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Pachyphylinin A-B: two novel seco-apotirucallane triterpenoids with cytotoxic activities from the stem bark of Aglaia pachyphylla.

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Title: Pachyphylinin A-B: two novel seco-apotirucallane triterpenoids with cytotoxic activities from the stem bark of Aglaia pachyphylla.
Authors: Safriansyah W; Eijkman Research Center for Molecular Biology, National Research and Innovation Agency, Jalan Raya Bogor Km. 46, Cibinong, Bogor, 16911, Indonesia., Hilmayanti E; Department of Chemistry, Graduate School of Science, Osaka University, Toyonaka, 560-0043, Japan.; Institute for Radiation Sciences, Osaka University, Toyonaka, 560-0043, Japan., Rustaman; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor, 45363, Indonesia., Farabi K; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor, 45363, Indonesia., Nafiah MA; Department of Chemistry, Faculty of Science and Mathematics, Sultan Idris Education University, Tanjung Malim, 35900, Perak, Malaysia., Azmi MN; School of Chemical Sciences, Universiti Sains Malaysia, Minden, Penang, 11800, Malaysia., Fajriah S; Research Center for Chemistry, National Research and Innovation Agency (BRIN), Kawasan PUSPITEK, Serpong, Tangerang Selatan, 15314, Indonesia., Kabayama K; Department of Chemistry, Graduate School of Science, Osaka University, Toyonaka, 560-0043, Japan.; Forefront Research Center, Graduate School of Science, Osaka University, Toyonaka, 560-0043, Japan., Shimoyama A; Department of Chemistry, Graduate School of Science, Osaka University, Toyonaka, 560-0043, Japan.; Forefront Research Center, Graduate School of Science, Osaka University, Toyonaka, 560-0043, Japan., Manabe Y; Department of Chemistry, Graduate School of Science, Osaka University, Toyonaka, 560-0043, Japan.; Forefront Research Center, Graduate School of Science, Osaka University, Toyonaka, 560-0043, Japan., Fukase K; Department of Chemistry, Graduate School of Science, Osaka University, Toyonaka, 560-0043, Japan.; Forefront Research Center, Graduate School of Science, Osaka University, Toyonaka, 560-0043, Japan., Kuncoro H; Faculty of Pharmacy, Mulawarman University, Samarinda, 75119, Indonesia., Supratman U; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor, 45363, Indonesia.; Central Laboratory, Universitas Padjadjaran, Jatinangor, 45363, Indonesia., Harneti D; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor, 45363, Indonesia. desi.harneti@unpad.ac.id.
Source: Journal of natural medicines [J Nat Med] 2026 Jan; Vol. 80 (1), pp. 199-206. Date of Electronic Publication: 2025 Dec 24.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Japan NLM ID: 101518405 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1861-0293 (Electronic) Linking ISSN: 13403443 NLM ISO Abbreviation: J Nat Med Subsets: MEDLINE
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  Data: Pachyphylinin A-B: two novel seco-apotirucallane triterpenoids with cytotoxic activities from the stem bark of Aglaia pachyphylla.
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  Data: <searchLink fieldCode="AU" term="%22Safriansyah+W%22">Safriansyah W</searchLink>; Eijkman Research Center for Molecular Biology, National Research and Innovation Agency, Jalan Raya Bogor Km. 46, Cibinong, Bogor, 16911, Indonesia.<br /><searchLink fieldCode="AU" term="%22Hilmayanti+E%22">Hilmayanti E</searchLink>; Department of Chemistry, Graduate School of Science, Osaka University, Toyonaka, 560-0043, Japan.; Institute for Radiation Sciences, Osaka University, Toyonaka, 560-0043, Japan.<br /><searchLink fieldCode="AU" term="%22Rustaman%22">Rustaman</searchLink>; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor, 45363, Indonesia.<br /><searchLink fieldCode="AU" term="%22Farabi+K%22">Farabi K</searchLink>; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor, 45363, Indonesia.<br /><searchLink fieldCode="AU" term="%22Nafiah+MA%22">Nafiah MA</searchLink>; Department of Chemistry, Faculty of Science and Mathematics, Sultan Idris Education University, Tanjung Malim, 35900, Perak, Malaysia.<br /><searchLink fieldCode="AU" term="%22Azmi+MN%22">Azmi MN</searchLink>; School of Chemical Sciences, Universiti Sains Malaysia, Minden, Penang, 11800, Malaysia.<br /><searchLink fieldCode="AU" term="%22Fajriah+S%22">Fajriah S</searchLink>; Research Center for Chemistry, National Research and Innovation Agency (BRIN), Kawasan PUSPITEK, Serpong, Tangerang Selatan, 15314, Indonesia.<br /><searchLink fieldCode="AU" term="%22Kabayama+K%22">Kabayama K</searchLink>; Department of Chemistry, Graduate School of Science, Osaka University, Toyonaka, 560-0043, Japan.; Forefront Research Center, Graduate School of Science, Osaka University, Toyonaka, 560-0043, Japan.<br /><searchLink fieldCode="AU" term="%22Shimoyama+A%22">Shimoyama A</searchLink>; Department of Chemistry, Graduate School of Science, Osaka University, Toyonaka, 560-0043, Japan.; Forefront Research Center, Graduate School of Science, Osaka University, Toyonaka, 560-0043, Japan.<br /><searchLink fieldCode="AU" term="%22Manabe+Y%22">Manabe Y</searchLink>; Department of Chemistry, Graduate School of Science, Osaka University, Toyonaka, 560-0043, Japan.; Forefront Research Center, Graduate School of Science, Osaka University, Toyonaka, 560-0043, Japan.<br /><searchLink fieldCode="AU" term="%22Fukase+K%22">Fukase K</searchLink>; Department of Chemistry, Graduate School of Science, Osaka University, Toyonaka, 560-0043, Japan.; Forefront Research Center, Graduate School of Science, Osaka University, Toyonaka, 560-0043, Japan.<br /><searchLink fieldCode="AU" term="%22Kuncoro+H%22">Kuncoro H</searchLink>; Faculty of Pharmacy, Mulawarman University, Samarinda, 75119, Indonesia.<br /><searchLink fieldCode="AU" term="%22Supratman+U%22">Supratman U</searchLink>; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor, 45363, Indonesia.; Central Laboratory, Universitas Padjadjaran, Jatinangor, 45363, Indonesia.<br /><searchLink fieldCode="AU" term="%22Harneti+D%22">Harneti D</searchLink>; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor, 45363, Indonesia. desi.harneti@unpad.ac.id.
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