C/EBPβ-induced alternative splicing of RCAN1 generates a potent TCR-T target in mesenchymal glioblastoma.
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| Title: | C/EBPβ-induced alternative splicing of RCAN1 generates a potent TCR-T target in mesenchymal glioblastoma. |
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| Authors: | Xiong Z; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Kong Q; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Chagantipati B; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Stepniak A; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Jaswal AP; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Radiology, Weill Cornell Medical College, New York, NY, USA., Sneiderman CT; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Han Y; Department of Nephrology, Xiangya Hospital, Central South University, Changsha, Hunan, China., Jackson SA; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA., Raphael RA; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Institute for Drug Research (IDR), School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel., Zhang W; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China., Li M; The Second School of Clinical Medicine, Anhui Medical University, Hefei, Anhui, China., Chao Y; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Qin B; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; National Center for International Research in Cell and Gene Therapy, Sino-British Research Center for Molecular Oncology, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China., Dulkadir Z; Department of Molecular Microbiology and Immunology, University of Texas at San Antonio, San Antonio, TX, USA., Schwegman L; Department of Molecular Microbiology and Immunology, University of Texas at San Antonio, San Antonio, TX, USA., Zhang Y; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China., Kuminkoski C; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Mahlke MA; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Nath P; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Hu B; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Zinn PO; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Mantica M; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA., Agnihotri S; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Nechemia-Arbely Y; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Pollack IF; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Rigatti LH; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Division of Laboratory Animal Resources, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Forsthuber TG; Department of Molecular Microbiology and Immunology, University of Texas at San Antonio, San Antonio, TX, USA., Li X; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.; Hunan International Scientific and Technological Cooperation Base of Brain Tumor Research, Xiangya Hospital, Central South University, Changsha, China., Raphael I; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA. Itay.Raphael@mail.huji.ac.il.; Institute for Drug Research (IDR), School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel. Itay.Raphael@mail.huji.ac.il., Kohanbash G; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA. gary.kohanbash2@chp.edu.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA. gary.kohanbash2@chp.edu.; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA. gary.kohanbash2@chp.edu. |
| Source: | Cellular & molecular immunology [Cell Mol Immunol] 2026 Jan; Vol. 23 (1), pp. 94-113. Date of Electronic Publication: 2025 Dec 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Chinese Society of Immunology Country of Publication: China NLM ID: 101242872 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2042-0226 (Electronic) Linking ISSN: 16727681 NLM ISO Abbreviation: Cell Mol Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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