Diabetes increases SCO-spondin secretion but reduces Wnt5a interaction with ependymal cells, inducing ciliary stiffness and Frizzled-2 downregulation.
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| Title: | Diabetes increases SCO-spondin secretion but reduces Wnt5a interaction with ependymal cells, inducing ciliary stiffness and Frizzled-2 downregulation. |
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| Authors: | Cifuentes M; Department of Cell Biology, Genetics and Physiology, University of Malaga, Malaga, Spain., Ramírez E; Laboratory of Neurobiology and Stem Cells, NeuroCellT, Department of Cellular Biology, Faculty of Biological Sciences, University of Concepción, Concepción, Chile., Barahona MJ; Laboratory of Neurobiology and Stem Cells, NeuroCellT, Department of Cellular Biology, Faculty of Biological Sciences, University of Concepción, Concepción, Chile; Facultad de Ciencias, Universidad San Sebastián, Concepción, Chile., Martínez F; Laboratory of Neurobiology and Stem Cells, NeuroCellT, Department of Cellular Biology, Faculty of Biological Sciences, University of Concepción, Concepción, Chile., de Lima I; Laboratory of Neurobiology and Stem Cells, NeuroCellT, Department of Cellular Biology, Faculty of Biological Sciences, University of Concepción, Concepción, Chile., Ferrada L; Center for Advanced Microscopy CMA BIO BIO, University of Concepción, Concepción, Chile., Bertinat R; Laboratory of Neurobiology and Stem Cells, NeuroCellT, Department of Cellular Biology, Faculty of Biological Sciences, University of Concepción, Concepción, Chile., Ávila F; Universidad de Talca, Talca, Chile., Saldivia N; Laboratory of Neurobiology and Stem Cells, NeuroCellT, Department of Cellular Biology, Faculty of Biological Sciences, University of Concepción, Concepción, Chile., Pérez-Martín M; Department of Cell Biology, Genetics and Physiology, University of Malaga, Malaga, Spain; Biomedical Research Institute of Malaga and Nanomedicine Platform-IBIMA, Bionand Platform, 29590 Malaga, Spain., Oliver-Martin B; Biomedical Research Institute of Malaga and Nanomedicine Platform-IBIMA, Bionand Platform, 29590 Malaga, Spain; Regional University Hospital of Malaga, Malaga, Spain., Ciano-Petersen N; Biomedical Research Institute of Malaga and Nanomedicine Platform-IBIMA, Bionand Platform, 29590 Malaga, Spain; Regional University Hospital of Malaga, Malaga, Spain., Fernández-Arjona MDM; Biomedical Research Institute of Malaga and Nanomedicine Platform-IBIMA, Bionand Platform, 29590 Malaga, Spain; Regional University Hospital of Malaga, Malaga, Spain., Salazar K; Laboratory of Neurobiology and Stem Cells, NeuroCellT, Department of Cellular Biology, Faculty of Biological Sciences, University of Concepción, Concepción, Chile; Center for Advanced Microscopy CMA BIO BIO, University of Concepción, Concepción, Chile. Electronic address: katterinsalazar@udec.cl., Nualart F; Laboratory of Neurobiology and Stem Cells, NeuroCellT, Department of Cellular Biology, Faculty of Biological Sciences, University of Concepción, Concepción, Chile; Center for Advanced Microscopy CMA BIO BIO, University of Concepción, Concepción, Chile. Electronic address: frnualart@udec.cl. |
| Source: | Neurobiology of disease [Neurobiol Dis] 2026 Jan; Vol. 218, pp. 107225. Date of Electronic Publication: 2025 Dec 17. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41419028 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Diabetes increases SCO-spondin secretion but reduces Wnt5a interaction with ependymal cells, inducing ciliary stiffness and Frizzled-2 downregulation. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Cifuentes+M%22">Cifuentes M</searchLink>; Department of Cell Biology, Genetics and Physiology, University of Malaga, Malaga, Spain.<br /><searchLink fieldCode="AU" term="%22Ramírez+E%22">Ramírez E</searchLink>; Laboratory of Neurobiology and Stem Cells, NeuroCellT, Department of Cellular Biology, Faculty of Biological Sciences, University of Concepción, Concepción, Chile.<br /><searchLink fieldCode="AU" term="%22Barahona+MJ%22">Barahona MJ</searchLink>; Laboratory of Neurobiology and Stem Cells, NeuroCellT, Department of Cellular Biology, Faculty of Biological Sciences, University of Concepción, Concepción, Chile; Facultad de Ciencias, Universidad San Sebastián, Concepción, Chile.<br /><searchLink fieldCode="AU" term="%22Martínez+F%22">Martínez F</searchLink>; Laboratory of Neurobiology and Stem Cells, NeuroCellT, Department of Cellular Biology, Faculty of Biological Sciences, University of Concepción, Concepción, Chile.