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Integrated Multi-Omic Analysis Identifies Altered Colonic Brush Border Profile as a Key Feature of Microscopic Colitis.

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Title: Integrated Multi-Omic Analysis Identifies Altered Colonic Brush Border Profile as a Key Feature of Microscopic Colitis.
Authors: Guagnozzi D; Laboratory of Neuro-immuno-gastroenterology, Vall d'Hebron Institut de Recerca, Barcelona, Spain.; Laboratory of Translational Mucosal Immunology, Vall d'Hebron Institut de Recerca, Barcelona, Spain.; Gastroenterology Department, University Hospital Vall d'Hebron, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain., Gonzalez-Castro AM; Laboratory of Neuro-immuno-gastroenterology, Vall d'Hebron Institut de Recerca, Barcelona, Spain.; Laboratory of Translational Mucosal Immunology, Vall d'Hebron Institut de Recerca, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain., Zabana Y; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain.; Gastroenterology Department, University Hospital Mutua de Terrassa, Barcelona, Spain., Fernández-Bañares F; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain.; Gastroenterology Department, University Hospital Mutua de Terrassa, Barcelona, Spain., Münch A; Gastroenterology Department, Linköping University, Linköping, Sweden., Tristan E; Gastroenterology Department, University Hospital Mutua de Terrassa, Barcelona, Spain., Lozano JJ; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain., Sidorova J; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain., Lobo B; Laboratory of Neuro-immuno-gastroenterology, Vall d'Hebron Institut de Recerca, Barcelona, Spain.; Gastroenterology Department, University Hospital Vall d'Hebron, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain., Alonso-Cotoner C; Laboratory of Neuro-immuno-gastroenterology, Vall d'Hebron Institut de Recerca, Barcelona, Spain.; Gastroenterology Department, University Hospital Vall d'Hebron, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain., Exposito E; Laboratory of Neuro-immuno-gastroenterology, Vall d'Hebron Institut de Recerca, Barcelona, Spain.; Laboratory of Translational Mucosal Immunology, Vall d'Hebron Institut de Recerca, Barcelona, Spain., Lucendo AJ; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain.; Gastroenterology Department, Hospital General de Tomelloso, Ciudad Real, Spain.; Instituto de Investigación Sanitaria de Castilla-La Mancha (IDISCAM), Toledo, Spain., Landolfi S; Pathology Department, University Hospital Vall d'Hebron, Barcelona, Spain., Benages A; Endoscopy Department, University Hospital Vall d'Hebron, Barcelona, Spain., Llerena-Castro R; Gastroenterology Department, University Hospital Vall d'Hebron, Barcelona, Spain., Castillo Cejas MD; Endoscopy Department, University Hospital Vall d'Hebron, Barcelona, Spain., Dot J; Endoscopy Department, University Hospital Vall d'Hebron, Barcelona, Spain., Santos J; Laboratory of Neuro-immuno-gastroenterology, Vall d'Hebron Institut de Recerca, Barcelona, Spain.; Gastroenterology Department, University Hospital Vall d'Hebron, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain., Vicario M; Laboratory of Translational Mucosal Immunology, Vall d'Hebron Institut de Recerca, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain.; Nestlé Institute of Health Sciences, Société Des Produits Nestlé S.A., Nestlé Research, Lausanne, Switzerland.
Source: United European gastroenterology journal [United European Gastroenterol J] 2026 Feb; Vol. 14 (1), pp. e70156.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 101606807 Publication Model: Print Cited Medium: Internet ISSN: 2050-6414 (Electronic) Linking ISSN: 20506406 NLM ISO Abbreviation: United European Gastroenterol J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Integrated Multi-Omic Analysis Identifies Altered Colonic Brush Border Profile as a Key Feature of Microscopic Colitis.
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  Data: <searchLink fieldCode="AU" term="%22Guagnozzi+D%22">Guagnozzi D</searchLink>; Laboratory of Neuro-immuno-gastroenterology, Vall d'Hebron Institut de Recerca, Barcelona, Spain.; Laboratory of Translational Mucosal Immunology, Vall d'Hebron Institut de Recerca, Barcelona, Spain.; Gastroenterology Department, University Hospital Vall d'Hebron, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Gonzalez-Castro+AM%22">Gonzalez-Castro AM</searchLink>; Laboratory of Neuro-immuno-gastroenterology, Vall d'Hebron Institut de Recerca, Barcelona, Spain.; Laboratory of Translational Mucosal Immunology, Vall d'Hebron Institut de Recerca, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Zabana+Y%22">Zabana Y</searchLink>; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain.; Gastroenterology Department, University Hospital Mutua de Terrassa, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Fernández-Bañares+F%22">Fernández-Bañares F</searchLink>; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain.; Gastroenterology Department, University Hospital Mutua de Terrassa, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Münch+A%22">Münch A</searchLink>; Gastroenterology Department, Linköping University, Linköping, Sweden.<br /><searchLink fieldCode="AU" term="%22Tristan+E%22">Tristan E</searchLink>; Gastroenterology Department, University Hospital Mutua de Terrassa, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Lozano+JJ%22">Lozano JJ</searchLink>; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Sidorova+J%22">Sidorova J</searchLink>; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Lobo+B%22">Lobo B</searchLink>; Laboratory of Neuro-immuno-gastroenterology, Vall d'Hebron Institut de Recerca, Barcelona, Spain.; Gastroenterology Department, University Hospital Vall d'Hebron, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Alonso-Cotoner+C%22">Alonso-Cotoner C</searchLink>; Laboratory of Neuro-immuno-gastroenterology, Vall d'Hebron Institut de Recerca, Barcelona, Spain.; Gastroenterology Department, University Hospital Vall d'Hebron, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Exposito+E%22">Exposito E</searchLink>; Laboratory of Neuro-immuno-gastroenterology, Vall d'Hebron Institut de Recerca, Barcelona, Spain.; Laboratory of Translational Mucosal Immunology, Vall d'Hebron Institut de Recerca, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Lucendo+AJ%22">Lucendo AJ</searchLink>; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain.; Gastroenterology Department, Hospital General de Tomelloso, Ciudad Real, Spain.; Instituto de Investigación Sanitaria de Castilla-La Mancha (IDISCAM), Toledo, Spain.<br /><searchLink fieldCode="AU" term="%22Landolfi+S%22">Landolfi S</searchLink>; Pathology Department, University Hospital Vall d'Hebron, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Benages+A%22">Benages A</searchLink>; Endoscopy Department, University Hospital Vall d'Hebron, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Llerena-Castro+R%22">Llerena-Castro R</searchLink>; Gastroenterology Department, University Hospital Vall d'Hebron, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Castillo+Cejas+MD%22">Castillo Cejas MD</searchLink>; Endoscopy Department, University Hospital Vall d'Hebron, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Dot+J%22">Dot J</searchLink>; Endoscopy Department, University Hospital Vall d'Hebron, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Santos+J%22">Santos J</searchLink>; Laboratory of Neuro-immuno-gastroenterology, Vall d'Hebron Institut de Recerca, Barcelona, Spain.; Gastroenterology Department, University Hospital Vall d'Hebron, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Vicario+M%22">Vicario M</searchLink>; Laboratory of Translational Mucosal Immunology, Vall d'Hebron Institut de Recerca, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBER-EHD), Madrid, Spain.; Nestlé Institute of Health Sciences, Société Des Produits Nestlé S.A., Nestlé Research, Lausanne, Switzerland.
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