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Nucleophosmin supports WNT-driven hyperproliferation and tumor initiation.

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Title: Nucleophosmin supports WNT-driven hyperproliferation and tumor initiation.
Authors: Kanellos G; Cancer Research UK Scotland Institute, Glasgow, UK. g.kanellos@crukscotlandinstitute.ac.uk., Giacomelli C; Cancer Research UK Scotland Institute, Glasgow, UK., Raven A; Cancer Research UK Scotland Institute, Glasgow, UK., Vlahov N; Cancer Research UK Scotland Institute, Glasgow, UK., Jin H; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Herviou P; Cancer Research UK Scotland Institute, Glasgow, UK., Malla SB; Cancer Research UK Scotland Institute, Glasgow, UK.; The Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Nasreddin N; Cancer Research UK Scotland Institute, Glasgow, UK., Centeno PP; Cancer Research UK Scotland Institute, Glasgow, UK., Alexandrou C; Cancer Research UK Scotland Institute, Glasgow, UK., Gilroy K; Cancer Research UK Scotland Institute, Glasgow, UK., Baird RL; Cancer Research UK Scotland Institute, Glasgow, UK., Pennel K; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Munro J; Cancer Research UK Scotland Institute, Glasgow, UK., Waldron JA; Cancer Research UK Scotland Institute, Glasgow, UK., Hall H; Cancer Research UK Scotland Institute, Glasgow, UK., Officer-Jones L; Cancer Research UK Scotland Institute, Glasgow, UK., Bryson S; Cancer Research UK Scotland Institute, Glasgow, UK., Strathdee D; Cancer Research UK Scotland Institute, Glasgow, UK., Lilla S; Cancer Research UK Scotland Institute, Glasgow, UK., Zanivan S; Cancer Research UK Scotland Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK.; Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Morrison V; Cancer Research UK Scotland Institute, Glasgow, UK., Nixon C; Cancer Research UK Scotland Institute, Glasgow, UK., Ridgway RA; Cancer Research UK Scotland Institute, Glasgow, UK., Miller C; Cancer Research UK Scotland Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Knight JRP; Cancer Research UK Scotland Institute, Glasgow, UK.; Division of Cancer Sciences, University of Manchester, Manchester, UK., Campbell AD; Cancer Research UK Scotland Institute, Glasgow, UK., Dunne PD; Cancer Research UK Scotland Institute, Glasgow, UK.; The Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Le Quesne J; Cancer Research UK Scotland Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK.; Department of Histopathology, Queen Elizabeth University Hospital, Glasgow, UK., Edwards J; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Park PJ; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Bushell M; Cancer Research UK Scotland Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Sansom OJ; Cancer Research UK Scotland Institute, Glasgow, UK. o.sansom@crukscotlandinstitute.ac.uk.; School of Cancer Sciences, University of Glasgow, Glasgow, UK. o.sansom@crukscotlandinstitute.ac.uk.
Source: Nature genetics [Nat Genet] 2026 Jan; Vol. 58 (1), pp. 100-115. Date of Electronic Publication: 2025 Dec 18.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE
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  Data: Nucleophosmin supports WNT-driven hyperproliferation and tumor initiation.
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  Data: <searchLink fieldCode="AU" term="%22Kanellos+G%22">Kanellos G</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK. g.kanellos@crukscotlandinstitute.ac.uk.<br /><searchLink fieldCode="AU" term="%22Giacomelli+C%22">Giacomelli C</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Raven+A%22">Raven A</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Vlahov+N%22">Vlahov N</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Jin+H%22">Jin H</searchLink>; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Herviou+P%22">Herviou P</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Malla+SB%22">Malla SB</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.; The Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Nasreddin+N%22">Nasreddin N</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Centeno+PP%22">Centeno PP</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Alexandrou+C%22">Alexandrou C</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Gilroy+K%22">Gilroy K</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Baird+RL%22">Baird RL</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Pennel+K%22">Pennel K</searchLink>; School of Cancer Sciences, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Munro+J%22">Munro J</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Waldron+JA%22">Waldron JA</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Hall+H%22">Hall H</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Officer-Jones+L%22">Officer-Jones L</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Bryson+S%22">Bryson S</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Strathdee+D%22">Strathdee D</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Lilla+S%22">Lilla S</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Zanivan+S%22">Zanivan S</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK.; Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Morrison+V%22">Morrison V</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Nixon+C%22">Nixon C</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Ridgway+RA%22">Ridgway RA</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Miller+C%22">Miller C</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Knight+JRP%22">Knight JRP</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.; Division of Cancer Sciences, University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Campbell+AD%22">Campbell AD</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Dunne+PD%22">Dunne PD</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.; The Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Le+Quesne+J%22">Le Quesne J</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK.; Department of Histopathology, Queen Elizabeth University Hospital, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Edwards+J%22">Edwards J</searchLink>; School of Cancer Sciences, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Park+PJ%22">Park PJ</searchLink>; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bushell+M%22">Bushell M</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Sansom+OJ%22">Sansom OJ</searchLink>; Cancer Research UK Scotland Institute, Glasgow, UK. o.sansom@crukscotlandinstitute.ac.uk.; School of Cancer Sciences, University of Glasgow, Glasgow, UK. o.sansom@crukscotlandinstitute.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%229216904%22">Nature genetics</searchLink> [Nat Genet] 2026 Jan; Vol. 58 (1), pp. 100-115. <i>Date of Electronic Publication: </i>2025 Dec 18.
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