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ADAM17-dependent Autocrine and Paracrine Signaling Promotes Pancreatic Premalignant Progression.

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Title: ADAM17-dependent Autocrine and Paracrine Signaling Promotes Pancreatic Premalignant Progression.
Authors: Wen HJ; Department of Surgery, Henry Ford Health System, Detroit, Michigan., Davis ET; Department of Surgery, Henry Ford Health System, Detroit, Michigan., Moore JS; Department of Surgery, Henry Ford Health System, Detroit, Michigan., Brender SM; Department of Surgery, Henry Ford Health System, Detroit, Michigan., Benitz S; Department of Surgery, Henry Ford Health System, Detroit, Michigan., Wombwell AM; Department of Surgery, Henry Ford Health System, Detroit, Michigan., Loveless IM; Department of Public Health Sciences, Center for Bioinformatics, Henry Ford Health, Detroit, Michigan; Department of Computational Mathematics, Science, and Engineering, Medical Imaging and Data Integration Lab, Michigan State University, East Lansing, Michigan., Long DW; Department of Surgery, Henry Ford Health System, Detroit, Michigan., Salas-Escabillas DJ; Department of Surgery, Henry Ford Health System, Detroit, Michigan., Lee J; Department of Surgery, Henry Ford Health System, Detroit, Michigan., Devorkin BS; Department of Surgery, Henry Ford Health System, Detroit, Michigan., McQuithey H; Department of Surgery, Henry Ford Health System, Detroit, Michigan., Steele NG; Division of Digestive Diseases, Department of Internal medicine, College of Medicine, University of Cincinnati, Cincinnati, Ohio., Hurt E; Tumor Targeted Delivery Bioscience, Oncology R&D, AstraZeneca, Gaithersburg, Maryland., Crawford HC; Department of Surgery, Henry Ford Health System, Detroit, Michigan; Department of Pharmacology and Toxicology, Michigan State University, Lansing, Michigan. Electronic address: hcrawfo1@hfhs.org.
Source: Cellular and molecular gastroenterology and hepatology [Cell Mol Gastroenterol Hepatol] 2026; Vol. 20 (4), pp. 101711. Date of Electronic Publication: 2025 Dec 20.
Publication Type: Journal Article
Journal Info: Publisher: American Gastroenterological Association Country of Publication: United States NLM ID: 101648302 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-345X (Electronic) Linking ISSN: 2352345X NLM ISO Abbreviation: Cell Mol Gastroenterol Hepatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: ADAM17-dependent Autocrine and Paracrine Signaling Promotes Pancreatic Premalignant Progression.
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  Data: <searchLink fieldCode="AU" term="%22Wen+HJ%22">Wen HJ</searchLink>; Department of Surgery, Henry Ford Health System, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Davis+ET%22">Davis ET</searchLink>; Department of Surgery, Henry Ford Health System, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Moore+JS%22">Moore JS</searchLink>; Department of Surgery, Henry Ford Health System, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Brender+SM%22">Brender SM</searchLink>; Department of Surgery, Henry Ford Health System, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Benitz+S%22">Benitz S</searchLink>; Department of Surgery, Henry Ford Health System, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Wombwell+AM%22">Wombwell AM</searchLink>; Department of Surgery, Henry Ford Health System, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Loveless+IM%22">Loveless IM</searchLink>; Department of Public Health Sciences, Center for Bioinformatics, Henry Ford Health, Detroit, Michigan; Department of Computational Mathematics, Science, and Engineering, Medical Imaging and Data Integration Lab, Michigan State University, East Lansing, Michigan.<br /><searchLink fieldCode="AU" term="%22Long+DW%22">Long DW</searchLink>; Department of Surgery, Henry Ford Health System, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Salas-Escabillas+DJ%22">Salas-Escabillas DJ</searchLink>; Department of Surgery, Henry Ford Health System, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Department of Surgery, Henry Ford Health System, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Devorkin+BS%22">Devorkin BS</searchLink>; Department of Surgery, Henry Ford Health System, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22McQuithey+H%22">McQuithey H</searchLink>; Department of Surgery, Henry Ford Health System, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Steele+NG%22">Steele NG</searchLink>; Division of Digestive Diseases, Department of Internal medicine, College of Medicine, University of Cincinnati, Cincinnati, Ohio.<br /><searchLink fieldCode="AU" term="%22Hurt+E%22">Hurt E</searchLink>; Tumor Targeted Delivery Bioscience, Oncology R&D, AstraZeneca, Gaithersburg, Maryland.<br /><searchLink fieldCode="AU" term="%22Crawford+HC%22">Crawford HC</searchLink>; Department of Surgery, Henry Ford Health System, Detroit, Michigan; Department of Pharmacology and Toxicology, Michigan State University, Lansing, Michigan. Electronic address: hcrawfo1@hfhs.org.
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  Data: <searchLink fieldCode="JN" term="%22101648302%22">Cellular and molecular gastroenterology and hepatology</searchLink> [Cell Mol Gastroenterol Hepatol] 2026; Vol. 20 (4), pp. 101711. <i>Date of Electronic Publication: </i>2025 Dec 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Gastroenterological+Association%22">American Gastroenterological Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101648302 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2352-345X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222352345X%22">2352345X </searchLink><i>NLM ISO Abbreviation: </i>Cell Mol Gastroenterol Hepatol <i>Subsets: </i>MEDLINE
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