Thrombopoietin increases susceptibility for EVI1 + KMT2A-MLLT3-driven AML expressing stem cell genes linked to poor outcome.
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| Title: | Thrombopoietin increases susceptibility for EVI1 + KMT2A-MLLT3-driven AML expressing stem cell genes linked to poor outcome. |
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| Authors: | Châtel-Soulet HÉ; University Children's Hospital & Department of Biomedicine, University of Basel, Basel, Switzerland., Juge S; University Children's Hospital & Department of Biomedicine, University of Basel, Basel, Switzerland., Pereira AL; Department of Medical Oncology and Haematology, University Hospital Zürich, Zürich, Switzerland., Seguin J; University Children's Hospital & Department of Biomedicine, University of Basel, Basel, Switzerland.; Swiss Institute of Bioinformatics (SIB), Basel, Switzerland., El Taher A; Swiss Institute of Bioinformatics (SIB), Basel, Switzerland.; Bioinformatics Core Facility, University of Basel, Basel, Switzerland., Valigi F; University Children's Hospital & Department of Biomedicine, University of Basel, Basel, Switzerland., Jevtic Z; University Children's Hospital & Department of Biomedicine, University of Basel, Basel, Switzerland., Sivalingam R; University Children's Hospital & Department of Biomedicine, University of Basel, Basel, Switzerland., Bagger FO; University Children's Hospital & Department of Biomedicine, University of Basel, Basel, Switzerland.; Center for Genomic Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Büschl P; Department of Medical Oncology and Haematology, University Hospital Zürich, Zürich, Switzerland., Almosailleakh M; University Children's Hospital & Department of Biomedicine, University of Basel, Basel, Switzerland.; Biotech Research and Innovation Center (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Tzankov A; Institute for Pathology, University of Basel, Basel, Switzerland., Tong W; Division of Haematology, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Kurokawa M; Department of Haematology and Oncology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan., Nombela Arrieta C; Department of Medical Oncology and Haematology, University Hospital Zürich, Zürich, Switzerland., Schwaller J; University Children's Hospital & Department of Biomedicine, University of Basel, Basel, Switzerland. J.Schwaller@unibas.ch. |
| Source: | Nature communications [Nat Commun] 2025 Dec 19; Vol. 17 (1), pp. 892. Date of Electronic Publication: 2025 Dec 19. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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