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Industrialization of 3D hiPSC-cardiac microtissues for high-throughput cardiac safety and drug discovery screening.

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Title: Industrialization of 3D hiPSC-cardiac microtissues for high-throughput cardiac safety and drug discovery screening.
Authors: de Korte T; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands., Johnson BB; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden University Medical Center, Leiden, The Netherlands., Kosmidis G; Ncardia B.V., Leiden, The Netherlands., Samson-Couterie B; Ncardia B.V., Leiden, The Netherlands., Mol MPH; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands., van Helden RWJ; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands., Razaghi E; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands., François L; Ncardia B.V., Leiden, The Netherlands., Meraviglia V; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands., Yiangou L; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands., Kuipers T; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands., Mei H; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands., Bellin M; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden University Medical Center, Leiden, The Netherlands; Department of Biology, University of Padova, Padova, Italy., Braam SR; Ncardia B.V., Leiden, The Netherlands., Jain S; Ncardia B.V., Leiden, The Netherlands., Mummery CL; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden University Medical Center, Leiden, The Netherlands., Davis RP; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden University Medical Center, Leiden, The Netherlands. Electronic address: r.p.davis@lumc.nl.
Source: Trends in biotechnology [Trends Biotechnol] 2026 Apr; Vol. 44 (4), pp. 1100-1127. Date of Electronic Publication: 2025 Dec 18.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Publishers Country of Publication: England NLM ID: 8310903 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3096 (Electronic) Linking ISSN: 01677799 NLM ISO Abbreviation: Trends Biotechnol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Industrialization of 3D hiPSC-cardiac microtissues for high-throughput cardiac safety and drug discovery screening.
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  Data: <searchLink fieldCode="AU" term="%22de+Korte+T%22">de Korte T</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Johnson+BB%22">Johnson BB</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kosmidis+G%22">Kosmidis G</searchLink>; Ncardia B.V., Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Samson-Couterie+B%22">Samson-Couterie B</searchLink>; Ncardia B.V., Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Mol+MPH%22">Mol MPH</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Helden+RWJ%22">van Helden RWJ</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Razaghi+E%22">Razaghi E</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22François+L%22">François L</searchLink>; Ncardia B.V., Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Meraviglia+V%22">Meraviglia V</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Yiangou+L%22">Yiangou L</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kuipers+T%22">Kuipers T</searchLink>; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Mei+H%22">Mei H</searchLink>; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bellin+M%22">Bellin M</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden University Medical Center, Leiden, The Netherlands; Department of Biology, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Braam+SR%22">Braam SR</searchLink>; Ncardia B.V., Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Jain+S%22">Jain S</searchLink>; Ncardia B.V., Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Mummery+CL%22">Mummery CL</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Davis+RP%22">Davis RP</searchLink>; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden University Medical Center, Leiden, The Netherlands. Electronic address: r.p.davis@lumc.nl.
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  Data: <searchLink fieldCode="JN" term="%228310903%22">Trends in biotechnology</searchLink> [Trends Biotechnol] 2026 Apr; Vol. 44 (4), pp. 1100-1127. <i>Date of Electronic Publication: </i>2025 Dec 18.
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