Multi-omics analysis identifies SMPD1 as a key contributor in sphingolipid pathway for Type 2 diabetes pathogenesis.

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Title: Multi-omics analysis identifies SMPD1 as a key contributor in sphingolipid pathway for Type 2 diabetes pathogenesis.
Authors: Park A; Department of Health Sciences and Technology, Gachon Advanced Institute for Health Sciences and Technology (GAIHST), Gachon University, Incheon, Republic of Korea., Kang BE; Department of Physiology, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea., Jin EJ; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea., Kim HJ; Department of Physiology, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea., Lee CW; Department of Molecular Cell Biology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea., Suh JM; Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea., Ryu D; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea. dryu@gist.ac.kr., Nam S; Department of Health Sciences and Technology, Gachon Advanced Institute for Health Sciences and Technology (GAIHST), Gachon University, Incheon, Republic of Korea. nams@gachon.ac.kr.; Department of Genome Medicine and Science, Gachon Institute of Genome Medicine and Science, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea. nams@gachon.ac.kr.
Source: Genes & genomics [Genes Genomics] 2026 Mar; Vol. 48 (3), pp. 369-381. Date of Electronic Publication: 2025 Dec 22.
Publication Type: Journal Article
Journal Info: Publisher: The Korean Society of Genetics Country of Publication: Korea (South) NLM ID: 101481027 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2092-9293 (Electronic) Linking ISSN: 19769571 NLM ISO Abbreviation: Genes Genomics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Multi-omics analysis identifies SMPD1 as a key contributor in sphingolipid pathway for Type 2 diabetes pathogenesis.
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  Data: <searchLink fieldCode="AU" term="%22Park+A%22">Park A</searchLink>; Department of Health Sciences and Technology, Gachon Advanced Institute for Health Sciences and Technology (GAIHST), Gachon University, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kang+BE%22">Kang BE</searchLink>; Department of Physiology, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jin+EJ%22">Jin EJ</searchLink>; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+HJ%22">Kim HJ</searchLink>; Department of Physiology, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+CW%22">Lee CW</searchLink>; Department of Molecular Cell Biology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Suh+JM%22">Suh JM</searchLink>; Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ryu+D%22">Ryu D</searchLink>; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea. dryu@gist.ac.kr.<br /><searchLink fieldCode="AU" term="%22Nam+S%22">Nam S</searchLink>; Department of Health Sciences and Technology, Gachon Advanced Institute for Health Sciences and Technology (GAIHST), Gachon University, Incheon, Republic of Korea. nams@gachon.ac.kr.; Department of Genome Medicine and Science, Gachon Institute of Genome Medicine and Science, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea. nams@gachon.ac.kr.
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  Data: <searchLink fieldCode="JN" term="%22101481027%22">Genes & genomics</searchLink> [Genes Genomics] 2026 Mar; Vol. 48 (3), pp. 369-381. <i>Date of Electronic Publication: </i>2025 Dec 22.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22The+Korean+Society+of+Genetics%22">The Korean Society of Genetics </searchLink><i>Country of Publication: </i>Korea (South) <i>NLM ID: </i>101481027 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2092-9293 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219769571%22">19769571 </searchLink><i>NLM ISO Abbreviation: </i>Genes Genomics <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s13258-025-01727-7
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        Text: English
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      – TitleFull: Multi-omics analysis identifies SMPD1 as a key contributor in sphingolipid pathway for Type 2 diabetes pathogenesis.
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              Text: 2026 Mar
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              Y: 2026
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