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The biochemical dynamics of the glycogen phosphatase laforin directly impact brain metabolism.

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Title: The biochemical dynamics of the glycogen phosphatase laforin directly impact brain metabolism.
Authors: Brewer MK; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, Kentucky, USA., Donohue KJ; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, Kentucky, USA., Singh PK; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA., Raththagala M; Department of Chemistry, Skidmore College, Saratoga Springs, New York, USA., Simmons ZR; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, Kentucky, USA., Wayne JL; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, Kentucky, USA., Li S; Department of Medicine, University of California at San Diego, La Jolla, California, USA., Viana R; Instituto de Biomedicina de Valencia, CSIC and Centro de Investigación Biomedica en Red de Enfermedades Raras (CIBERER), Valencia, Spain., Segvich DM; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA., Contreras CJ; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA., Cantrell AR; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA., Sanz P; Instituto de Biomedicina de Valencia, CSIC and Centro de Investigación Biomedica en Red de Enfermedades Raras (CIBERER), Valencia, Spain., Sun RC; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA., Vander Kooi CW; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA., Roach PJ; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA., DePaoli-Roach A; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA., Gentry MS; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA. Electronic address: matthew.gentry@ufl.edu.
Source: The Journal of biological chemistry [J Biol Chem] 2026 Feb; Vol. 302 (2), pp. 111097. Date of Electronic Publication: 2025 Dec 22.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Brewer+MK%22">Brewer MK</searchLink>; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, Kentucky, USA.<br /><searchLink fieldCode="AU" term="%22Donohue+KJ%22">Donohue KJ</searchLink>; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, Kentucky, USA.<br /><searchLink fieldCode="AU" term="%22Singh+PK%22">Singh PK</searchLink>; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Raththagala+M%22">Raththagala M</searchLink>; Department of Chemistry, Skidmore College, Saratoga Springs, New York, USA.<br /><searchLink fieldCode="AU" term="%22Simmons+ZR%22">Simmons ZR</searchLink>; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, Kentucky, USA.<br /><searchLink fieldCode="AU" term="%22Wayne+JL%22">Wayne JL</searchLink>; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, Kentucky, USA.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Department of Medicine, University of California at San Diego, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Viana+R%22">Viana R</searchLink>; Instituto de Biomedicina de Valencia, CSIC and Centro de Investigación Biomedica en Red de Enfermedades Raras (CIBERER), Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Segvich+DM%22">Segvich DM</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Contreras+CJ%22">Contreras CJ</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Cantrell+AR%22">Cantrell AR</searchLink>; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Sanz+P%22">Sanz P</searchLink>; Instituto de Biomedicina de Valencia, CSIC and Centro de Investigación Biomedica en Red de Enfermedades Raras (CIBERER), Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Sun+RC%22">Sun RC</searchLink>; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Vander+Kooi+CW%22">Vander Kooi CW</searchLink>; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Roach+PJ%22">Roach PJ</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22DePaoli-Roach+A%22">DePaoli-Roach A</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Gentry+MS%22">Gentry MS</searchLink>; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA. Electronic address: matthew.gentry@ufl.edu.
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  Data: <searchLink fieldCode="JN" term="%222985121R%22">The Journal of biological chemistry</searchLink> [J Biol Chem] 2026 Feb; Vol. 302 (2), pp. 111097. <i>Date of Electronic Publication: </i>2025 Dec 22.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Inc%2E+on+behalf+of+American+Society+for+Biochemistry+and+Molecular+Biology%22">Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2985121R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1083-351X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219258%22">00219258 </searchLink><i>NLM ISO Abbreviation: </i>J Biol Chem <i>Subsets: </i>MEDLINE
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