dec 11
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2692-8205
          Titles:
            – TitleFull: BioRxiv : the preprint server for biology
              Type: main
ResultId 1