Prolonged Loss of Oxidative Phosphorylation and Mitochondrial Mass Characterize CD66b+ Leukocytes from Patients with Sepsis.

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Title: Prolonged Loss of Oxidative Phosphorylation and Mitochondrial Mass Characterize CD66b+ Leukocytes from Patients with Sepsis.
Authors: Rodhouse C; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Barrios EL; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Zeumer-Spataro L; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Balzano-Nogueira L; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA., Wu R; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.; Department of Biostatistics, University of Florida Colleges of Medicine and Public Health and Health Sciences, Gainesville, FL, USA., Yu X; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.; Department of Biostatistics, University of Florida Colleges of Medicine and Public Health and Health Sciences, Gainesville, FL, USA., Tian G; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Brant JO; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA., Gauthier ML; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA., Chen J; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine; Gainesville, Florida, USA., Hernandez-Rios M; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Polcz VE; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Wiggins W; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Charles AM; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Dirain ML; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Ungaro R; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Rincon J; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Loftus T; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Xiao F; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.; Department of Biostatistics, University of Florida Colleges of Medicine and Public Health and Health Sciences, Gainesville, FL, USA., Cai G; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Moldawer LL; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Maile R; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Kladde MP; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, Florida, USA., Efron PA; Sepsis and Critical Illness Research Center, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA., Mathews CE; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine; Gainesville, Florida, USA.; Department of Infectious Diseases and Immunology, University of Florida College of Veterinary Medicine; Gainesville, Florida, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Dec 18. Date of Electronic Publication: 2025 Dec 18.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.64898/2025.12.16.694726