Barriers and facilitators to implementing clinical genome-wide sequencing: A scoping review of the global landscape.

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Title: Barriers and facilitators to implementing clinical genome-wide sequencing: A scoping review of the global landscape.
Authors: Lee W; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada., Yan J; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada., Fooks K; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada., Barwick M; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Dobrow M; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada., Friedman JM; Department of Medical Genetics, The University of British Columbia, Vancouver, BC, Canada., Marshall CR; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada; Division of Genome Diagnostics, Department of Pediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada., Hayeems RZ; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada. Electronic address: robin.hayeems@sickkids.ca.
Source: Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2026 Mar; Vol. 28 (3), pp. 101665. Date of Electronic Publication: 2025 Dec 17.
Publication Type: Journal Article; Scoping Review; Review
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9815831 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0366 (Electronic) Linking ISSN: 10983600 NLM ISO Abbreviation: Genet Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Lee+W%22">Lee W</searchLink>; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Yan+J%22">Yan J</searchLink>; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Fooks+K%22">Fooks K</searchLink>; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Barwick+M%22">Barwick M</searchLink>; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Dobrow+M%22">Dobrow M</searchLink>; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Friedman+JM%22">Friedman JM</searchLink>; Department of Medical Genetics, The University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Marshall+CR%22">Marshall CR</searchLink>; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada; Division of Genome Diagnostics, Department of Pediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Hayeems+RZ%22">Hayeems RZ</searchLink>; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada. Electronic address: robin.hayeems@sickkids.ca.
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        Value: 10.1016/j.gim.2025.101665
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        Text: English
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              Text: 2026 Mar
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