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Co-exposure to PFAS and hydroxylated PCBs is associated with increased odds of multiple sclerosis.

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Title: Co-exposure to PFAS and hydroxylated PCBs is associated with increased odds of multiple sclerosis.
Authors: Vaivade A; Department of Medical Sciences, Uppsala University, Sweden., Sreenivasan AP; Department of Medical Sciences, Uppsala University, Sweden., Erngren I; Department of Medical Sciences, Uppsala University, Sweden., Freyhult E; Department of Cell and Molecular Biology, National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Uppsala University, Sweden., Emami Khoonsari P; Department of Medical Sciences, Uppsala University, Sweden; Department of Biochemistry and Biophysics, National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Stockholm University, Stockholm, Sweden., Siljebo J; Department of Medical Sciences, Uppsala University, Sweden., Al-Grety A; Department of Medical Sciences, Uppsala University, Sweden., Carlsson H; Department of Medical Sciences, Uppsala University, Sweden., Åkerfeldt T; Department of Medical Sciences, Uppsala University, Sweden., Spjuth O; Department of Pharmaceutical Biosciences, Uppsala University, Sweden., Hedström AK; Department of Clinical Neuroscience, Karolinska Institutet, Sweden., Kockum I; Department of Clinical Neuroscience, Karolinska Institutet, Sweden; The Karolinska Neuroimmunology & Multiple Sclerosis Centre, Centrum for Molecular Medicine, Karolinska University Hospital, Sweden; Academic Specialist Center, Stockholm 113 65, Sweden., Alfredsson L; Department of Clinical Neuroscience, Karolinska Institutet, Sweden; Institute of Environmental Medicine, Karolinska Institutet, Sweden; Centre for Occupational and Environmental Medicine, Region Stockholm, Sweden., Olsson T; Department of Clinical Neuroscience, Karolinska Institutet, Sweden; The Karolinska Neuroimmunology & Multiple Sclerosis Centre, Centrum for Molecular Medicine, Karolinska University Hospital, Sweden; Academic Specialist Center, Stockholm 113 65, Sweden., Burman J; Department of Medical Sciences, Uppsala University, Sweden., Kultima K; Department of Medical Sciences, Uppsala University, Sweden. Electronic address: Kim.Kultima@medsci.uu.se.
Source: Environment international [Environ Int] 2026 Jan; Vol. 207, pp. 109993. Date of Electronic Publication: 2025 Dec 11.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 7807270 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6750 (Electronic) Linking ISSN: 01604120 NLM ISO Abbreviation: Environ Int Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Co-exposure to PFAS and hydroxylated PCBs is associated with increased odds of multiple sclerosis.
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  Data: <searchLink fieldCode="AU" term="%22Vaivade+A%22">Vaivade A</searchLink>; Department of Medical Sciences, Uppsala University, Sweden.<br /><searchLink fieldCode="AU" term="%22Sreenivasan+AP%22">Sreenivasan AP</searchLink>; Department of Medical Sciences, Uppsala University, Sweden.<br /><searchLink fieldCode="AU" term="%22Erngren+I%22">Erngren I</searchLink>; Department of Medical Sciences, Uppsala University, Sweden.<br /><searchLink fieldCode="AU" term="%22Freyhult+E%22">Freyhult E</searchLink>; Department of Cell and Molecular Biology, National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Uppsala University, Sweden.<br /><searchLink fieldCode="AU" term="%22Emami+Khoonsari+P%22">Emami Khoonsari P</searchLink>; Department of Medical Sciences, Uppsala University, Sweden; Department of Biochemistry and Biophysics, National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Stockholm University, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Siljebo+J%22">Siljebo J</searchLink>; Department of Medical Sciences, Uppsala University, Sweden.<br /><searchLink fieldCode="AU" term="%22Al-Grety+A%22">Al-Grety A</searchLink>; Department of Medical Sciences, Uppsala University, Sweden.<br /><searchLink fieldCode="AU" term="%22Carlsson+H%22">Carlsson H</searchLink>; Department of Medical Sciences, Uppsala University, Sweden.<br /><searchLink fieldCode="AU" term="%22Åkerfeldt+T%22">Åkerfeldt T</searchLink>; Department of Medical Sciences, Uppsala University, Sweden.<br /><searchLink fieldCode="AU" term="%22Spjuth+O%22">Spjuth O</searchLink>; Department of Pharmaceutical Biosciences, Uppsala University, Sweden.<br /><searchLink fieldCode="AU" term="%22Hedström+AK%22">Hedström AK</searchLink>; Department of Clinical Neuroscience, Karolinska Institutet, Sweden.<br /><searchLink fieldCode="AU" term="%22Kockum+I%22">Kockum I</searchLink>; Department of Clinical Neuroscience, Karolinska Institutet, Sweden; The Karolinska Neuroimmunology & Multiple Sclerosis Centre, Centrum for Molecular Medicine, Karolinska University Hospital, Sweden; Academic Specialist Center, Stockholm 113 65, Sweden.<br /><searchLink fieldCode="AU" term="%22Alfredsson+L%22">Alfredsson L</searchLink>; Department of Clinical Neuroscience, Karolinska Institutet, Sweden; Institute of Environmental Medicine, Karolinska Institutet, Sweden; Centre for Occupational and Environmental Medicine, Region Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Olsson+T%22">Olsson T</searchLink>; Department of Clinical Neuroscience, Karolinska Institutet, Sweden; The Karolinska Neuroimmunology & Multiple Sclerosis Centre, Centrum for Molecular Medicine, Karolinska University Hospital, Sweden; Academic Specialist Center, Stockholm 113 65, Sweden.<br /><searchLink fieldCode="AU" term="%22Burman+J%22">Burman J</searchLink>; Department of Medical Sciences, Uppsala University, Sweden.<br /><searchLink fieldCode="AU" term="%22Kultima+K%22">Kultima K</searchLink>; Department of Medical Sciences, Uppsala University, Sweden. Electronic address: Kim.Kultima@medsci.uu.se.
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  Data: <searchLink fieldCode="JN" term="%227807270%22">Environment international</searchLink> [Environ Int] 2026 Jan; Vol. 207, pp. 109993. <i>Date of Electronic Publication: </i>2025 Dec 11.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>7807270 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-6750 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201604120%22">01604120 </searchLink><i>NLM ISO Abbreviation: </i>Environ Int <i>Subsets: </i>MEDLINE
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        Text: English
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              Text: 2026 Jan
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