Pumpkin seed oil improves hepatotoxicity in rats through inhibition of CYP2E1 and activation of Nrf2 signaling pathways.
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| Title: | Pumpkin seed oil improves hepatotoxicity in rats through inhibition of CYP2E1 and activation of Nrf2 signaling pathways. |
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| Authors: | Esmail NW; Department of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, Egypt., El-Sheikh SM; Department of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, Egypt., Korany RMS; Pathology Department, Faculty of Veterinary Medicine, Cairo University, Egypt., Hassan AA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, El Saleheya El Gadida University, El Saleheya El Gadida, 44813, Egypt., Baraka SM; Chemistry of Natural Compounds Department, National Research Centre, Giza 12622, Egypt., Alharbi HM; Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia. Electronic address: Hmalharbi@pnu.edu.sa., Ismail AK; Department of Forensic Medicine and Toxicology, College of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt; Department of clinical pharmacology and forensic medicine and toxicology, College of Medicine, Taif University, Saudi Arabia., Mansour DA; Department of Biochemistry and Chemistry of Nutrition, Faculty of Veterinary Medicine, University of Sadat City, Egypt., Mahboub HH; Department of Aquatic Animal Medicine, Faculty of Veterinary Medicine, Zagazig University, P.O. Box 44511, Zagazig, Sharkia, Egypt. Electronic address: hhhmb@yahoo.com., Fahmy EM; Department of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, Egypt. |
| Source: | Tissue & cell [Tissue Cell] 2026 Apr; Vol. 99, pp. 103286. Date of Electronic Publication: 2025 Dec 17. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 0214745 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3072 (Electronic) Linking ISSN: 00408166 NLM ISO Abbreviation: Tissue Cell Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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