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Small Extracellular Vesicles Secreted by Cisplatin-Resistant Neuroblastoma Cells Increase Lactate Secretion and Alter Metabolic Pathways in Primary Human Umbilical Vein Endothelial Cells (HUVECs).

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Title: Small Extracellular Vesicles Secreted by Cisplatin-Resistant Neuroblastoma Cells Increase Lactate Secretion and Alter Metabolic Pathways in Primary Human Umbilical Vein Endothelial Cells (HUVECs).
Authors: Frawley T; Cancer Bioengineering Group, Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland., Ma L; Cancer Bioengineering Group, Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Kunshan Hospital of Traditional Chinese Medicine, Kunshan 215300, China.; College of Pharmaceutical Sciences, Soochow University, Suzhou 215123, China., Arifin MZ; Systems Biology Ireland, School of Medicine, University College Dublin, Temple Street, D04 C1P1 Dublin, Ireland., Wu D; Department of Chemistry, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland., Scott A; Cancer Bioengineering Group, Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland., Cavanagh B; Cellular and Molecular Imaging Core, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland., O'Shea DF; Department of Chemistry, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Advanced Materials and Bioengineering Research Centre (AMBER), RCSI (D02 YN77) and TCD (D02 CP49), Dublin, Ireland., Zhernovkov V; Systems Biology Ireland, School of Medicine, University College Dublin, Temple Street, D04 C1P1 Dublin, Ireland., Liu M; Kunshan Hospital of Traditional Chinese Medicine, Kunshan 215300, China.; College of Pharmaceutical Sciences, Soochow University, Suzhou 215123, China., Monopoli MP; Department of Chemistry, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Advanced Materials and Bioengineering Research Centre (AMBER), RCSI (D02 YN77) and TCD (D02 CP49), Dublin, Ireland., Piskareva O; Cancer Bioengineering Group, Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Advanced Materials and Bioengineering Research Centre (AMBER), RCSI (D02 YN77) and TCD (D02 CP49), Dublin, Ireland.
Source: Journal of personalized medicine [J Pers Med] 2025 Dec 01; Vol. 15 (12). Date of Electronic Publication: 2025 Dec 01.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101602269 Publication Model: Electronic Cited Medium: Print ISSN: 2075-4426 (Print) Linking ISSN: 20754426 NLM ISO Abbreviation: J Pers Med Subsets: PubMed not MEDLINE
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  Data: Small Extracellular Vesicles Secreted by Cisplatin-Resistant Neuroblastoma Cells Increase Lactate Secretion and Alter Metabolic Pathways in Primary Human Umbilical Vein Endothelial Cells (HUVECs).
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  Data: <searchLink fieldCode="AU" term="%22Frawley+T%22">Frawley T</searchLink>; Cancer Bioengineering Group, Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Ma+L%22">Ma L</searchLink>; Cancer Bioengineering Group, Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Kunshan Hospital of Traditional Chinese Medicine, Kunshan 215300, China.; College of Pharmaceutical Sciences, Soochow University, Suzhou 215123, China.<br /><searchLink fieldCode="AU" term="%22Arifin+MZ%22">Arifin MZ</searchLink>; Systems Biology Ireland, School of Medicine, University College Dublin, Temple Street, D04 C1P1 Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Wu+D%22">Wu D</searchLink>; Department of Chemistry, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Scott+A%22">Scott A</searchLink>; Cancer Bioengineering Group, Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Cavanagh+B%22">Cavanagh B</searchLink>; Cellular and Molecular Imaging Core, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22O'Shea+DF%22">O'Shea DF</searchLink>; Department of Chemistry, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Advanced Materials and Bioengineering Research Centre (AMBER), RCSI (D02 YN77) and TCD (D02 CP49), Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Zhernovkov+V%22">Zhernovkov V</searchLink>; Systems Biology Ireland, School of Medicine, University College Dublin, Temple Street, D04 C1P1 Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Liu+M%22">Liu M</searchLink>; Kunshan Hospital of Traditional Chinese Medicine, Kunshan 215300, China.; College of Pharmaceutical Sciences, Soochow University, Suzhou 215123, China.<br /><searchLink fieldCode="AU" term="%22Monopoli+MP%22">Monopoli MP</searchLink>; Department of Chemistry, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Advanced Materials and Bioengineering Research Centre (AMBER), RCSI (D02 YN77) and TCD (D02 CP49), Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Piskareva+O%22">Piskareva O</searchLink>; Cancer Bioengineering Group, Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, 123 St. Stephen's Green, D02 YN77 Dublin, Ireland.; Advanced Materials and Bioengineering Research Centre (AMBER), RCSI (D02 YN77) and TCD (D02 CP49), Dublin, Ireland.
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  Data: <searchLink fieldCode="JN" term="%22101602269%22">Journal of personalized medicine</searchLink> [J Pers Med] 2025 Dec 01; Vol. 15 (12). <i>Date of Electronic Publication: </i>2025 Dec 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI+AG%22">MDPI AG </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101602269 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2075-4426 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220754426%22">20754426 </searchLink><i>NLM ISO Abbreviation: </i>J Pers Med <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.3390/jpm15120584
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        Text: English
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      – TitleFull: Small Extracellular Vesicles Secreted by Cisplatin-Resistant Neuroblastoma Cells Increase Lactate Secretion and Alter Metabolic Pathways in Primary Human Umbilical Vein Endothelial Cells (HUVECs).
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              Text: 2025 Dec 01
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