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Translational and First-in-Human Positron Emission Tomography Targeting Prostatic Acid Phosphatase in Prostate Cancer Using the Ligand [68Ga]Ga-OncoACP3-DOTA.

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Title: Translational and First-in-Human Positron Emission Tomography Targeting Prostatic Acid Phosphatase in Prostate Cancer Using the Ligand [68Ga]Ga-OncoACP3-DOTA.
Authors: Backhaus P; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany; European Institute of Molecular Imaging, University of Münster, Münster, Germany. Electronic address: philipp.backhaus@ukmuenster.de., Cazzamalli S; Philochem AG, Otelfingen, Switzerland., Oehler S; Philochem AG, Otelfingen, Switzerland., Büther F; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany; European Institute of Molecular Imaging, University of Münster, Münster, Germany., Brosch-Lenz J; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany., Landau F; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany; European Institute of Molecular Imaging, University of Münster, Münster, Germany., Breyholz HJ; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany., Claesener M; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany., Migliorini F; Philochem AG, Otelfingen, Switzerland., Ciamarone A; Philochem AG, Otelfingen, Switzerland., Georgiev T; Philochem AG, Otelfingen, Switzerland., Mock J; Philochem AG, Otelfingen, Switzerland., Ventura D; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany; European Institute of Molecular Imaging, University of Münster, Münster, Germany., Barca C; European Institute of Molecular Imaging, University of Münster, Münster, Germany., Schiefelbein L; European Institute of Molecular Imaging, University of Münster, Münster, Germany., Hermann S; European Institute of Molecular Imaging, University of Münster, Münster, Germany., Schäfers K; European Institute of Molecular Imaging, University of Münster, Münster, Germany., Gierse F; European Institute of Molecular Imaging, University of Münster, Münster, Germany., Bernemann C; Department of Urology, University Hospital Münster, Münster, Germany., Schlack K; Department of Urology, University Hospital Münster, Münster, Germany., Bögemann M; Department of Urology, University Hospital Münster, Münster, Germany., Puca E; Philochem AG, Otelfingen, Switzerland., Schindler P; Department of Radiology, University Hospital Münster, Münster, Germany., Neri D; Philochem AG, Otelfingen, Switzerland., Rahbar K; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany., Schrader AJ; Department of Urology, University Hospital Münster, Münster, Germany., Seifert KE; European Institute of Molecular Imaging, University of Münster, Münster, Germany; Department of Urology, University Hospital Münster, Münster, Germany., Schäfers M; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany; European Institute of Molecular Imaging, University of Münster, Münster, Germany.
Source: European urology [Eur Urol] 2026 Apr; Vol. 89 (4), pp. 305-310. Date of Electronic Publication: 2025 Dec 17.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Switzerland NLM ID: 7512719 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7560 (Electronic) Linking ISSN: 03022838 NLM ISO Abbreviation: Eur Urol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Backhaus+P%22">Backhaus P</searchLink>; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany; European Institute of Molecular Imaging, University of Münster, Münster, Germany. Electronic address: philipp.backhaus@ukmuenster.de.<br /><searchLink fieldCode="AU" term="%22Cazzamalli+S%22">Cazzamalli S</searchLink>; Philochem AG, Otelfingen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Oehler+S%22">Oehler S</searchLink>; Philochem AG, Otelfingen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Büther+F%22">Büther F</searchLink>; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany; European Institute of Molecular Imaging, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Brosch-Lenz+J%22">Brosch-Lenz J</searchLink>; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Landau+F%22">Landau F</searchLink>; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany; European Institute of Molecular Imaging, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Breyholz+HJ%22">Breyholz HJ</searchLink>; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Claesener+M%22">Claesener M</searchLink>; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Migliorini+F%22">Migliorini F</searchLink>; Philochem AG, Otelfingen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ciamarone+A%22">Ciamarone A</searchLink>; Philochem AG, Otelfingen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Georgiev+T%22">Georgiev T</searchLink>; Philochem AG, Otelfingen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mock+J%22">Mock J</searchLink>; Philochem AG, Otelfingen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ventura+D%22">Ventura D</searchLink>; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany; European Institute of Molecular Imaging, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Barca+C%22">Barca C</searchLink>; European Institute of Molecular Imaging, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Schiefelbein+L%22">Schiefelbein L</searchLink>; European Institute of Molecular Imaging, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Hermann+S%22">Hermann S</searchLink>; European Institute of Molecular Imaging, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Schäfers+K%22">Schäfers K</searchLink>; European Institute of Molecular Imaging, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Gierse+F%22">Gierse F</searchLink>; European Institute of Molecular Imaging, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Bernemann+C%22">Bernemann C</searchLink>; Department of Urology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Schlack+K%22">Schlack K</searchLink>; Department of Urology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Bögemann+M%22">Bögemann M</searchLink>; Department of Urology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Puca+E%22">Puca E</searchLink>; Philochem AG, Otelfingen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schindler+P%22">Schindler P</searchLink>; Department of Radiology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Neri+D%22">Neri D</searchLink>; Philochem AG, Otelfingen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rahbar+K%22">Rahbar K</searchLink>; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Schrader+AJ%22">Schrader AJ</searchLink>; Department of Urology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Seifert+KE%22">Seifert KE</searchLink>; European Institute of Molecular Imaging, University of Münster, Münster, Germany; Department of Urology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Schäfers+M%22">Schäfers M</searchLink>; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany; European Institute of Molecular Imaging, University of Münster, Münster, Germany.
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  Data: <searchLink fieldCode="JN" term="%227512719%22">European urology</searchLink> [Eur Urol] 2026 Apr; Vol. 89 (4), pp. 305-310. <i>Date of Electronic Publication: </i>2025 Dec 17.
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