[18F]-Fluciclovine or [68Ga]-PSMA-11 Molecular Imaging To Guide Dose Escalation of Salvage Radiotherapy After Radical Prostatectomy for Prostate Cancer: The EMPIRE-2 Trial.

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Title: [18F]-Fluciclovine or [68Ga]-PSMA-11 Molecular Imaging To Guide Dose Escalation of Salvage Radiotherapy After Radical Prostatectomy for Prostate Cancer: The EMPIRE-2 Trial.
Authors: Jani AB; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA. Electronic address: abjani@emory.edu., Dhere VR; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA., Goyal S; Biostatistics Shared Resource, Winship Cancer Institute of Emory University, Atlanta, GA, USA., Schreibmann E; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA., Patel PR; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA., Hershatter B; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA., Shelton JW; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA., Hanasoge S; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA., Sebastian NT; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA., Patel SA; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA., Halkar R; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, USA., Cooper S; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA., Fielder B; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, USA., Abiodun-Ojo OA; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, USA., Lawal I; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, USA., Mushtaq A; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, USA., Master VA; Department of Urology, Emory University, Atlanta, GA, USA., Joshi SS; Department of Urology, Emory University, Atlanta, GA, USA., Kucuk O; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA., Bilen MA; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA., Schuster DM; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, USA.
Source: European urology [Eur Urol] 2026 Apr; Vol. 89 (4), pp. 368-377. Date of Electronic Publication: 2025 Dec 17.
Publication Type: Journal Article; Randomized Controlled Trial; Comparative Study
Journal Info: Publisher: Elsevier Science Country of Publication: Switzerland NLM ID: 7512719 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7560 (Electronic) Linking ISSN: 03022838 NLM ISO Abbreviation: Eur Urol Subsets: MEDLINE
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  Data: [<superscript>18</superscript>F]-Fluciclovine or [<superscript>68</superscript>Ga]-PSMA-11 Molecular Imaging To Guide Dose Escalation of Salvage Radiotherapy After Radical Prostatectomy for Prostate Cancer: The EMPIRE-2 Trial.
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  Data: <searchLink fieldCode="AU" term="%22Jani+AB%22">Jani AB</searchLink>; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA. Electronic address: abjani@emory.edu.<br /><searchLink fieldCode="AU" term="%22Dhere+VR%22">Dhere VR</searchLink>; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Goyal+S%22">Goyal S</searchLink>; Biostatistics Shared Resource, Winship Cancer Institute of Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Schreibmann+E%22">Schreibmann E</searchLink>; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Patel+PR%22">Patel PR</searchLink>; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Hershatter+B%22">Hershatter B</searchLink>; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Shelton+JW%22">Shelton JW</searchLink>; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Hanasoge+S%22">Hanasoge S</searchLink>; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Sebastian+NT%22">Sebastian NT</searchLink>; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Patel+SA%22">Patel SA</searchLink>; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Halkar+R%22">Halkar R</searchLink>; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Cooper+S%22">Cooper S</searchLink>; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Fielder+B%22">Fielder B</searchLink>; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Abiodun-Ojo+OA%22">Abiodun-Ojo OA</searchLink>; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Lawal+I%22">Lawal I</searchLink>; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Mushtaq+A%22">Mushtaq A</searchLink>; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Master+VA%22">Master VA</searchLink>; Department of Urology, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Joshi+SS%22">Joshi SS</searchLink>; Department of Urology, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Kucuk+O%22">Kucuk O</searchLink>; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Bilen+MA%22">Bilen MA</searchLink>; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Schuster+DM%22">Schuster DM</searchLink>; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, USA.
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  Data: <searchLink fieldCode="JN" term="%227512719%22">European urology</searchLink> [Eur Urol] 2026 Apr; Vol. 89 (4), pp. 368-377. <i>Date of Electronic Publication: </i>2025 Dec 17.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>7512719 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-7560 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203022838%22">03022838 </searchLink><i>NLM ISO Abbreviation: </i>Eur Urol <i>Subsets: </i>MEDLINE
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              Text: 2026 Apr
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