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Antibiotic De-Escalation in Adults Hospitalized for Community-Onset Sepsis.

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Title: Antibiotic De-Escalation in Adults Hospitalized for Community-Onset Sepsis.
Authors: Gupta AB; Medicine Service, VA Ann Arbor Healthcare System, Ann Arbor, Michigan.; Department of Internal Medicine, University of Michigan, Ann Arbor., Heath M; Department of Internal Medicine, University of Michigan, Ann Arbor., Walzl E; Department of Internal Medicine, University of Michigan, Ann Arbor., Ratz D; VA Center for Clinical Management Research, Ann Arbor, Michigan., Munroe E; Department of Internal Medicine, University of Michigan, Ann Arbor., Vaughn VM; Department of Internal Medicine, University of Michigan, Ann Arbor.; Department of Internal Medicine, University of Utah, Salt Lake City.; Division of Health System Innovation & Research, Department of Population Health Sciences, University of Utah, Salt Lake City., Horowitz JK; Department of Internal Medicine, University of Michigan, Ann Arbor., Czilok T; Department of Internal Medicine, University of Michigan, Ann Arbor., Petty LA; Department of Internal Medicine, University of Michigan, Ann Arbor., Gandhi TN; Department of Internal Medicine, University of Michigan, Ann Arbor., Taylor SP; Department of Internal Medicine, University of Michigan, Ann Arbor., McLaughlin ES; Department of Internal Medicine, University of Michigan, Ann Arbor., Posa P; Department of Internal Medicine, University of Michigan, Ann Arbor., Malani AN; Section of Infectious Diseases, Trinity Health Michigan, Ann Arbor., Hsaiky L; Department of Pharmacy, Corewell Healthcare System, Dearborn, Michigan., Flanders SA; Department of Internal Medicine, University of Michigan, Ann Arbor., Prescott HC; Medicine Service, VA Ann Arbor Healthcare System, Ann Arbor, Michigan.; Department of Internal Medicine, University of Michigan, Ann Arbor.; VA Center for Clinical Management Research, Ann Arbor, Michigan.
Source: JAMA internal medicine [JAMA Intern Med] 2026 Feb 01; Vol. 186 (2), pp. 192-202.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589534 Publication Model: Print Cited Medium: Internet ISSN: 2168-6114 (Electronic) Linking ISSN: 21686106 NLM ISO Abbreviation: JAMA Intern Med Subsets: MEDLINE
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  Data: Antibiotic De-Escalation in Adults Hospitalized for Community-Onset Sepsis.
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  Data: <searchLink fieldCode="AU" term="%22Gupta+AB%22">Gupta AB</searchLink>; Medicine Service, VA Ann Arbor Healthcare System, Ann Arbor, Michigan.; Department of Internal Medicine, University of Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22Heath+M%22">Heath M</searchLink>; Department of Internal Medicine, University of Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22Walzl+E%22">Walzl E</searchLink>; Department of Internal Medicine, University of Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22Ratz+D%22">Ratz D</searchLink>; VA Center for Clinical Management Research, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Munroe+E%22">Munroe E</searchLink>; Department of Internal Medicine, University of Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22Vaughn+VM%22">Vaughn VM</searchLink>; Department of Internal Medicine, University of Michigan, Ann Arbor.; Department of Internal Medicine, University of Utah, Salt Lake City.; Division of Health System Innovation & Research, Department of Population Health Sciences, University of Utah, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Horowitz+JK%22">Horowitz JK</searchLink>; Department of Internal Medicine, University of Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22Czilok+T%22">Czilok T</searchLink>; Department of Internal Medicine, University of Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22Petty+LA%22">Petty LA</searchLink>; Department of Internal Medicine, University of Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22Gandhi+TN%22">Gandhi TN</searchLink>; Department of Internal Medicine, University of Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22Taylor+SP%22">Taylor SP</searchLink>; Department of Internal Medicine, University of Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22McLaughlin+ES%22">McLaughlin ES</searchLink>; Department of Internal Medicine, University of Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22Posa+P%22">Posa P</searchLink>; Department of Internal Medicine, University of Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22Malani+AN%22">Malani AN</searchLink>; Section of Infectious Diseases, Trinity Health Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22Hsaiky+L%22">Hsaiky L</searchLink>; Department of Pharmacy, Corewell Healthcare System, Dearborn, Michigan.<br /><searchLink fieldCode="AU" term="%22Flanders+SA%22">Flanders SA</searchLink>; Department of Internal Medicine, University of Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22Prescott+HC%22">Prescott HC</searchLink>; Medicine Service, VA Ann Arbor Healthcare System, Ann Arbor, Michigan.; Department of Internal Medicine, University of Michigan, Ann Arbor.; VA Center for Clinical Management Research, Ann Arbor, Michigan.
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  Data: <searchLink fieldCode="JN" term="%22101589534%22">JAMA internal medicine</searchLink> [JAMA Intern Med] 2026 Feb 01; Vol. 186 (2), pp. 192-202.
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