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CRESTONE: A Phase II Study of the Efficacy and Safety of the HER3 Monoclonal Antibody, Seribantumab, in Solid Tumors With Neuregulin-1 (NRG1) Fusions.

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Title: CRESTONE: A Phase II Study of the Efficacy and Safety of the HER3 Monoclonal Antibody, Seribantumab, in Solid Tumors With Neuregulin-1 (NRG1) Fusions.
Authors: Patil T; University of Colorado Cancer Center, Aurora, CO., Lin JJ; Massachusetts General Hospital, Boston, MA., Cheema PK; William Osler Health System, Calgary, Canada., Carrizosa DR; Levine Cancer Institute/Atrium Health, Charlotte, NC., Burkard ME; University of Iowa Health Care Holden Comprehensive Cancer Center, Iowa City, IA., Elamin YY; The University of Texas MD Anderson Cancer Center, Houston, TX., Desai J; Peter MacCallum Cancer Centre, Melbourne, Australia., Patel JD; Northwestern University, Chicago, IL., Nagasaka M; Chao Family Comprehensive Cancer Center, University of California Irvine, Orange, CA., Reckamp KL; Cedars-Sinai Medical Center, Los Angeles, CA., Waqar SN; Washington University School of Medicine, St Louis, MO., Bauman JR; Fox Chase Cancer Center, Philadelphia, PA., Schram AM; Memorial Sloan Kettering Cancer Center, New York, NY., Gadgeel SM; Henry Ford Cancer Institute/Henry Ford Health System, Detroit, MI., Ma PC; Penn State Cancer Institute, Penn State University, Hershey, PA., Konduri K; Baylor Charles A. Sammons Cancer Center, Texas Oncology PA, Dallas, TX., Nguyen D; City of Hope, Huntington Beach, CA.; City of Hope, Irvine, CA., Misleh J; Medical Oncology Hematology Consultants, Newark, DE., Bleeker J; Sanford USD Medical Center, Sioux Falls, SD., Weiss M; ThedaCare Cancer Center, Appleton, WI., Thavaneswaran S; The Kinghorn Cancer Centre, St Vincent's Hospital, Sydney, Australia., Haura EB; H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL., Deegan M; Elevation Oncology, Inc., Boston, MA., Kaufman J; Elevation Oncology, Inc., Boston, MA., Srivastava J; Elevation Oncology, Inc., Boston, MA., Jansen VM; Elevation Oncology, Inc., Boston, MA., Liu SV; Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC.
Source: JCO precision oncology [JCO Precis Oncol] 2025 Aug; Vol. 9, pp. e2500221. Date of Electronic Publication: 2025 Dec 22.
Publication Type: Journal Article; Clinical Trial, Phase II; Multicenter Study
Journal Info: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 101705370 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2473-4284 (Electronic) Linking ISSN: 24734284 NLM ISO Abbreviation: JCO Precis Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CRESTONE: A Phase II Study of the Efficacy and Safety of the HER3 Monoclonal Antibody, Seribantumab, in Solid Tumors With Neuregulin-1 (NRG1) Fusions.
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  Data: <searchLink fieldCode="AU" term="%22Patil+T%22">Patil T</searchLink>; University of Colorado Cancer Center, Aurora, CO.<br /><searchLink fieldCode="AU" term="%22Lin+JJ%22">Lin JJ</searchLink>; Massachusetts General Hospital, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Cheema+PK%22">Cheema PK</searchLink>; William Osler Health System, Calgary, Canada.<br /><searchLink fieldCode="AU" term="%22Carrizosa+DR%22">Carrizosa DR</searchLink>; Levine Cancer Institute/Atrium Health, Charlotte, NC.<br /><searchLink fieldCode="AU" term="%22Burkard+ME%22">Burkard ME</searchLink>; University of Iowa Health Care Holden Comprehensive Cancer Center, Iowa City, IA.<br /><searchLink fieldCode="AU" term="%22Elamin+YY%22">Elamin YY</searchLink>; The University of Texas MD Anderson Cancer Center, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Desai+J%22">Desai J</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Patel+JD%22">Patel JD</searchLink>; Northwestern University, Chicago, IL.<br /><searchLink fieldCode="AU" term="%22Nagasaka+M%22">Nagasaka M</searchLink>; Chao Family Comprehensive Cancer Center, University of California Irvine, Orange, CA.<br /><searchLink fieldCode="AU" term="%22Reckamp+KL%22">Reckamp KL</searchLink>; Cedars-Sinai Medical Center, Los Angeles, CA.<br /><searchLink fieldCode="AU" term="%22Waqar+SN%22">Waqar SN</searchLink>; Washington University School of Medicine, St Louis, MO.<br /><searchLink fieldCode="AU" term="%22Bauman+JR%22">Bauman JR</searchLink>; Fox Chase Cancer Center, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Schram+AM%22">Schram AM</searchLink>; Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Gadgeel+SM%22">Gadgeel SM</searchLink>; Henry Ford Cancer Institute/Henry Ford Health System, Detroit, MI.<br /><searchLink fieldCode="AU" term="%22Ma+PC%22">Ma PC</searchLink>; Penn State Cancer Institute, Penn State University, Hershey, PA.<br /><searchLink fieldCode="AU" term="%22Konduri+K%22">Konduri K</searchLink>; Baylor Charles A. Sammons Cancer Center, Texas Oncology PA, Dallas, TX.<br /><searchLink fieldCode="AU" term="%22Nguyen+D%22">Nguyen D</searchLink>; City of Hope, Huntington Beach, CA.; City of Hope, Irvine, CA.<br /><searchLink fieldCode="AU" term="%22Misleh+J%22">Misleh J</searchLink>; Medical Oncology Hematology Consultants, Newark, DE.<br /><searchLink fieldCode="AU" term="%22Bleeker+J%22">Bleeker J</searchLink>; Sanford USD Medical Center, Sioux Falls, SD.<br /><searchLink fieldCode="AU" term="%22Weiss+M%22">Weiss M</searchLink>; ThedaCare Cancer Center, Appleton, WI.<br /><searchLink fieldCode="AU" term="%22Thavaneswaran+S%22">Thavaneswaran S</searchLink>; The Kinghorn Cancer Centre, St Vincent's Hospital, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Haura+EB%22">Haura EB</searchLink>; H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL.<br /><searchLink fieldCode="AU" term="%22Deegan+M%22">Deegan M</searchLink>; Elevation Oncology, Inc., Boston, MA.<br /><searchLink fieldCode="AU" term="%22Kaufman+J%22">Kaufman J</searchLink>; Elevation Oncology, Inc., Boston, MA.<br /><searchLink fieldCode="AU" term="%22Srivastava+J%22">Srivastava J</searchLink>; Elevation Oncology, Inc., Boston, MA.<br /><searchLink fieldCode="AU" term="%22Jansen+VM%22">Jansen VM</searchLink>; Elevation Oncology, Inc., Boston, MA.<br /><searchLink fieldCode="AU" term="%22Liu+SV%22">Liu SV</searchLink>; Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC.
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  Data: <searchLink fieldCode="JN" term="%22101705370%22">JCO precision oncology</searchLink> [JCO Precis Oncol] 2025 Aug; Vol. 9, pp. e2500221. <i>Date of Electronic Publication: </i>2025 Dec 22.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+of+Clinical+Oncology%22">American Society of Clinical Oncology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101705370 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2473-4284 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224734284%22">24734284 </searchLink><i>NLM ISO Abbreviation: </i>JCO Precis Oncol <i>Subsets: </i>MEDLINE
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