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Islet amyloid disrupts MHC class II antigen presentation and delays autoimmune diabetes in NOD mice.

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Title: Islet amyloid disrupts MHC class II antigen presentation and delays autoimmune diabetes in NOD mice.
Authors: Denroche HC; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Surgery, University of British Columbia, Vancouver, BC, Canada., Ng V; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Surgery, University of British Columbia, Vancouver, BC, Canada.; Integrated Nanotherapeutics Inc., Burnaby, BC, Canada., Velghe J; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada., Suen I; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada., Stanley L; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Surgery, University of British Columbia, Vancouver, BC, Canada., Nackiewicz D; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada., Komba M; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Surgery, University of British Columbia, Vancouver, BC, Canada., Dai DL; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Surgery, University of British Columbia, Vancouver, BC, Canada., Soukhatcheva G; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Surgery, University of British Columbia, Vancouver, BC, Canada., Chen S; Integrated Nanotherapeutics Inc., Burnaby, BC, Canada., Verchere CB; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Surgery, University of British Columbia, Vancouver, BC, Canada. bverchere@bcchr.ca.; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada. bverchere@bcchr.ca.; Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC, Canada. bverchere@bcchr.ca.
Source: Diabetologia [Diabetologia] 2026 Apr; Vol. 69 (4), pp. 987-999. Date of Electronic Publication: 2025 Dec 22.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE
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  Data: Islet amyloid disrupts MHC class II antigen presentation and delays autoimmune diabetes in NOD mice.
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  Data: <searchLink fieldCode="AU" term="%22Denroche+HC%22">Denroche HC</searchLink>; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Surgery, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Ng+V%22">Ng V</searchLink>; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Surgery, University of British Columbia, Vancouver, BC, Canada.; Integrated Nanotherapeutics Inc., Burnaby, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Velghe+J%22">Velghe J</searchLink>; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Suen+I%22">Suen I</searchLink>; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Stanley+L%22">Stanley L</searchLink>; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Surgery, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Nackiewicz+D%22">Nackiewicz D</searchLink>; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Komba+M%22">Komba M</searchLink>; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Surgery, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Dai+DL%22">Dai DL</searchLink>; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Surgery, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Soukhatcheva+G%22">Soukhatcheva G</searchLink>; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Surgery, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Chen+S%22">Chen S</searchLink>; Integrated Nanotherapeutics Inc., Burnaby, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Verchere+CB%22">Verchere CB</searchLink>; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Surgery, University of British Columbia, Vancouver, BC, Canada. bverchere@bcchr.ca.; Canucks for Kids Fund Childhood Diabetes Laboratories, BC Children's Hospital Research Institute, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada. bverchere@bcchr.ca.; Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC, Canada. bverchere@bcchr.ca.
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  Data: <searchLink fieldCode="JN" term="%220006777%22">Diabetologia</searchLink> [Diabetologia] 2026 Apr; Vol. 69 (4), pp. 987-999. <i>Date of Electronic Publication: </i>2025 Dec 22.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0006777 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0428 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220012186X%22">0012186X </searchLink><i>NLM ISO Abbreviation: </i>Diabetologia <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00125-025-06622-0
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              Text: 2026 Apr
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