<br /><searchLink fieldCode="AU" term="%22de+Lima+I%22">de Lima I</searchLink>; Laboratory of Neurobiology and Stem Cells, NeuroCellT, Department of Cellular Biology, Faculty of Biological Sciences, University of Concepción, Concepción, Chile.<br /><searchLink fieldCode="AU" term="%22Ferrada+L%22">Ferrada L</searchLink>; Center for Advanced Microscopy CMA BIO BIO, University of Concepción, Concepción, Chile.<br /><searchLink fieldCode="AU" term="%22Bertinat+R%22">Bertinat R</searchLink>; Laboratory of Neurobiology and Stem Cells, NeuroCellT, Department of Cellular Biology, Faculty of Biological Sciences, University of Concepción, Concepción, Chile.<br /><searchLink fieldCode="AU" term="%22Ávila+F%22">Ávila F</searchLink>; Universidad de Talca, Talca, Chile.<br /><searchLink fieldCode="AU" term="%22Saldivia+N%22">Saldivia N</searchLink>; Laboratory of Neurobiology and Stem Cells, NeuroCellT, Department of Cellular Biology, Faculty of Biological Sciences, University of Concepción, Concepción, Chile.<br /><searchLink fieldCode="AU" term="%22Pérez-Martín+M%22">Pérez-Martín M</searchLink>; Department of Cell Biology, Genetics and Physiology, University of Malaga, Malaga, Spain; Biomedical Research Institute of Malaga and Nanomedicine Platform-IBIMA, Bionand Platform, 29590 Malaga, Spain.<br /><searchLink fieldCode="AU" term="%22Oliver-Martin+B%22">Oliver-Martin B</searchLink>; Biomedical Research Institute of Malaga and Nanomedicine Platform-IBIMA, Bionand Platform, 29590 Malaga, Spain; Regional University Hospital of Malaga, Malaga, Spain.<br /><searchLink fieldCode="AU" term="%22Ciano-Petersen+N%22">Ciano-Petersen N</searchLink>; Biomedical Research Institute of Malaga and Nanomedicine Platform-IBIMA, Bionand Platform, 29590 Malaga, Spain; Regional University Hospital of Malaga, Malaga, Spain.<br /><searchLink fieldCode="AU" term="%22Fernández-Arjona+MDM%22">Fernández-Arjona MDM</searchLink>; Biomedical Research Institute of Malaga and Nanomedicine Platform-IBIMA, Bionand Platform, 29590 Malaga, Spain; Regional University Hospital of Malaga, Malaga, Spain.<br /><searchLink fieldCode="AU" term="%22Salazar+K%22">Salazar K</searchLink>; Laboratory of Neurobiology and Stem Cells, NeuroCellT, Department of Cellular Biology, Faculty of Biological Sciences, University of Concepción, Concepción, Chile; Center for Advanced Microscopy CMA BIO BIO, University of Concepción, Concepción, Chile. Electronic address: katterinsalazar@udec.cl.<br /><searchLink fieldCode="AU" term="%22Nualart+F%22">Nualart F</searchLink>; Laboratory of Neurobiology and Stem Cells, NeuroCellT, Department of Cellular Biology, Faculty of Biological Sciences, University of Concepción, Concepción, Chile; Center for Advanced Microscopy CMA BIO BIO, University of Concepción, Concepción, Chile. Electronic address: frnualart@udec.cl. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229500169%22">Neurobiology of disease</searchLink> [Neurobiol Dis] 2026 Jan; Vol. 218, pp. 107225. <i>Date of Electronic Publication: </i>2025 Dec 17. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9500169 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1095-953X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209699961%22">09699961 </searchLink><i>NLM ISO Abbreviation: </i>Neurobiol Dis <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41419028 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.nbd.2025.107225 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 107225 Titles: – TitleFull: Diabetes increases SCO-spondin secretion but reduces Wnt5a interaction with ependymal cells, inducing ciliary stiffness and Frizzled-2 downregulation. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Cifuentes M – PersonEntity: Name: NameFull: Ramírez E – PersonEntity: Name: NameFull: Barahona MJ – PersonEntity: Name: NameFull: Martínez F – PersonEntity: Name: NameFull: de Lima I – PersonEntity: Name: NameFull: Ferrada L – PersonEntity: Name: NameFull: Bertinat R – PersonEntity: Name: NameFull: Ávila F – PersonEntity: Name: NameFull: Saldivia N – PersonEntity: Name: NameFull: Pérez-Martín M – PersonEntity: Name: NameFull: Oliver-Martin B – PersonEntity: Name: NameFull: Ciano-Petersen N – PersonEntity: Name: NameFull: Fernández-Arjona MDM – PersonEntity: Name: NameFull: Salazar K – PersonEntity: Name: NameFull: Nualart F IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: 2026 Jan Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1095-953X Numbering: – Type: volume Value: 218 Titles: – TitleFull: Neurobiology of disease Type: main |
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