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Challenges Facing Evidence-Synthesis and Clinical Practice Guidelines, and Their Solutions: Restoring Balance Through Core GRADE.

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Title: Challenges Facing Evidence-Synthesis and Clinical Practice Guidelines, and Their Solutions: Restoring Balance Through Core GRADE.
Authors: Guyatt G; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.; MAGIC Evidence Ecosystem Foundation, Oslo, Norway., Colunga-Lozano LE; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.; Department of Clinical Medicine, Health Science Center, Universidad De Guadalajara, Guadalajara, Jalisco, México.; Department of Critical Care, Hospital Civil de Guadalajara, Dr. Juan I Menchaca, Guadalajara, Jalisco, México.
Source: Journal of evidence-based medicine [J Evid Based Med] 2025 Dec; Vol. 18 (4), pp. e70098. Date of Electronic Publication: 2025 Dec 23.
Publication Type: Editorial
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101497477 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1756-5391 (Electronic) Linking ISSN: 17565391 NLM ISO Abbreviation: J Evid Based Med Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Guyatt+G%22">Guyatt G</searchLink>; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.; MAGIC Evidence Ecosystem Foundation, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Colunga-Lozano+LE%22">Colunga-Lozano LE</searchLink>; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.; Department of Clinical Medicine, Health Science Center, Universidad De Guadalajara, Guadalajara, Jalisco, México.; Department of Critical Care, Hospital Civil de Guadalajara, Dr. Juan I Menchaca, Guadalajara, Jalisco, México.
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        Value: 10.1111/jebm.70098
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      – TitleFull: Challenges Facing Evidence-Synthesis and Clinical Practice Guidelines, and Their Solutions: Restoring Balance Through Core GRADE.
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              Text: 2025 Dec
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              Y: 2025
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