Multi-omics analysis identifies SMPD1 as a key contributor in sphingolipid pathway for Type 2 diabetes pathogenesis.

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Title: Multi-omics analysis identifies SMPD1 as a key contributor in sphingolipid pathway for Type 2 diabetes pathogenesis.
Authors: Park A; Department of Health Sciences and Technology, Gachon Advanced Institute for Health Sciences and Technology (GAIHST), Gachon University, Incheon, Republic of Korea., Kang BE; Department of Physiology, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea., Jin EJ; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea., Kim HJ; Department of Physiology, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea., Lee CW; Department of Molecular Cell Biology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea., Suh JM; Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea., Ryu D; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea. dryu@gist.ac.kr., Nam S; Department of Health Sciences and Technology, Gachon Advanced Institute for Health Sciences and Technology (GAIHST), Gachon University, Incheon, Republic of Korea. nams@gachon.ac.kr.; Department of Genome Medicine and Science, Gachon Institute of Genome Medicine and Science, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea. nams@gachon.ac.kr.
Source: Genes & genomics [Genes Genomics] 2026 Mar; Vol. 48 (3), pp. 369-381. Date of Electronic Publication: 2025 Dec 22.
Publication Type: Journal Article
Journal Info: Publisher: The Korean Society of Genetics Country of Publication: Korea (South) NLM ID: 101481027 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2092-9293 (Electronic) Linking ISSN: 19769571 NLM ISO Abbreviation: Genes Genomics Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2092-9293
DOI:10.1007/s13258-025-01727-7