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A synergistic nanoformulation of propolis and chlorhexidine against Acanthamoeba: encapsulation efficiency, release kinetics, and safety evaluation.

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Title: A synergistic nanoformulation of propolis and chlorhexidine against Acanthamoeba: encapsulation efficiency, release kinetics, and safety evaluation.
Authors: Marimuthu N; Department of Biotechnology, Aarupadai Veedu Institute of Technology, Vinayaka Mission's Research Foundation (DU), Chennai, Tamil Nadu, India., Chimplee S; General Education Department, School of Languages and General Education, Walailak University, Nakhon Si Thammarat, Thailand., Saravanabhavan SS; Department of Biotechnology, Aarupadai Veedu Institute of Technology, Vinayaka Mission's Research Foundation (DU), Chennai, Tamil Nadu, India., Labana RV; The Graduate School, University of Santo Tomas, Manila, National Capital Region, Philippines.; Center for Health Sciences, Research Institute for Science and Technology, and Department of Biology, College of Science, Polytechnic University of the Philippines, Manila, National Capital Region, Philippines., Sowri VVR; Department of Biotechnology, Aarupadai Veedu Institute of Technology, Vinayaka Mission's Research Foundation (DU), Chennai, Tamil Nadu, India., Jimoh TO; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, United States of America., Lee WC; Department of Parasitology, Universiti Malaya, Kuala Lumpur, Malaysia.; A*STAR Infectious Diseases Labs, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Hailu T; Department of Medical Laboratory Sciences, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia., Brandon-Mong GJ; Biodiversity Research Center, Academia Sinica, Taipei, Taiwan., Boonroumkaew P; Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand., Jaroonwitchawan T; Futuristic Science Reach Center, School of Science, and Research Excellence Center for Innovation and Health Products (RECIHP), Walailak University, Nakhon Si Thammarat, Thailand., Mitsuwan W; Akkhraratchakumari Veterinary College, Walailak University, Nakhon Si Thammarat, Thailand., Lim CL; Division of Applied Biomedical Science and Biotechnology, School of Health Sciences, IMU University, Kuala Lumpur, Malaysia., Koh RY; Division of Applied Biomedical Science and Biotechnology, School of Health Sciences, IMU University, Kuala Lumpur, Malaysia., Chandramathi S; Department of Medical Microbiology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia., Nawaz M; Department of Nano-Medicine Research, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia., Pereira ML; CICECO-Aveiro Institute of Materials and Department of Medical Sciences, University of Aveiro, Aveiro, Portugal., Wiart C; Institute of Tropical Biology and Conservation, University Malaysia Sabah, Kota Kinabalu, Malaysia., Oliveira SMR; CICECO-Aveiro Institute of Materials, University of Aveiro, Aveiro, Portugal., Nissapatorn V; Futuristic Science Reach Center, School of Science, and World Union for Herbal Drug Discovery (WUHeDD), Walailak University, Nakhon Si Thammarat, Thailand.
Source: PeerJ [PeerJ] 2025 Dec 19; Vol. 13, pp. e20493. Date of Electronic Publication: 2025 Dec 19 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: PeerJ Inc Country of Publication: United States NLM ID: 101603425 Publication Model: eCollection Cited Medium: Internet ISSN: 2167-8359 (Electronic) Linking ISSN: 21678359 NLM ISO Abbreviation: PeerJ Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Marimuthu+N%22">Marimuthu N</searchLink>; Department of Biotechnology, Aarupadai Veedu Institute of Technology, Vinayaka Mission's Research Foundation (DU), Chennai, Tamil Nadu, India.<br /><searchLink fieldCode="AU" term="%22Chimplee+S%22">Chimplee S</searchLink>; General Education Department, School of Languages and General Education, Walailak University, Nakhon Si Thammarat, Thailand.<br /><searchLink fieldCode="AU" term="%22Saravanabhavan+SS%22">Saravanabhavan SS</searchLink>; Department of Biotechnology, Aarupadai Veedu Institute of Technology, Vinayaka Mission's Research Foundation (DU), Chennai, Tamil Nadu, India.<br /><searchLink fieldCode="AU" term="%22Labana+RV%22">Labana RV</searchLink>; The Graduate School, University of Santo Tomas, Manila, National Capital Region, Philippines.; Center for Health Sciences, Research Institute for Science and Technology, and Department of Biology, College of Science, Polytechnic University of the Philippines, Manila, National Capital Region, Philippines.<br /><searchLink fieldCode="AU" term="%22Sowri+VVR%22">Sowri VVR</searchLink>; Department of Biotechnology, Aarupadai Veedu Institute of Technology, Vinayaka Mission's Research Foundation (DU), Chennai, Tamil Nadu, India.<br /><searchLink fieldCode="AU" term="%22Jimoh+TO%22">Jimoh TO</searchLink>; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22Lee+WC%22">Lee WC</searchLink>; Department of Parasitology, Universiti Malaya, Kuala Lumpur, Malaysia.; A*STAR Infectious Diseases Labs, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Hailu+T%22">Hailu T</searchLink>; Department of Medical Laboratory Sciences, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.<br /><searchLink fieldCode="AU" term="%22Brandon-Mong+GJ%22">Brandon-Mong GJ</searchLink>; Biodiversity Research Center, Academia Sinica, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Boonroumkaew+P%22">Boonroumkaew P</searchLink>; Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.<br /><searchLink fieldCode="AU" term="%22Jaroonwitchawan+T%22">Jaroonwitchawan T</searchLink>; Futuristic Science Reach Center, School of Science, and Research Excellence Center for Innovation and Health Products (RECIHP), Walailak University, Nakhon Si Thammarat, Thailand.<br /><searchLink fieldCode="AU" term="%22Mitsuwan+W%22">Mitsuwan W</searchLink>; Akkhraratchakumari Veterinary College, Walailak University, Nakhon Si Thammarat, Thailand.<br /><searchLink fieldCode="AU" term="%22Lim+CL%22">Lim CL</searchLink>; Division of Applied Biomedical Science and Biotechnology, School of Health Sciences, IMU University, Kuala Lumpur, Malaysia.<br /><searchLink fieldCode="AU" term="%22Koh+RY%22">Koh RY</searchLink>; Division of Applied Biomedical Science and Biotechnology, School of Health Sciences, IMU University, Kuala Lumpur, Malaysia.<br /><searchLink fieldCode="AU" term="%22Chandramathi+S%22">Chandramathi S</searchLink>; Department of Medical Microbiology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.<br /><searchLink fieldCode="AU" term="%22Nawaz+M%22">Nawaz M</searchLink>; Department of Nano-Medicine Research, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Pereira+ML%22">Pereira ML</searchLink>; CICECO-Aveiro Institute of Materials and Department of Medical Sciences, University of Aveiro, Aveiro, Portugal.<br /><searchLink fieldCode="AU" term="%22Wiart+C%22">Wiart C</searchLink>; Institute of Tropical Biology and Conservation, University Malaysia Sabah, Kota Kinabalu, Malaysia.<br /><searchLink fieldCode="AU" term="%22Oliveira+SMR%22">Oliveira SMR</searchLink>; CICECO-Aveiro Institute of Materials, University of Aveiro, Aveiro, Portugal.<br /><searchLink fieldCode="AU" term="%22Nissapatorn+V%22">Nissapatorn V</searchLink>; Futuristic Science Reach Center, School of Science, and World Union for Herbal Drug Discovery (WUHeDD), Walailak University, Nakhon Si Thammarat, Thailand.
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              Text: 2025 Dec 19
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